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It is here well knoun that Phenoxybenzamine (PhB) \uff0ca-blocker\uff0cblocks the constriction effect of NE In this experiment\uff0cthe change of PhB effect on cold induced vasooscillation and on the level of central ear arterial temperature (T-CEA) was investigated under three different temperature conditions by using intact\uff0cunanesthetized rabbit ears. Tog et the direct drug effect\uff0cP hB was injected locally into the earlobe. 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