{"created":"2021-03-01T06:10:46.732499+00:00","id":6933,"links":{},"metadata":{"_buckets":{"deposit":"2dc64771-8a86-4ce6-b5cc-c95953464de6"},"_deposit":{"id":"6933","owners":[],"pid":{"revision_id":0,"type":"depid","value":"6933"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:00006933","sets":["461:463:805:814"]},"author_link":["16822","16823","16824"],"item_10_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1994-02-28","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"28","bibliographicPageStart":"23","bibliographicVolumeNumber":"19","bibliographic_titles":[{"bibliographic_title":"紀要"}]}]},"item_10_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The sugar chain residue of thyroglobulin produced in thyroid cancer (C-Tg) has a modified structure compared with that in the normal thyroid (N-Tg). We have measured the remaining unbound-thyroglobulin (ub-Tg) in thyroid specimens by an enzyme immunoassay (EIA) after treatment with concanavalin A (ConA) lectin, taking advantage of different affinity of C-Tg to lectin. Three thyroid tissue specimens ( 1 normal, 1 papillary  carcinoma, 1 benign goitor) and 28 thyroid aspirated specimens (16 papillary carcinoma and 12 benign goiter) were analyzed. Tg to lectin ratio of 1 : 3 was at the zenith of the ub-Tg％. Thus, ConA at a ratio of 1 : 3 were used for subsequent studies. The ub-Tg value for papillary carcinoma tissue was significantly higher than the benign goiter. Five of 16 specimens obtained by aspiration from thyroid cancer manifested elevated ub-Tg levels after ConA treatment. Thus, measurement of ub-Tg in thyroid aspirated specimens after treatment with ConA may prove to be useful for the diagnosis of thyroid cancer.","subitem_description_type":"Abstract"}]},"item_10_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_10_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"紀要 19: 23-28(1994)","subitem_description_type":"Other"}]},"item_10_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"信州大学医療技術短期大学部"}]},"item_10_source_id_35":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-1982","subitem_source_identifier_type":"ISSN"}]},"item_10_source_id_40":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10402438","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"加藤,  亮二","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"菅谷,  昭","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"飯田,  太"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-09-25"}],"displaytype":"detail","filename":"Allied_Med19_04.pdf","filesize":[{"value":"649.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Allied_Med19_04.pdf","url":"https://soar-ir.repo.nii.ac.jp/record/6933/files/Allied_Med19_04.pdf"},"version_id":"8dc2bea4-ec38-4faa-830a-f414ce9279ad"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Lectin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ConcanvalinA","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Thyroglobulin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Aspirated Specimens","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Thyroid Cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"レクチン","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"コンカナバリンA","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"サイログロブリン","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"穿刺液","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"甲状腺癌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"甲状腺穿刺液サイログロブリンのレクチン親和測定法 : 甲状腺分化癌診断の可能性","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"甲状腺穿刺液サイログロブリンのレクチン親和測定法 : 甲状腺分化癌診断の可能性","subitem_title_language":"ja"},{"subitem_title":"A Novel Lectin-Affinity Assay of Thyroglobulin in Thyroid Aspirated Specimens : A Clue to the Diagnosis of Differentiated Thyroid Cancer","subitem_title_language":"en"}]},"item_type_id":"10","owner":"1","path":["814"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2010-03-01"},"publish_date":"2010-03-01","publish_status":"0","recid":"6933","relation_version_is_last":true,"title":["甲状腺穿刺液サイログロブリンのレクチン親和測定法 : 甲状腺分化癌診断の可能性"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-02-13T01:06:48.301107+00:00"}