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The results of deconjugation treatments indicated that glucose and sulfate combined with 1-hydroxypyrene. Further analysis by LC/ESI-MS/MS showed that the molecular weight of the product was 460 (m/z 459; deprotonated ion), and that it has a glucose-sulfate moiety (m/z 241; fragment ion). These results indicated that the new metabolite was the glucose-sulfate conjugate of 1-hydroxypyrene. The glucose-sulfate conjugate is a phase II product that has not been reported previously from any organism. Several studies have demonstrated that sulfation is an important pathway for metabolism of xenobiotics in aquatic invertebrates. Thus, glucose-sulfate conjugates may add an important signal for excretion or sequestration of xenobiotics for aquatic invertebrates. (C) 2007 Elsevier Inc. 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  1. 090 大学院理工学系研究科, 大学院総合工学系研究科
  2. 0901 学術論文

Glucose-sulfate conjugates as a new phase II metabolite formed by aquatic crustaceans

http://hdl.handle.net/10091/397
35fb19ae-48f9-4ee4-8aee-542ee615f4c7
名前 / ファイル ライセンス アクション
glucose-sulfate_conjugates.pdf glucose-sulfate_conjugates.pdf (238.6 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2007-10-29
タイトル
言語 en
タイトル Glucose-sulfate conjugates as a new phase II metabolite formed by aquatic crustaceans
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Ikenaka, Y

× Ikenaka, Y

WEKO 35602

Ikenaka, Y

Search repository
Ishizaka, M

× Ishizaka, M

WEKO 35603

Ishizaka, M

Search repository
Eun, H

× Eun, H

WEKO 35604

Eun, H

Search repository
Miyabara, Y

× Miyabara, Y

WEKO 35605

Miyabara, Y

Search repository
信州大学研究者総覧へのリンク
氏名 Miyabara, Y
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.HNnFOakh.html
出版者
出版者 ACADEMIC PRESS INC ELSEVIER SCIENCE
引用
内容記述タイプ Other
内容記述 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 360(2): 490-495 (2007)
書誌情報 en : BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

巻 360, 号 2, p. 490-495, 発行日 2007-08-24
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ ISSN
収録物識別子 0006-291X
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.bbrc.2007.06.086
関連名称
関連名称 10.1016/j.bbrc.2007.06.086
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000248159000033
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