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Fermented Soybean Powder with Rice Mold in the Absence of Salt Stimulates the Cellular Immune System and Suppresses the Humoral Immune Response in Mice
http://hdl.handle.net/10091/17804
http://hdl.handle.net/10091/1780446f7c295-9c5f-4290-be5d-22ae762f3823
| 名前 / ファイル | ライセンス | アクション |
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Fermented_Soybean_Powder_Rice_Mold.pdf (748.7 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||
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| 公開日 | 2014-08-06 | |||||||||||||||
| タイトル | ||||||||||||||||
| タイトル | Fermented Soybean Powder with Rice Mold in the Absence of Salt Stimulates the Cellular Immune System and Suppresses the Humoral Immune Response in Mice | |||||||||||||||
| 言語 | ||||||||||||||||
| 言語 | eng | |||||||||||||||
| DOI | ||||||||||||||||
| 関連識別子 | https://doi.org/10.3177/jnsv.59.564 | |||||||||||||||
| 関連名称 | 10.3177/jnsv.59.564 | |||||||||||||||
| キーワード | ||||||||||||||||
| 主題 | fermented soybean, immunomodulation, cellular immune response, antibody production, mouse | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||
| タイプ | journal article | |||||||||||||||
| 著者 |
Karasawa, Koji
× Karasawa, Koji
× Sugiura, Yoko
× Kojima, Masaaki
× Uzuhashi, Yuji
× Otani, Hajime
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| 出版者 | ||||||||||||||||
| 出版者 | CENTER ACADEMIC PUBL JAPAN | |||||||||||||||
| 引用 | ||||||||||||||||
| 内容記述 | JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY. 59(6):564-569 (2013) | |||||||||||||||
| 書誌情報 |
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY 巻 59, 号 6, p. 564-569, 発行日 2013-12 |
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| 抄録 | ||||||||||||||||
| 内容記述 | The immunomodulatory effect of fermented non-salty soybean powder (NSBP) was investigated in C3H/HeN mice. The number of splenic CD11b(+), CD49b(+), and interferon (IFN)-gamma(+)CD4(+) cells increased significantly, while that of interleukin (IL)-4(+)CD4(+) and CD19(+) cells decreased significantly in cultures containing NSBP. Similarly, in the spleen and Peyer's patches of mice fed a diet containing NSBP, the number of IL-12(+)CD11b(+), CD49b(+), and IFN-gamma(+)CD4(+) cells increased noticeably, whereas the number of splenic IL-4(+)CD4(+) and CD19b(+) cells was lower compared to mice fed an NSBP-free diet. Superoxide production by peritoneal macrophages was significantly higher in mice fed an NSBP-containing diet. Both intestinal total IgA and serum total IgG levels declined in mice fed the NSBP-containing diet. Microarray analysis of mRNAs extracted from Peyer's patch cells of mice fed the NSBP-containing diet indicated an increase in the expression of several genes related to cellular immune responses, while the expression of genes related to immunoglobulin production decreased. These results indicate that NSBP stimulates the cellular immune response, but suppresses the acquired humoral immune response in C3H/HeN mice. | |||||||||||||||
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| ISSN | ||||||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||||||
| 収録物識別子 | 0301-4800 | |||||||||||||||
| 書誌レコードID | ||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||
| 収録物識別子 | AA00703822 | |||||||||||||||
| 権利 | ||||||||||||||||
| 権利情報 | Copyright© 2013 the Center for Academic Publications Japan | |||||||||||||||
| 出版タイプ | ||||||||||||||||
| 出版タイプ | AM | |||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||||
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| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000329383800013 | |||||||||||||||
