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  1. 070 農学部, 大学院農学研究科
  2. 0701 学術論文

Blood-pressure-lowering effect of fermented buckwheat sprouts in spontaneously hypertensive rats

http://hdl.handle.net/10091/17102
36d04e96-9629-4e60-8a65-211b68d4cc0b
名前 / ファイル ライセンス アクション
Blood-pressure-lowering_Effect_Fermented_Buckwheat_Sprouts.pdf Blood-pressure-lowering_Effect_Fermented_Buckwheat_Sprouts.pdf (671.4 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2013-08-27
タイトル
言語 en
タイトル Blood-pressure-lowering effect of fermented buckwheat sprouts in spontaneously hypertensive rats
言語
言語 eng
キーワード
主題Scheme Other
主題 Antihypertension
キーワード
主題Scheme Other
主題 Vasorelaxation
キーワード
主題Scheme Other
主題 Fermented buckwheat sprouts
キーワード
主題Scheme Other
主題 Blood pressure
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Nakamura, Kozo

× Nakamura, Kozo

WEKO 32504

Nakamura, Kozo

Search repository
Naramoto, Kyoko

× Naramoto, Kyoko

WEKO 32505

Naramoto, Kyoko

Search repository
Koyama, Masahiro

× Koyama, Masahiro

WEKO 32506

Koyama, Masahiro

Search repository
信州大学研究者総覧へのリンク
氏名 Nakamura, Kozo
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.upyCPUkh.html
出版者
出版者 ELSEVIER SCIENCE BV
引用
内容記述タイプ Other
内容記述 JOURNAL OF FUNCTIONAL FOODS. 5(1):406-415 (2013)
書誌情報 JOURNAL OF FUNCTIONAL FOODS

巻 5, 号 1, p. 406-415, 発行日 2013-01
抄録
内容記述タイプ Abstract
内容記述 A practical antihypertensive food, neo-fermented buckwheat sprouts (neo-FBS), was produced from buckwheat sprouts by lactic fermentation. The neo-FBS preparation gave a 12.7 times better yield and had a 10 times more potent blood-pressure-lowering (BPL) effect than conventionally prepared products. Neo-FBS decreased both systolic and diastolic blood pressure in spontaneously hypertensive rats (SHRs) at a dose of 0.010 mg/kg, an effect comparable to 1.0 mg/kg captopril, an anti-hypertensive drug. Orally administered neo-FBS (10 mg/kg) significantly decreased angiotensin I-converting enzyme (ACE) activity in the lung, thoracic aorta, heart, kidney, and liver of SHRs. Neo-FBS had a detectable relaxing effect on a phenylephrine-precontracted thoracic aorta in SHRs at 0.5 mu g/mL and the EC50 value was 8.3 +/- 1.4 mu g/mL. The ACE inhibition and vasorelaxation activities were found to be responsible for the excellent BPL effect of neo-FBS. As SHR is a standard model for human hypertension, neo-FBS may also have BPL effects in human patients.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ ISSN
収録物識別子 1756-4646
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.jff.2012.11.013
関連名称
関連名称 10.1016/j.jff.2012.11.013
権利
権利情報 Copyright© 2012 Elsevier Ltd. All rights reserved.
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000315241500048
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