@article{oai:soar-ir.repo.nii.ac.jp:00004367, author = {花岡, 孝臣 and 青木, 孝學 and 牧内, 明子 and 沼波, 宏樹 and 近藤, 竜一 and 高砂, 敬一郎 and 町田, 恵美 and 宮澤, 正久 and 金子, 和彦 and 矢満田, 健 and 羽生田, 正行 and 藤森, 実 and 福嶋, 義光 and 天野, 純}, issue = {6}, journal = {信州医学雑誌}, month = {Dec}, note = {Recent studies indicate that soluble tumor DNA and microsatellite alterations have been identified in the peripheral blood of small cell lung cancer patients. There is a possibility that these might be useful for preoperative diagnosis, deciding on treatment strategy and postoperative evaluation as a new biomarker to detect genetic alterations originating from primary cancerous lesions in the peripheral blood of non-small cell lung cancer patients. The purpose of this study was to determine whether genetic alterations in resected cancer tissue could be identified in the preoperative peripheral serum by microsatellite DNA analysis. Our preliminary data, however, showed that no microsatellite alterations in tumor DNA could be found in the preoperative serum DNA of non-small cell lung cancer patients., Article, 信州医学雑誌 47(6): 489-495(1999)}, pages = {489--495}, title = {非小細胞肺癌における血清DNAを用いたマイクロサテライト変異の検討}, volume = {47}, year = {1999} }