WEKO3
アイテム
{"_buckets": {"deposit": "8a883b36-989f-44c0-a38b-9de0df096e91"}, "_deposit": {"id": "10238", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "10238"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00010238", "sets": ["1017"]}, "author_link": ["32311", "32312", "32313", "32314", "32315", "32316", "32317", "32318"], "item_1628147817048": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_6_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2014-01", "bibliographicIssueDateType": "Issued"}, "bibliographicPageStart": "393598", "bibliographicVolumeNumber": "2014", "bibliographic_titles": [{"bibliographic_title": "BIOMED RESEARCH INTERNATIONAL"}]}]}, "item_6_description_20": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Previous studies showed that hydrolysates of beta-lactoglobulin (BLG) prepared using gastrointestinal proteases strongly inhibit dipeptidyl peptidase-IV (DPP-IV) activity in vitro. In this study, we developed a BLG-secreting Lactococcus lactis strain as a delivery vehicle and in situ expression system. Interestingly, trypsin-digested recombinant BLG from L. lactis inhibited DPP-IV activity, suggesting that BLG-secreting L. lactis may be useful in the treatment of type 2 diabetes mellitus.", "subitem_description_type": "Abstract"}]}, "item_6_description_30": {"attribute_name": "資源タイプ(コンテンツの種類)", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "BIOMED RESEARCH INTERNATIONAL. 2014:393598 (2014)", "subitem_description_type": "Other"}]}, "item_6_link_3": {"attribute_name": "信州大学研究者総覧へのリンク", "attribute_value_mlt": [{"subitem_link_text": "Uyeno, Yutaka", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.gFAaPUkh.html"}, {"subitem_link_text": "Shimosato, Takeshi", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.ONLCjFkV.html"}]}, "item_6_link_67": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000340376600001"}]}, "item_6_publisher_4": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "HINDAWI PUBLISHING CORPORATION"}]}, "item_6_relation_48": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1155/2014/393598"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1155/2014/393598", "subitem_relation_type_select": "DOI"}}]}, "item_6_rights_62": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright© 2014 Suguru Shigemori et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited."}]}, "item_6_select_64": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_6_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2314-6133", "subitem_source_identifier_type": "PISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2314-6133", "subitem_source_identifier_type": "PISSN"}]}, "item_6_text_70": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "GENE-EXPRESSION SYSTEM; ACID BACTERIA; LACTOBACILLUS-PLANTARUM; THERAPEUTIC PROTEINS; MUCOSAL DELIVERY; POLLEN ALLERGEN; NISIN; CELL; OLIGODEOXYNUCLEOTIDE; RESPONSES"}]}, "item_6_textarea_68": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "Previous studies showed that hydrolysates of beta-lactoglobulin (BLG) prepared using gastrointestinal proteases strongly inhibit dipeptidyl peptidase-IV (DPP-IV) activity in vitro. In this study, we developed a BLG-secreting Lactococcus lactis strain as a delivery vehicle and in situ expression system. Interestingly, trypsin-digested recombinant BLG from L. lactis inhibited DPP-IV activity, suggesting that BLG-secreting L. lactis may be useful in the treatment of type 2 diabetes mellitus."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Shigemori, Suguru", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "32311", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Oshiro, Kazushi", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "32312", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Wang, Pengfei", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "32313", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamamoto, Yoshinari", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "32314", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Wang, Yeqin", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "32315", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sato, Takashi", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "32316", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Uyeno, Yutaka", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "32317", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shimosato, Takeshi", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "32318", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-25"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Generation_Dipeptidyl_Peptidase-IV-Inhibiting_Peptides.pdf", "filesize": [{"value": "2.2 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 2200000.0, "url": {"label": "Generation_Dipeptidyl_Peptidase-IV-Inhibiting_Peptides.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/10238/files/Generation_Dipeptidyl_Peptidase-IV-Inhibiting_Peptides.pdf"}, "version_id": "31c8351f-28c5-47a7-a6b7-13234f97fe4b"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Generation of Dipeptidyl Peptidase-IV-Inhibiting Peptides from beta-Lactoglobulin Secreted by Lactococcus lactis", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Generation of Dipeptidyl Peptidase-IV-Inhibiting Peptides from beta-Lactoglobulin Secreted by Lactococcus lactis", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["1017"], "permalink_uri": "http://hdl.handle.net/10091/18081", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2015-02-12"}, "publish_date": "2015-02-12", "publish_status": "0", "recid": "10238", "relation": {}, "relation_version_is_last": true, "title": ["Generation of Dipeptidyl Peptidase-IV-Inhibiting Peptides from beta-Lactoglobulin Secreted by Lactococcus lactis"], "weko_shared_id": -1}
Generation of Dipeptidyl Peptidase-IV-Inhibiting Peptides from beta-Lactoglobulin Secreted by Lactococcus lactis
http://hdl.handle.net/10091/18081
http://hdl.handle.net/10091/1808167a263c8-08eb-4848-9c1b-26d7f46d81fe
名前 / ファイル | ライセンス | アクション |
---|---|---|
Generation_Dipeptidyl_Peptidase-IV-Inhibiting_Peptides.pdf (2.2 MB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2015-02-12 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Generation of Dipeptidyl Peptidase-IV-Inhibiting Peptides from beta-Lactoglobulin Secreted by Lactococcus lactis | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Shigemori, Suguru
× Shigemori, Suguru× Oshiro, Kazushi× Wang, Pengfei× Yamamoto, Yoshinari× Wang, Yeqin× Sato, Takashi× Uyeno, Yutaka× Shimosato, Takeshi |
|||||
信州大学研究者総覧へのリンク | ||||||
氏名 | Uyeno, Yutaka | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.gFAaPUkh.html | |||||
信州大学研究者総覧へのリンク | ||||||
氏名 | Shimosato, Takeshi | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.ONLCjFkV.html | |||||
出版者 | ||||||
出版者 | HINDAWI PUBLISHING CORPORATION | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | BIOMED RESEARCH INTERNATIONAL. 2014:393598 (2014) | |||||
書誌情報 |
BIOMED RESEARCH INTERNATIONAL 巻 2014, p. 393598, 発行日 2014-01 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Previous studies showed that hydrolysates of beta-lactoglobulin (BLG) prepared using gastrointestinal proteases strongly inhibit dipeptidyl peptidase-IV (DPP-IV) activity in vitro. In this study, we developed a BLG-secreting Lactococcus lactis strain as a delivery vehicle and in situ expression system. Interestingly, trypsin-digested recombinant BLG from L. lactis inhibited DPP-IV activity, suggesting that BLG-secreting L. lactis may be useful in the treatment of type 2 diabetes mellitus. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 2314-6133 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1155/2014/393598 | |||||
関連名称 | 10.1155/2014/393598 | |||||
権利 | ||||||
権利情報 | Copyright© 2014 Suguru Shigemori et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000340376600001 |