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  1. 070 農学部, 大学院農学研究科
  2. 0701 学術論文

Fermented Soybean Powder with Rice Mold in the Absence of Salt Stimulates the Cellular Immune System and Suppresses the Humoral Immune Response in Mice

http://hdl.handle.net/10091/17804
46f7c295-9c5f-4290-be5d-22ae762f3823
名前 / ファイル ライセンス アクション
Fermented_Soybean_Powder_Rice_Mold.pdf Fermented_Soybean_Powder_Rice_Mold.pdf (748.7 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-08-06
タイトル
言語 en
タイトル Fermented Soybean Powder with Rice Mold in the Absence of Salt Stimulates the Cellular Immune System and Suppresses the Humoral Immune Response in Mice
言語
言語 eng
キーワード
主題Scheme Other
主題 fermented soybean
キーワード
主題Scheme Other
主題 immunomodulation
キーワード
主題Scheme Other
主題 cellular immune response
キーワード
主題Scheme Other
主題 antibody production
キーワード
主題Scheme Other
主題 mouse
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Karasawa, Koji

× Karasawa, Koji

WEKO 32444

Karasawa, Koji

Search repository
Sugiura, Yoko

× Sugiura, Yoko

WEKO 32445

Sugiura, Yoko

Search repository
Kojima, Masaaki

× Kojima, Masaaki

WEKO 32446

Kojima, Masaaki

Search repository
Uzuhashi, Yuji

× Uzuhashi, Yuji

WEKO 32447

Uzuhashi, Yuji

Search repository
Otani, Hajime

× Otani, Hajime

WEKO 32448

Otani, Hajime

Search repository
出版者
出版者 CENTER ACADEMIC PUBL JAPAN
引用
内容記述タイプ Other
内容記述 JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY. 59(6):564-569 (2013)
書誌情報 JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

巻 59, 号 6, p. 564-569, 発行日 2013-12
抄録
内容記述タイプ Abstract
内容記述 The immunomodulatory effect of fermented non-salty soybean powder (NSBP) was investigated in C3H/HeN mice. The number of splenic CD11b(+), CD49b(+), and interferon (IFN)-gamma(+)CD4(+) cells increased significantly, while that of interleukin (IL)-4(+)CD4(+) and CD19(+) cells decreased significantly in cultures containing NSBP. Similarly, in the spleen and Peyer's patches of mice fed a diet containing NSBP, the number of IL-12(+)CD11b(+), CD49b(+), and IFN-gamma(+)CD4(+) cells increased noticeably, whereas the number of splenic IL-4(+)CD4(+) and CD19b(+) cells was lower compared to mice fed an NSBP-free diet. Superoxide production by peritoneal macrophages was significantly higher in mice fed an NSBP-containing diet. Both intestinal total IgA and serum total IgG levels declined in mice fed the NSBP-containing diet. Microarray analysis of mRNAs extracted from Peyer's patch cells of mice fed the NSBP-containing diet indicated an increase in the expression of several genes related to cellular immune responses, while the expression of genes related to immunoglobulin production decreased. These results indicate that NSBP stimulates the cellular immune response, but suppresses the acquired humoral immune response in C3H/HeN mice.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ ISSN
収録物識別子 0301-4800
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00703822
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.3177/jnsv.59.564
関連名称
関連名称 10.3177/jnsv.59.564
権利
権利情報 Copyright© 2013 the Center for Academic Publications Japan
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000329383800013
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