Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2015-06-02 |
タイトル |
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タイトル |
Suppressive Effect of Wild Saccharomyces cerevisiae and Saccharomyces paradoxus Strains on Ige Production by Mouse Spleen Cells |
言語 |
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言語 |
eng |
DOI |
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関連識別子 |
https://doi.org/10.3136/fstr.19.1019 |
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関連名称 |
10.3136/fstr.19.1019 |
キーワード |
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主題 |
Saccharomyces cerevisiae, Saccharomyces paradoxus, wild yeast, IFN-gamma, IL-12, IgE, allergy |
資源タイプ |
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資源 |
http://purl.org/coar/resource_type/c_6501 |
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タイプ |
journal article |
著者 |
Kawahara, Takeshi
Nakayama, Daichi
Toda, Keisuke
Inagaki, Shyuichiro
Tanaka, Katsumi
Yasui, Hisako
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信州大学研究者総覧へのリンク |
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氏名 |
Kawahara, Takeshi |
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URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.OVymPUkh.html |
出版者 |
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出版者 |
KARGER |
引用 |
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内容記述 |
FOOD SCIENCE AND TECHNOLOGY RESEARCH. 19(6):1019-1027 (2013) |
書誌情報 |
FOOD SCIENCE AND TECHNOLOGY RESEARCH
巻 19,
号 6,
p. 1019-1027,
発行日 2013-11
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抄録 |
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内容記述 |
The genus Saccharomyces includes industrial yeasts that are used for bread and alcoholic beverage production. Saccharomyces strains isolated from natural resources, referred to as “wild” yeasts, are used for making products with strain-specific flavors that are different from those of the “domesticated” industrial yeasts. The physiological effects of wild yeast are poorly understood. In this study, we isolated 2 Saccharomyces cerevisiae strains (S02 − 03) and 5 Saccharomyces paradoxus strains (P01 − 02, S01, S04 − 05) from natural resources in the Kiso area and investigated the effect of these fungal strains on IgE production by mouse spleen cells. Culturing spleen cells with heat-killed yeasts resulted in elevated IFN-γ and IL-12 levels followed by significant reduction in IgE levels. The S03 and P01 strains induced IL-12 p40 and IL-10 expression in RAW264 cells. Thus, wild strains of S. cerevisiae and S. paradoxus regulate macrophage cytokine production to improve the Th1/Th2 immune balance and suppress IgE production. |
資源タイプ(コンテンツの種類) |
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内容記述 |
Article |
ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
1344-6606 |
書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA11320122 |
権利 |
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権利情報 |
Copyright (c) 2013 Japanese Society for Food Science and Technology |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
WoS |
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URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000328714000014 |