{"_buckets": {"deposit": "b93e2b9e-f348-40cd-983b-a1def2dbc2d9"}, "_deposit": {"id": "12736", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "12736"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00012736", "sets": ["1221:1222"]}, "item_6_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2006-05", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "1092", "bibliographicPageStart": "1079", "bibliographicVolumeNumber": "44", "bibliographic_titles": [{"bibliographic_title": "Carbon"}]}]}, "item_6_description_30": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7\uff08\u30b3\u30f3\u30c6\u30f3\u30c4\u306e\u7a2e\u985e\uff09", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_31": {"attribute_name": "\u30d5\u30a9\u30fc\u30de\u30c3\u30c8\uff1amime\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "\u5f15\u7528", "attribute_value_mlt": [{"subitem_description": "Carbon. 44(6):1079-1092 (2006)", "subitem_description_type": "Other"}]}, "item_6_link_3": {"attribute_name": "\u4fe1\u5dde\u5927\u5b66\u7814\u7a76\u8005\u7dcf\u89a7\u3078\u306e\u30ea\u30f3\u30af", "attribute_value_mlt": [{"subitem_link_text": "Endo, M", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.uUTmZhkh.html"}, {"subitem_link_text": "Hayashi, T", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.jmLUbpkh.html"}]}, "item_6_link_67": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026KeyUT=000236683800008\u0026DestApp=WOS"}]}, "item_6_publisher_4": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Elsevier Science"}]}, "item_6_relation_46": {"attribute_name": "\u4ed6\u306e\u8cc7\u6e90\u3068\u306e\u95a2\u4fc2\uff1aURI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "http://www.elsevier.com/wps/find/journaldescription.cws_home/258/description"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://www.elsevier.com/wps/find/journaldescription.cws_home/258/description", "subitem_relation_type_select": "URI"}}]}, "item_6_relation_48": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1016/j.carbon.2005.08.006"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://dx.doi.org/10.1016/j.carbon.2005.08.006", "subitem_relation_type_select": "DOI"}}]}, "item_6_select_64": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_6_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0008-6223", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0008-6223", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_40": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00598943", "subitem_source_identifier_type": "NCID"}]}, "item_6_text_69": {"attribute_name": "wosonly authkey", "attribute_value_mlt": [{"subitem_text_value": "carbon nauotubes; chemical vapor deposition; optical microscopy; bioactivity"}]}, "item_6_text_70": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "STRUCTURAL-CHARACTERIZATION; PULMONARY TOXICITY; FIBERS; NANOFIBERS; EXPOSURE; SUBSETS; GROWTH"}]}, "item_6_textarea_68": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "We have evaluated the biological responses to four different types of carbon nanotubes (CNTs), by measuring CD4(+) and CD8(+) T-cells in peripheral blood, and by the histopathological study on tissues surrounding Subcutaneously implanted CNTs for up to 3 months. All mice survived, and no large changes in their weights were observed within our experimental period. After 1 week, only single-walled carbon nanotubes (SWNTs) activated major histocompatibility complex (MHC) class I pathway of antigen-antibody response system (higher CD4(+)/CD8(+) value), resulting in the appearance of an edematous aspect. After 2 weeks, significantly high values in CD4(+) and CD4(+)/CD8(+) without change in CD8(+) signified an activated MHC class II for all samples. It is worth noting that the toxicological response of CNTs was absolutely lower than that of asbestos. As a result, we envisaged that our result (relatively low toxicity of CNTs) will spur the mass-production, as well widespread application of CNTs in the near future. (c) 2005 Elsevier Ltd. All rights reserved."}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Koyama,  S"}], "nameIdentifiers": [{"nameIdentifier": "39182", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Endo,  M"}], "nameIdentifiers": [{"nameIdentifier": "39183", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kim,  YA"}], "nameIdentifiers": [{"nameIdentifier": "39184", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hayashi,  T"}], "nameIdentifiers": [{"nameIdentifier": "39185", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yanagisawa,  T"}], "nameIdentifiers": [{"nameIdentifier": "39186", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Osaka,  K"}], "nameIdentifiers": [{"nameIdentifier": "39187", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Koyama,  H"}], "nameIdentifiers": [{"nameIdentifier": "39188", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kuroiwa,  N"}], "nameIdentifiers": [{"nameIdentifier": "39189", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-28"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "No_8_Carbon_2006.pdf", "filesize": [{"value": "267.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 267700.0, "url": {"label": "No_8_Carbon_2006.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/12736/files/No_8_Carbon_2006.pdf"}, "version_id": "c6f06038-e19d-4c6c-897a-82eb5eef1738"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Role of systemic T-cells and histopathological aspects after subcutaneous implantation of various carbon nanotubes in mice", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Role of systemic T-cells and histopathological aspects after subcutaneous implantation of various carbon nanotubes in mice"}]}, "item_type_id": "6", "owner": "1", "path": ["1221/1222"], "permalink_uri": "http://hdl.handle.net/10091/98", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2007-02-19"}, "publish_date": "2007-02-19", "publish_status": "0", "recid": "12736", "relation": {}, "relation_version_is_last": true, "title": ["Role of systemic T-cells and histopathological aspects after subcutaneous implantation of various carbon nanotubes in mice"], "weko_shared_id": null}