{"created":"2021-03-01T06:11:55.751094+00:00","id":8073,"links":{},"metadata":{"_buckets":{"deposit":"01f51605-6112-4375-bb9f-e6137bcf4d0b"},"_deposit":{"id":"8073","owners":[],"pid":{"revision_id":0,"type":"depid","value":"8073"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:00008073","sets":["882:883"]},"author_link":["22438","22439","22440","22441","22442","22443","22444","22445","22446","22447"],"item_1628147817048":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"261","bibliographicPageStart":"259","bibliographicVolumeNumber":"55","bibliographic_titles":[{"bibliographic_title":"JOURNAL OF HUMAN GENETICS"}]}]},"item_6_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Fabry's disease is an X-linked lysosomal storage disorder resulting from alpha-galactosidase A deficiency. Although ischemic stroke is recognized as an important manifestation of Fabry's disease, hemorrhagic stroke is considered to be rare. Here, we report our recent clinical experience with three hemizygous male patients with Fabry's disease who developed cerebral hemorrhage. One patient had classic type Fabry's disease with p.Ala37Val mutation and others had cerebrovascular variant with p.Glu66Gln mutation. Degeneration of the cerebral small arteries secondary to deposition of glycosphingolipids and aging, in addition to hypertension and antiplatelet/anticoagulant agents, are considered to be contributing factors for hemorrhage. Fabry's disease is frequently associated with not only ischemic but also hemorrhagic stroke, especially in elderly patients. Journal of Human Genetics ( 2010) 55, 259-261; doi:10.1038/jhg.2010.18; published online 19 March 2010","subitem_description_type":"Abstract"}]},"item_6_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_6_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"JOURNAL OF HUMAN GENETICS. 55(4):259-261 (2010)","subitem_description_type":"Other"}]},"item_6_link_3":{"attribute_name":"信州大学研究者総覧へのリンク","attribute_value_mlt":[{"subitem_link_text":"Sekijima, Yoshiki","subitem_link_url":"https://soar-rd.shinshu-u.ac.jp/profile/ja.WhLNuakh.html"},{"subitem_link_text":"Fukushima, Yoshimitsu","subitem_link_url":"https://soar-rd.shinshu-u.ac.jp/profile/ja.OUnVuUkh.html"}]},"item_6_link_67":{"attribute_name":"WoS","attribute_value_mlt":[{"subitem_link_url":"http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000277017900013"}]},"item_6_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"NATURE PUBLISHING GROUP"}]},"item_6_relation_47":{"attribute_name":"PubMed","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"20300124"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://pubmed.ncbi.nlm.nih.gov/20300124","subitem_relation_type_select":"PMID"}}]},"item_6_relation_48":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1038/jhg.2010.18"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1038/jhg.2010.18","subitem_relation_type_select":"DOI"}}]},"item_6_rights_62":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright© 2010 The Japan Society of Human Genetics"}]},"item_6_source_id_35":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1434-5161","subitem_source_identifier_type":"EISSN"}]},"item_6_source_id_40":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11206160","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakamura,  Katsuya","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sekijima,  Yoshiki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakamura,  Kimitoshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hattori,  Kiyoko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagamatsu,  Kiyoshiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimizu,  Yusaku","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ushiyama,  Masao","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Endo,  Fumio","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fukushima,  Yoshimitsu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ikeda,  Shu-ichi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-09-25"}],"displaytype":"detail","filename":"Cerebral_hemorrhage_Fabry_disease.pdf","filesize":[{"value":"735.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Cerebral_hemorrhage_Fabry_disease.pdf","url":"https://soar-ir.repo.nii.ac.jp/record/8073/files/Cerebral_hemorrhage_Fabry_disease.pdf"},"version_id":"a62249c4-704e-484a-827d-197b23400212"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"alpha-galactosidase A","subitem_subject_scheme":"Other"},{"subitem_subject":"Fabry's disease","subitem_subject_scheme":"Other"},{"subitem_subject":"cerebral hemorrhage","subitem_subject_scheme":"Other"},{"subitem_subject":"cerebral infarction","subitem_subject_scheme":"Other"},{"subitem_subject":"stroke","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Cerebral hemorrhage in Fabry's disease","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Cerebral hemorrhage in Fabry's disease","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["883"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2013-04-01"},"publish_date":"2013-04-01","publish_status":"0","recid":"8073","relation_version_is_last":true,"title":["Cerebral hemorrhage in Fabry's disease"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-12-14T04:00:49.102482+00:00"}