{"created":"2021-03-01T06:11:02.156737+00:00","id":7187,"links":{},"metadata":{"_buckets":{"deposit":"118d4d21-1ee9-4fba-8e7d-afd88849d3c4"},"_deposit":{"id":"7187","owners":[],"pid":{"revision_id":0,"type":"depid","value":"7187"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:00007187","sets":["461:848:849"]},"author_link":["17392","17393","17394","17395","17396","17397","17398","17399"],"item_1628147817048":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"10","bibliographicPageEnd":"2231","bibliographicPageStart":"2225","bibliographicVolumeNumber":"590","bibliographic_titles":[{"bibliographic_title":"JOURNAL OF PHYSIOLOGY-LONDON"}]}]},"item_6_description_19":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"信州大学博士（医学）・学位論文・平成24年3月31日授与（甲第940号）・杉山 大介","subitem_description_type":"Other"},{"subitem_description":"‘The definitive version is available at www.blackwell-synergy.com’ and www.jphysiol.org .","subitem_description_type":"Other"}]},"item_6_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Locus coeruleus (LC) neurones extend noradrenergic projections throughout the neuroaxis and are involved in homeostatic functions such as pain modulation, arousal and cardio-respiratory control. To address the cellular mechanisms underlying pain modulation we have developed a patch-clamp recording technique from LC neurones in anaesthetized rats. These recordings showed LC discharge in vivo to be driven by both spontaneous membrane potential oscillations and CNQX-sensitive EPSCs opposed by bicuculine-sensitive IPSCs. Hindlimb pinch evoked a biphasic action potential response underpinned by a slow monophasic excitatory current. This approach allows detailed characterisation of the synaptic and integrative mechanisms of LC responses to naturalistic stimulation.","subitem_description_type":"Abstract"}]},"item_6_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_6_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"JOURNAL OF PHYSIOLOGY-LONDON. 590(10):2225-2231 (2012)","subitem_description_type":"Other"}]},"item_6_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"WILEY-BLACKWELL"}]},"item_6_relation_48":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1113/jphysiol.2011.226407"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1113/jphysiol.2011.226407","subitem_relation_type_select":"DOI"}}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sugiyama,  Daisuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hur,  Sung Won"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Pickering,  Anthony E."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kase,  Daisuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kim,  Sang Jeong"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawamata,  Mikito"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Imoto,  Keiji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Furue,  Hidemasa"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-09-25"}],"displaytype":"detail","filename":"H24Kou940_Sugiyama.pdf","filesize":[{"value":"1.7 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"H24Kou940_Sugiyama.pdf","url":"https://soar-ir.repo.nii.ac.jp/record/7187/files/H24Kou940_Sugiyama.pdf"},"version_id":"1804129d-5fd1-4973-9d1e-ea4f5e6ae94c"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"In vivo patch-clamp recording from locus coeruleus neurones in the rat brainstem","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"In vivo patch-clamp recording from locus coeruleus neurones in the rat brainstem","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["849"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-06-27"},"publish_date":"2014-06-27","publish_status":"0","recid":"7187","relation_version_is_last":true,"title":["In vivo patch-clamp recording from locus coeruleus neurones in the rat brainstem"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-12-14T03:54:10.470470+00:00"}