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Inhibitory effect of hot-water extract of quince (Cydonia oblonga) on immunoglobulin E-dependent late-phase immune reactions of mast cells
http://hdl.handle.net/10091/16132
http://hdl.handle.net/10091/161320afeb339-652b-4d3a-b35e-f62c52786e03
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2012-12-06 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Inhibitory effect of hot-water extract of quince (Cydonia oblonga) on immunoglobulin E-dependent late-phase immune reactions of mast cells | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Quince | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Mast cell | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Late-phase reaction | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Leukotriene C(4) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Prostaglandin D(2) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cyclooxygenase | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Kawahara, Takeshi
× Kawahara, Takeshi× Iizuka, Tatsuhiro |
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信州大学研究者総覧へのリンク | ||||||
氏名 | Kawahara, Takeshi | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.OVymPUkh.html | |||||
出版者 | ||||||
出版者 | SPRINGER | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | CYTOTECHNOLOGY. 63(2):143-152 (2011) | |||||
書誌情報 |
CYTOTECHNOLOGY 巻 63, 号 2, p. 143-152, 発行日 2011-03 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We evaluated the effect of a crude hot-water extract (HW) of quince (Cydonia oblonga Miller) fruit on immunoglobulin E (IgE)-dependent late-phase immune reactions of mast cells using in vitro system. Mast cell-like RBL-2H3 cells were treated with quince HW and late-phase reaction was then induced by stimulation with IgE + Antigen. Quince HW reduced the elevation of interleukin-13 and tumor necrosis factor-alpha expression level. Furthermore, quince HW suppressed these cytokine expressions of mouse bone marrow-derived mast cells (BMMCs), a normal mast cell model. Leukotriene C(4) and prostaglandin D(2) production in BMMCs after 1 and 6 h of stimulation, respectively, were also reduced by treating the cells with quince HW. We found that the induction of intracellular cyclooxygenase (COX)-2 expression but not COX-1 expression in BMMCs was reduced by quince HW. These results suggest that quince HW has an inhibitory effect on broad range of the late-phase immune reactions of mast cells. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0920-9069 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10678299 | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | https://pubmed.ncbi.nlm.nih.gov/21264509/ | |||||
関連名称 | 21264509 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1007/s10616-010-9323-8 | |||||
関連名称 | 10.1007/s10616-010-9323-8 | |||||
権利 | ||||||
権利情報 | The final publication is available at www.springerlink.com | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000289798300006 |