{"created":"2021-03-01T06:11:02.872691+00:00","id":7199,"links":{},"metadata":{"_buckets":{"deposit":"ea9e01c0-9d22-4d92-9ef6-6b101b245109"},"_deposit":{"id":"7199","owners":[],"pid":{"revision_id":0,"type":"depid","value":"7199"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:00007199","sets":["461:848:849"]},"author_link":["17491","17492","17493","17494","17495","17496","17497","17498","17499","17500","17501","17502","17503","17504","17505","17506"],"item_1628147817048":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"993","bibliographicPageStart":"981","bibliographicVolumeNumber":"7","bibliographic_titles":[{"bibliographic_title":"NANOMEDICINE"}]}]},"item_6_description_19":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"信州大学博士（医学）・学位論文・平成23年3月31日授与（甲第906号)・荻原伸英","subitem_description_type":"Other"}]},"item_6_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The addition of carbon nanotubes (CNTs) remarkably improves the mechanical characteristics of base materials. CNT/alumina ceramic composites are expected to be highly functional biomaterials useful in a variety of medical fields. Biocompatibility and bone tissue compatibility were studied for the application of CNT/alumina composites as biomaterials. Methods & results: Inflammation reactions in response to the composite were as mild as those of alumina ceramic alone in a subcutaneous implantation study. In bone implantation testing, the composite showed good bone tissue compatibility and connected directly to new bone. An in vitro cell attachment test was performed for osteoblasts, chondrocytes, fibroblasts and smooth muscle cells, and CNT/alumina composite showed cell attachment similar to that of alumina ceramic. Discussion & conclusion: Owing to proven good biocompatibility and bone tissue compatibility, the application of CNT/alumina composites as biomaterials that contact bone, such as prostheses in arthroplasty and devices for bone repair, are expected.","subitem_description_type":"Abstract"}]},"item_6_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_6_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"NANOMEDICINE. 7(7):981-993 (2012)","subitem_description_type":"Other"}]},"item_6_link_3":{"attribute_name":"信州大学研究者総覧へのリンク","attribute_value_mlt":[{"subitem_link_text":"Aoki, Kaoru","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.WeDpbhym.html"},{"subitem_link_text":"Kato, Hiroyuki","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.WVkCbaSp.html"},{"subitem_link_text":"Haniu, Hisao","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.jakpPmSa.html"},{"subitem_link_text":"Nakayama, Noboru","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.WNfpbpkh.html"},{"subitem_link_text":"Taruta, Seiichi","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.OacaZVkh.html"},{"subitem_link_text":"Saito, Naoto","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.WpkhuUkh.html"}]},"item_6_link_67":{"attribute_name":"WoS","attribute_value_mlt":[{"subitem_link_url":"http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000306620700015"}]},"item_6_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"FUTURE MEDICINE LTD"}]},"item_6_relation_47":{"attribute_name":"PubMed","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"22401267"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=22401267","subitem_relation_type_select":"PMID"}}]},"item_6_relation_48":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.2217/NNM.12.1"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2217/NNM.12.1","subitem_relation_type_select":"DOI"}}]},"item_6_source_id_35":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1743-5889","subitem_source_identifier_type":"ISSN"}]},"item_6_source_id_40":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12157344","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ogihara,  Nobuhide"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Usui,  Yuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Aoki,  Kaoru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimizu,  Masayuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Narita,  Nobuyo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hara,  Kazuo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakamura,  Koichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishigaki,  Norio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takanashi,  Seiji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Okamoto,  Masanori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kato,  Hiroyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Haniu,  Hisao"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ogiwara,  Naoko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakayama,  Noboru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Taruta,  Seiichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Saito,  Naoto"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-09-25"}],"displaytype":"detail","filename":"H23Kou906_Ogihara.pdf","filesize":[{"value":"2.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"H23Kou906_Ogihara.pdf","url":"https://soar-ir.repo.nii.ac.jp/record/7199/files/H23Kou906_Ogihara.pdf"},"version_id":"7380dc40-95be-4101-b189-09bbc19ea95a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"alumina ceramic","subitem_subject_scheme":"Other"},{"subitem_subject":"biocompatibility","subitem_subject_scheme":"Other"},{"subitem_subject":"bone tissue","subitem_subject_scheme":"Other"},{"subitem_subject":"carbon nanotube","subitem_subject_scheme":"Other"},{"subitem_subject":"cell attachment","subitem_subject_scheme":"Other"},{"subitem_subject":"composite; safety","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Biocompatibility and bone tissue compatibility of alumina ceramics reinforced with carbon nanotubes","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Biocompatibility and bone tissue compatibility of alumina ceramics reinforced with carbon nanotubes","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["849"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2012-10-02"},"publish_date":"2012-10-02","publish_status":"0","recid":"7199","relation_version_is_last":true,"title":["Biocompatibility and bone tissue compatibility of alumina ceramics reinforced with carbon nanotubes"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-12-14T03:54:11.913734+00:00"}