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  1. 070 農学部, 大学院農学研究科
  2. 0701 学術論文

Inhibitory effect of hot-water extract of quince (Cydonia oblonga) on immunoglobulin E-dependent late-phase immune reactions of mast cells

http://hdl.handle.net/10091/16132
http://hdl.handle.net/10091/16132
0afeb339-652b-4d3a-b35e-f62c52786e03
名前 / ファイル ライセンス アクション
Inhibitory_effect_hot-water_extract_quince_Cydonia_oblonga.pdf Inhibitory_effect_hot-water_extract_quince_Cydonia_oblonga.pdf (240.6 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2012-12-06
タイトル
タイトル Inhibitory effect of hot-water extract of quince (Cydonia oblonga) on immunoglobulin E-dependent late-phase immune reactions of mast cells
言語
言語 eng
DOI
関連識別子 https://doi.org/10.1007/s10616-010-9323-8
関連名称 10.1007/s10616-010-9323-8
キーワード
主題 Quince, Mast cell, Late-phase reaction, Leukotriene C(4), Prostaglandin D(2), Cyclooxygenase
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Kawahara, Takeshi

× Kawahara, Takeshi

Kawahara, Takeshi

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Iizuka, Tatsuhiro

× Iizuka, Tatsuhiro

Iizuka, Tatsuhiro

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信州大学研究者総覧へのリンク
氏名 Kawahara, Takeshi
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.OVymPUkh.html
出版者
出版者 SPRINGER
引用
内容記述 CYTOTECHNOLOGY. 63(2):143-152 (2011)
書誌情報 CYTOTECHNOLOGY

巻 63, 号 2, p. 143-152, 発行日 2011-03
抄録
内容記述 We evaluated the effect of a crude hot-water extract (HW) of quince (Cydonia oblonga Miller) fruit on immunoglobulin E (IgE)-dependent late-phase immune reactions of mast cells using in vitro system. Mast cell-like RBL-2H3 cells were treated with quince HW and late-phase reaction was then induced by stimulation with IgE + Antigen. Quince HW reduced the elevation of interleukin-13 and tumor necrosis factor-alpha expression level. Furthermore, quince HW suppressed these cytokine expressions of mouse bone marrow-derived mast cells (BMMCs), a normal mast cell model. Leukotriene C(4) and prostaglandin D(2) production in BMMCs after 1 and 6 h of stimulation, respectively, were also reduced by treating the cells with quince HW. We found that the induction of intracellular cyclooxygenase (COX)-2 expression but not COX-1 expression in BMMCs was reduced by quince HW. These results suggest that quince HW has an inhibitory effect on broad range of the late-phase immune reactions of mast cells.
資源タイプ(コンテンツの種類)
ISSN
収録物識別子タイプ ISSN
収録物識別子 0920-9069
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA10678299
PubMed
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/21264509/
関連名称 21264509
権利
権利情報 The final publication is available at www.springerlink.com
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000289798300006
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Cite as

Kawahara, Takeshi, Iizuka, Tatsuhiro, 2011, Inhibitory effect of hot-water extract of quince (Cydonia oblonga) on immunoglobulin E-dependent late-phase immune reactions of mast cells: SPRINGER, 143–152 p.

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