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In addition, hypoxia reduces I-123-MIBG transport in pulmonary endothelial cells in vitro. The present study was undertaken to evaluate I-123-MIBG uptake in the lungs of patients with high-altitude pulmonary oedema (HAPE). Methods: I-123-MIBG scintigraphy was performed in eight patients with HAPE. The findings were compared with those in 24 patients with congestive heart failure due to idiopathic dilated cardiomyopathy (DCM) and in 13 normal control subjects. In patients with HAPE, the I-123-MIBG examination was performed 7-14 days after admission. Anterior planar images were acquired 15 min after injection of I-123-MIBG and the total lung to upper mediastinum ratio (L/M ratio) was calculated for both lungs. Results: The L/M ratio in patients with HAPE (1.39 +/- 0.15, mean +/- SD) was significantly lower than in those with congestive heart failure/DCM (1.66 +/- 0.16) or in normal controls (1.53 +/- 0.14). There were no significant differences among the groups in I-123-MIBG accumulation in the heart. Conclusions: Although the mechanism of altered I-123-MIBG kinetics in HAPE remains obscure, decreased I-123-MIBG uptake in the lungs may potentially be a suitable technique for the assessment of pathological conditions associated with the pulmonary endothelium."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Urushihata,  K", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "22578", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Koizumi,  T", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "22579", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hanaoka,  M", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "22580", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Fujimoto,  K", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "22581", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kubo,  K", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "22582", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kobayashi,  T", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "22583", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Fujii,  T", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "22584", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-25"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "RESPIROLOGY-K.pdf", "filesize": [{"value": "586.2 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 586200.0, "url": {"label": "RESPIROLOGY-K.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/8092/files/RESPIROLOGY-K.pdf"}, "version_id": "fc7487da-5398-41ad-bddf-dbe9619d0e45"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Reduced lung uptake of iodine-123 metaiodobenzylguanidine in high-altitude pulmonary oedema", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Reduced lung uptake of iodine-123 metaiodobenzylguanidine in high-altitude pulmonary oedema", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["883"], "permalink_uri": "http://hdl.handle.net/10091/1382", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2008-10-29"}, "publish_date": "2008-10-29", "publish_status": "0", "recid": "8092", "relation": {}, "relation_version_is_last": true, "title": ["Reduced lung uptake of iodine-123 metaiodobenzylguanidine in high-altitude pulmonary oedema"], "weko_shared_id": -1}
  1. 055 医学部附属病院
  2. 0551 学術論文

Reduced lung uptake of iodine-123 metaiodobenzylguanidine in high-altitude pulmonary oedema

http://hdl.handle.net/10091/1382
http://hdl.handle.net/10091/1382
1f4f9b0e-8bc4-4dea-a31b-1e9af9e0370c
名前 / ファイル ライセンス アクション
RESPIROLOGY-K.pdf RESPIROLOGY-K.pdf (586.2 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2008-10-29
タイトル
言語 en
タイトル Reduced lung uptake of iodine-123 metaiodobenzylguanidine in high-altitude pulmonary oedema
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Urushihata, K

× Urushihata, K

WEKO 22578

en Urushihata, K

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Koizumi, T

× Koizumi, T

WEKO 22579

en Koizumi, T

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Hanaoka, M

× Hanaoka, M

WEKO 22580

en Hanaoka, M

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Fujimoto, K

× Fujimoto, K

WEKO 22581

en Fujimoto, K

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Kubo, K

× Kubo, K

WEKO 22582

en Kubo, K

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Kobayashi, T

× Kobayashi, T

WEKO 22583

en Kobayashi, T

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Fujii, T

× Fujii, T

WEKO 22584

en Fujii, T

Search repository
信州大学研究者総覧へのリンク
氏名 Urushihata, K
URL https://soar-rd.shinshu-u.ac.jp/profile/ja.jakhHVkh.html
信州大学研究者総覧へのリンク
氏名 Koizumi, T
URL https://soar-rd.shinshu-u.ac.jp/profile/ja.WakmHhkh.html
信州大学研究者総覧へのリンク
氏名 Hanaoka, M
URL https://soar-rd.shinshu-u.ac.jp/profile/ja.yCLmHVkh.html
信州大学研究者総覧へのリンク
氏名 Fujimoto, K
URL https://soar-rd.shinshu-u.ac.jp/profile/ja.yFfaHFkh.html
出版者
出版者 BLACKWELL PUBLISHING
引用
内容記述タイプ Other
内容記述 RESPIROLOGY. 13(6):897-902(2008)
書誌情報 RESPIROLOGY

巻 13, 号 6, p. 897-902, 発行日 2008-09
内容記述
内容記述タイプ Other
内容記述 The definitive version is available at www.blackwell-synergy.com.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 1323-7799
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA11097269
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1111/j.1440-1843.2008.01343.x
関連名称 10.1111/j.1440-1843.2008.01343.x
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000259220800020
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