| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2015-02-12 |
| タイトル |
|
|
タイトル |
Generation of Dipeptidyl Peptidase-IV-Inhibiting Peptides from beta-Lactoglobulin Secreted by Lactococcus lactis |
| 言語 |
|
|
言語 |
eng |
| DOI |
|
|
|
関連識別子 |
https://doi.org/10.1155/2014/393598 |
|
|
関連名称 |
10.1155/2014/393598 |
| 資源タイプ |
|
|
資源 |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 著者 |
Shigemori, Suguru
Oshiro, Kazushi
Wang, Pengfei
Yamamoto, Yoshinari
Wang, Yeqin
Sato, Takashi
Uyeno, Yutaka
Shimosato, Takeshi
|
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Uyeno, Yutaka |
|
URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.gFAaPUkh.html |
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Shimosato, Takeshi |
|
URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.ONLCjFkV.html |
| 出版者 |
|
|
出版者 |
HINDAWI PUBLISHING CORPORATION |
| 引用 |
|
|
内容記述 |
BIOMED RESEARCH INTERNATIONAL. 2014:393598 (2014) |
| 書誌情報 |
BIOMED RESEARCH INTERNATIONAL
巻 2014,
p. 393598,
発行日 2014-01
|
| 抄録 |
|
|
内容記述 |
Previous studies showed that hydrolysates of beta-lactoglobulin (BLG) prepared using gastrointestinal proteases strongly inhibit dipeptidyl peptidase-IV (DPP-IV) activity in vitro. In this study, we developed a BLG-secreting Lactococcus lactis strain as a delivery vehicle and in situ expression system. Interestingly, trypsin-digested recombinant BLG from L. lactis inhibited DPP-IV activity, suggesting that BLG-secreting L. lactis may be useful in the treatment of type 2 diabetes mellitus. |
| 資源タイプ（コンテンツの種類） |
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| ISSN |
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収録物識別子タイプ |
PISSN |
|
収録物識別子 |
2314-6133 |
| 権利 |
|
|
権利情報 |
Copyright© 2014 Suguru Shigemori et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| WoS |
|
|
URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000340376600001 |
Generation_Dipeptidyl_Peptidase-IV-Inhibiting_Peptides.pdf (2.2 MB)
