@article{oai:soar-ir.repo.nii.ac.jp:00008052, author = {Kobayashi, Tatsuya and Sakai, Keiichi and Tada, Tsuyoshi and Sekiguchi, Yasuyuki and Hara, Yosuke and Kodama, Kunihiko and Goto, Tetsuya and Tanaka, Yuichiro and Sano, Kenji and Nakayama, Jun and Hongo, Kazuhiro}, issue = {9}, journal = {JOURNAL OF CLINICAL NEUROSCIENCE}, month = {Sep}, note = {We report a 67-year-old woman who was diagnosed with a gliosarcoma at a second operation after diagnosis of a fibrillary astrocytoma 5 months previously. Initially, she underwent a CT-guided stereotactic biopsy. Histological examination showed fibrillary astrocytoma (World Health Organization [WHO] grade II). Loss of heterozygosity (LOH) on 1 p, 10q, and 19q was not detected. She received chemotherapy, but no radiotherapy. Five months after the biopsy, MRI revealed rapid tumor growth. Tissue obtained from partial removal of the tumor revealed gliosarcoma (WHO grade IV), and LOH on 10q and 19q was detected. The history, histopathology, and genetic alterations of this patient are discussed., Article, JOURNAL OF CLINICAL NEUROSCIENCE. 18(9):1251-1254 (2011)}, pages = {1251--1254}, title = {Gliosarcoma arising from a fibrillary astrocytoma}, volume = {18}, year = {2011} }