{"created":"2021-03-01T06:08:11.960136+00:00","id":4367,"links":{},"metadata":{"_buckets":{"deposit":"ee5fd8c9-2e15-4a49-80e2-8ff275fa44b7"},"_deposit":{"id":"4367","owners":[],"pid":{"revision_id":0,"type":"depid","value":"4367"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:00004367","sets":["461:463:464:557"]},"author_link":["10307","10308","10309","10310","10311","10312","10313","10314","10315","10316","10317","10318","10319","10320"],"item_1628147817048":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1999-12-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"495","bibliographicPageStart":"489","bibliographicVolumeNumber":"47","bibliographic_titles":[{"bibliographic_title":"信州医学雑誌"}]}]},"item_6_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Recent studies indicate that soluble tumor DNA and microsatellite alterations have been identified in the peripheral blood of small cell lung cancer patients. There is a possibility that these might be useful for preoperative diagnosis, deciding on treatment strategy and postoperative evaluation as a new biomarker to detect genetic alterations originating from primary cancerous lesions in the peripheral blood of non-small cell lung cancer patients. The purpose of this study was to determine whether genetic alterations in resected cancer tissue could be identified in the preoperative peripheral serum by microsatellite DNA analysis. Our preliminary data, however, showed that no microsatellite alterations in tumor DNA could be found in the preoperative serum DNA of non-small cell lung cancer patients.","subitem_description_type":"Abstract"}]},"item_6_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_6_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"信州医学雑誌 47(6): 489-495(1999)","subitem_description_type":"Other"}]},"item_6_link_3":{"attribute_name":"信州大学研究者総覧へのリンク","attribute_value_mlt":[{"subitem_link_text":"福嶋, 義光","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.OUnVuUkh.html"}]},"item_6_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"信州医学会"}]},"item_6_source_id_35":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0037-3826","subitem_source_identifier_type":"PISSN"}]},"item_6_source_id_40":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00120815","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"花岡,  孝臣","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"青木,  孝學","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"牧内,  明子","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"沼波,  宏樹","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"近藤,  竜一","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"高砂,  敬一郎","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"町田,  恵美","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"宮澤,  正久","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"金子,  和彦","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"矢満田,  健","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"羽生田,  正行","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"藤森,  実","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"福嶋,  義光","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"天野,  純","creatorNameLang":"ja"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-09-24"}],"displaytype":"detail","filename":"Shinshu_Med47-6-03.pdf","filesize":[{"value":"455.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Shinshu_Med47-6-03.pdf","url":"https://soar-ir.repo.nii.ac.jp/record/4367/files/Shinshu_Med47-6-03.pdf"},"version_id":"87731e2e-81a0-4e3d-9dfa-45f81fbfeb8a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"non-small cell lung cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"serum DNA","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"microsatellite DNA analysis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"PCR","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"LOH","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"非小細胞肺癌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"血清DNA","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"マイクロサテライトDNA 分析","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ポリメラーゼ連鎖反応","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ヘテロ接合性の消失","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal 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