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  1. 070 農学部, 大学院農学研究科
  2. 0701 学術論文

Ultrastructural Study on Colocalization of Glucagon-Like Peptide (GLP)-1 with GLP-2 in Chicken Intestinal L-Cells

http://hdl.handle.net/10091/17855
962c0ce5-bc5d-44eb-a888-2e97726c4ba9
名前 / ファイル ライセンス アクション
Ultrastructural_Study_Colocalization_Glucagon-Like_Peptide.pdf Ultrastructural_Study_Colocalization_Glucagon-Like_Peptide.pdf (1.9 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-09-05
タイトル
言語 en
タイトル Ultrastructural Study on Colocalization of Glucagon-Like Peptide (GLP)-1 with GLP-2 in Chicken Intestinal L-Cells
言語
言語 eng
キーワード
主題Scheme Other
主題 chicken
キーワード
主題Scheme Other
主題 glucagon-like peptides
キーワード
主題Scheme Other
主題 immunocytochemistry
キーワード
主題Scheme Other
主題 immunohistochemistry
キーワード
主題Scheme Other
主題 small intestine
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Nishimura, Kei

× Nishimura, Kei

WEKO 32352

ja Nishimura, Kei

Search repository
Hiramatsu, Kohzy

× Hiramatsu, Kohzy

WEKO 32353

ja Hiramatsu, Kohzy

Search repository
Monir, Mohammad M.

× Monir, Mohammad M.

WEKO 32354

ja Monir, Mohammad M.

Search repository
Takemoto, Chihiro

× Takemoto, Chihiro

WEKO 32355

ja Takemoto, Chihiro

Search repository
Watanabe, Takafumi

× Watanabe, Takafumi

WEKO 32356

ja Watanabe, Takafumi

Search repository
信州大学研究者総覧へのリンク
氏名 Hiramatsu, Kohzy
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.yeTmPpkh.html
出版者
出版者 JAPAN SOC VET SCI
引用
内容記述タイプ Other
内容記述 JOURNAL OF VETERINARY MEDICAL SCIENCE. 75(10):1335-1339 (2013)
書誌情報 JOURNAL OF VETERINARY MEDICAL SCIENCE

巻 75, 号 10, p. 1335-1339, 発行日 2013-10
抄録
内容記述タイプ Abstract
内容記述 Colocalization of glucagon-like peptide (GLP)-1 with GLP-2 in L-cells was investigated in the chicken ileum by using double immunofluorescent and immunocytochemical techniques. Ultrastructural features of L-cells were also clarified in this study. L-cells showing immunoreactivity for both GLP-1 and GLP-2 were distributed in the whole ileum. They showed comma-like or flask-like shape and were located in epithelium of crypts and lower part of intestinal villi. L-cells showing GLP-1-immunoreactivity only were found in epithelium of lower and middle parts of intestinal villi. Transmission electron microscopy indicated that L-cells identified by colloidal gold-labeled immunocytochemistry were covered apically with microvilli, open-type and contained many secretory granules in their perikarya. These secretory granules without halo were round to oval in shape and showed moderate electron density. The longest and shortest diameters of secretory granules were 355 +/- 62 nm (mean +/- SD) and 287 +/- 48 nm, respectively. Double labeling immunocytochemistry using two different sizes of particles (6 and 12 nm in diameter) of colloidal gold revealed that GLP-1 colocalized with GLP-2 in the same secretory granules. This study advances new morphological data about the endocrine system of the chicken small intestine.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 0916-7250
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA10796138
PubMed
関連識別子
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/23759686/
関連名称
関連名称 23759686
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1292/jvms.13-0106
関連名称
関連名称 10.1292/jvms.13-0106
権利
権利情報 Copyright© 2013 The Japanese Society of Veterinary Science
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000326850900010
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