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リンパ節転移陰性乳癌組織におけるthymidine phosphorylase発現症例の検討
http://hdl.handle.net/10091/9294
41815a26-9a50-4f16-9ddf-3b9c477a9eff
名前 / ファイル | ライセンス | アクション | |
---|---|---|---|
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2010-03-24 | |||||
タイトル | ||||||
タイトル | リンパ節転移陰性乳癌組織におけるthymidine phosphorylase発現症例の検討 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | thymidine phosphorylase | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | node-negative | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | breast cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | medroxyprogesterone | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | doxifluridine | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | チミジンホスホリラーゼ | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | リンパ節陰性 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 乳癌 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | メドロキシプロゲステロン | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ドキシフルリジン | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
その他(別言語等)のタイトル | ||||||
その他のタイトル | Clinicopathological Significance of Thymidine Phosphorylase Expressed in Node-Negative Breast Cancer Tumors | |||||
著者 |
本原, 昭子
× 本原, 昭子× 麻沼, 和彦× 藤森, 実× 土屋, 眞一× 浜, 善久× 丸山, 正幸× 草間, 律× 天野, 純 |
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出版者 | ||||||
出版者 | 信州医学会 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 信州医学雑誌 49(2): 79-83(2001) | |||||
書誌情報 |
信州医学雑誌 巻 49, 号 2, p. 79-83, 発行日 2001-04 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The expression of thymidine phosphorylase (dThd Pase) in node-negative human invasive ductal carcinoma tissues was investigated by the immunocytochemical method using anti-thymidine phosphorylase monoclonal antibody.Subjects were 5 recurrent and 30 non-recurrent patients who underwent surgery at the Department of Surgery at Shinshu University Hospital between 1993 and 1996.The median follow-up period was 62.5 months.Positive dThd Pase staining was observed in the five recurrent and four non-recurrent cases. Tumor recurrence was significantly more developed in patients with dThd Pase positive staining than in those with negative staining (p<0.01).Among the nine dThd Pase positive cases,four patients who were administered doxifluridine (5’-DFUR) or medroxyprogesterone (MPA) did not manifest recurrence. Among the recurrent patients, two were cured by oral administration of 5’-DFUR or MPA. It is suggested that the expression of thymidine phosphorylase in human breast cancer tissues may be a risk factor for tumor recurrence. The prognosis of node-negative and dThd Pase positive breast cancer patients might be improved by hormonal therapy or oral administration of 5’-DFUR. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0037-3826 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00120815 |