{"_buckets": {"deposit": "118d4d21-1ee9-4fba-8e7d-afd88849d3c4"}, "_deposit": {"id": "7187", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "7187"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00007187"}, "item_6_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2012-05", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "10", "bibliographicPageEnd": "2231", "bibliographicPageStart": "2225", "bibliographicVolumeNumber": "590", "bibliographic_titles": [{"bibliographic_title": "JOURNAL OF PHYSIOLOGY-LONDON"}]}]}, "item_6_description_19": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u4fe1\u5dde\u5927\u5b66\u535a\u58eb\uff08\u533b\u5b66\uff09\u30fb\u5b66\u4f4d\u8ad6\u6587\u30fb\u5e73\u621024\u5e743\u670831\u65e5\u6388\u4e0e\uff08\u7532\u7b2c940\u53f7\uff09\u30fb\u6749\u5c71 \u5927\u4ecb", "subitem_description_type": "Other"}, {"subitem_description": "\u2018The definitive version is available at www.blackwell-synergy.com\u2019 and www.jphysiol.org .", "subitem_description_type": "Other"}]}, "item_6_description_20": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Locus coeruleus (LC) neurones extend noradrenergic projections throughout the neuroaxis and are involved in homeostatic functions such as pain modulation, arousal and cardio-respiratory control. To address the cellular mechanisms underlying pain modulation we have developed a patch-clamp recording technique from LC neurones in anaesthetized rats. These recordings showed LC discharge in vivo to be driven by both spontaneous membrane potential oscillations and CNQX-sensitive EPSCs opposed by bicuculine-sensitive IPSCs. Hindlimb pinch evoked a biphasic action potential response underpinned by a slow monophasic excitatory current. This approach allows detailed characterisation of the synaptic and integrative mechanisms of LC responses to naturalistic stimulation.", "subitem_description_type": "Abstract"}]}, "item_6_description_30": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7\uff08\u30b3\u30f3\u30c6\u30f3\u30c4\u306e\u7a2e\u985e\uff09", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "\u5f15\u7528", "attribute_value_mlt": [{"subitem_description": "JOURNAL OF PHYSIOLOGY-LONDON. 590(10):2225-2231 (2012)", "subitem_description_type": "Other"}]}, "item_6_publisher_4": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "WILEY-BLACKWELL"}]}, "item_6_relation_48": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1113/jphysiol.2011.226407"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://dx.doi.org/10.1113/jphysiol.2011.226407", "subitem_relation_type_select": "DOI"}}]}, "item_6_select_64": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0022-3751", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Sugiyama,  Daisuke"}], "nameIdentifiers": [{"nameIdentifier": "17392", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hur,  Sung Won"}], "nameIdentifiers": [{"nameIdentifier": "17393", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Pickering,  Anthony E."}], "nameIdentifiers": [{"nameIdentifier": "17394", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kase,  Daisuke"}], "nameIdentifiers": [{"nameIdentifier": "17395", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kim,  Sang Jeong"}], "nameIdentifiers": [{"nameIdentifier": "17396", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawamata,  Mikito"}], "nameIdentifiers": [{"nameIdentifier": "17397", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Imoto,  Keiji"}], "nameIdentifiers": [{"nameIdentifier": "17398", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Furue,  Hidemasa"}], "nameIdentifiers": [{"nameIdentifier": "17399", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-25"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "H24Kou940_Sugiyama.pdf", "filesize": [{"value": "1.7 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1700000.0, "url": {"label": "H24Kou940_Sugiyama.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/7187/files/H24Kou940_Sugiyama.pdf"}, "version_id": "1804129d-5fd1-4973-9d1e-ea4f5e6ae94c"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "In vivo patch-clamp recording from locus coeruleus neurones in the rat brainstem", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "In vivo patch-clamp recording from locus coeruleus neurones in the rat brainstem"}]}, "item_type_id": "6", "owner": "1", "path": ["461/848/849"], "permalink_uri": "http://hdl.handle.net/10091/17657", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2014-06-27"}, "publish_date": "2014-06-27", "publish_status": "0", "recid": "7187", "relation": {}, "relation_version_is_last": true, "title": ["In vivo patch-clamp recording from locus coeruleus neurones in the rat brainstem"], "weko_shared_id": null}