@article{oai:soar-ir.repo.nii.ac.jp:00008057, author = {Matsuda, Masayuki and Katoh, Nagaaki and Tazawa, Ko-Ichi and Shimojima, Yasuhiro and Mishima, Yoshito and Sano, Kenji and Ikeda, Shu-Ichi}, issue = {2}, journal = {AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS}, month = {Jun}, note = {We report a patient with primary systemic AL amyloidosis who suffered from remarkable bilateral cervical lymphadenopathy. Intensive chemotherapies, including two cycles of high-dose melphalan with autologous peripheral blood stem cell transplantation, were insufficiently effective for both the lymphadenopathy and amyloidogenic IgG lambda lambda-type M-protein in serum, but the patient showed complete haematological remission after extensive surgical removal of enlarged lymph nodes that had massive depositions of lambda lambda-type immunoglobulin light chain-derived amyloid. Lymphadenectomy may be a possible therapeutic approach with regard to both cosmetic and haematological aspects in primary systemic AL amyloidosis patients with focal lymphadenopathy., Article, AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS. 18(2):79-82 (2011)}, pages = {79--82}, title = {Surgical removal of amyloid-laden lymph nodes: a possible therapeutic approach in a primary systemic AL amyloidosis patient with focal lymphadenopathy}, volume = {18}, year = {2011} }