{"_buckets": {"deposit": "21057a61-29c9-40b1-a284-03505eeb3a5b"}, "_deposit": {"id": "13527", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "13527"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00013527", "sets": ["1310"]}, "author_link": ["41358", "41359", "41360", "41361"], "item_1628147817048": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_6_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2008-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "2342", "bibliographicPageStart": "2335", "bibliographicVolumeNumber": "19", "bibliographic_titles": [{"bibliographic_title": "JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE"}]}]}, "item_6_description_19": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "The original publication is available at www.springerlink.com", "subitem_description_type": "Other"}]}, "item_6_description_30": {"attribute_name": "資源タイプ（コンテンツの種類）", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_31": {"attribute_name": "フォーマット：mimeタイプ", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE. 19(6): 2335-2342 (2008)", "subitem_description_type": "Other"}]}, "item_6_link_3": {"attribute_name": "信州大学研究者総覧へのリンク", "attribute_value_mlt": [{"subitem_link_text": "Fujii, T", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.WVyFjekV.html"}, {"subitem_link_text": "Ohkawa, K", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.gUfejekV.html"}, {"subitem_link_text": "Hirai, T", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.WFyCjekV.html"}]}, "item_6_link_67": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000254624600013"}]}, "item_6_publisher_4": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "SPRINGER"}]}, "item_6_relation_48": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1007/s10856-007-3341-x"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1007/s10856-007-3341-x", "subitem_relation_type_select": "DOI"}}]}, "item_6_select_64": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_6_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0957-4530", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0957-4530", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_40": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA10761712", "subitem_source_identifier_type": "NCID"}]}, "item_6_text_70": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "HISTAMINE-RELEASE; KERATINS; CULTIVATION; EXTRACTION; EXPRESSION; FOLLICLE; CATALOG; MEMBERS"}]}, "item_6_textarea_68": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "Human hair and nail are valuable materials for producing individual corresponding biocompatible materials. A rapid and convenient protein extraction method (Shindai method) and novel procedures for preparing their protein films from their extracts have been developed using human hair and nail. The effects of the human hair and nail proteins and their films on histamine release from rat peritoneal mast cells were investigated. Both protein solutions and their films, mainly consisting of keratins and matrix proteins, did not induce histamine release from the mast cells. Scanning electron microscopy (SEM) also showed that the mast cells were only slightly affected by adding the human hair and nail proteins or by incubating on their protein films. The IgE-dependent histamine release was inhibited by the hair and nail proteins and their films. Incubation of the mast cells with the hair and nail proteins prior to the addition of the IgE serum resulted in a high inhibition (50%) of the histamine release, while the inhibition was approximately 10% when the protein solutions were mixed with the mast cells after incubation with the IgE serum. These results suggest that the human hair and nail proteins and their films will be useful materials for antiallergic actions."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Fujii,  T"}], "nameIdentifiers": [{"nameIdentifier": "41358", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Murai,  S"}], "nameIdentifiers": [{"nameIdentifier": "41359", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ohkawa,  K"}], "nameIdentifiers": [{"nameIdentifier": "41360", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hirai,  T"}], "nameIdentifiers": [{"nameIdentifier": "41361", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-28"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Effects of human hair.pdf", "filesize": [{"value": "3.2 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 3200000.0, "url": {"label": "Effects of human hair.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/13527/files/Effects of human hair.pdf"}, "version_id": "078d8290-3b6c-43f9-8fb3-391a5abcea95"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Effects of human hair and nail proteins and their films on rat mast cells", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Effects of human hair and nail proteins and their films on rat mast cells", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["1310"], "permalink_uri": "http://hdl.handle.net/10091/1096", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2008-06-26"}, "publish_date": "2008-06-26", "publish_status": "0", "recid": "13527", "relation": {}, "relation_version_is_last": true, "title": ["Effects of human hair and nail proteins and their films on rat mast cells"], "weko_shared_id": -1}