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  1. 050 医学部, 大学院医学系研究科
  2. 0502 紀要・刊行物
  3. 05021 信州医学雑誌
  4. Vol. 49 No. 2

リンパ節転移陰性乳癌組織におけるthymidine phosphorylase発現症例の検討

http://hdl.handle.net/10091/9294
41815a26-9a50-4f16-9ddf-3b9c477a9eff
名前 / ファイル ライセンス アクション
Shinshu_Med49-2-03.pdf Shinshu_Med49-2-03.pdf (314.1 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2010-03-24
タイトル
タイトル リンパ節転移陰性乳癌組織におけるthymidine phosphorylase発現症例の検討
言語
言語 jpn
キーワード
主題Scheme Other
主題 thymidine phosphorylase
キーワード
主題Scheme Other
主題 node-negative
キーワード
主題Scheme Other
主題 breast cancer
キーワード
主題Scheme Other
主題 medroxyprogesterone
キーワード
主題Scheme Other
主題 doxifluridine
キーワード
主題Scheme Other
主題 チミジンホスホリラーゼ
キーワード
主題Scheme Other
主題 リンパ節陰性
キーワード
主題Scheme Other
主題 乳癌
キーワード
主題Scheme Other
主題 メドロキシプロゲステロン
キーワード
主題Scheme Other
主題 ドキシフルリジン
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
その他(別言語等)のタイトル
その他のタイトル Clinicopathological Significance of Thymidine Phosphorylase Expressed in Node-Negative Breast Cancer Tumors
著者 本原, 昭子

× 本原, 昭子

WEKO 10159

本原, 昭子

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麻沼, 和彦

× 麻沼, 和彦

WEKO 10160

麻沼, 和彦

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藤森, 実

× 藤森, 実

WEKO 10161

藤森, 実

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土屋, 眞一

× 土屋, 眞一

WEKO 10162

土屋, 眞一

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浜, 善久

× 浜, 善久

WEKO 10163

浜, 善久

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丸山, 正幸

× 丸山, 正幸

WEKO 10164

丸山, 正幸

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草間, 律

× 草間, 律

WEKO 10165

草間, 律

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天野, 純

× 天野, 純

WEKO 10166

天野, 純

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出版者
出版者 信州医学会
引用
内容記述タイプ Other
内容記述 信州医学雑誌 49(2): 79-83(2001)
書誌情報 信州医学雑誌

巻 49, 号 2, p. 79-83, 発行日 2001-04
抄録
内容記述タイプ Abstract
内容記述 The expression of thymidine phosphorylase (dThd Pase) in node-negative human invasive ductal carcinoma tissues was investigated by the immunocytochemical method using anti-thymidine phosphorylase monoclonal antibody.Subjects were 5 recurrent and 30 non-recurrent patients who underwent surgery at the Department of Surgery at Shinshu University Hospital between 1993 and 1996.The median follow-up period was 62.5 months.Positive dThd Pase staining was observed in the five recurrent and four non-recurrent cases. Tumor recurrence was significantly more developed in patients with dThd Pase positive staining than in those with negative staining (p<0.01).Among the nine dThd Pase positive cases,four patients who were administered doxifluridine (5’-DFUR) or medroxyprogesterone (MPA) did not manifest recurrence. Among the recurrent patients, two were cured by oral administration of 5’-DFUR or MPA. It is suggested that the expression of thymidine phosphorylase in human breast cancer tissues may be a risk factor for tumor recurrence. The prognosis of node-negative and dThd Pase positive breast cancer patients might be improved by hormonal therapy or oral administration of 5’-DFUR.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ ISSN
収録物識別子 0037-3826
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00120815
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