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METHODS The authors first confirmed that a common peroneal nerve injury caused more aggravating effects on lower limb motor function than tibial nerve injury, as assessed by the static sciatic index (SSI). Thereafter, rats were subjected to varying degrees of crush injury to the common peroneal nerve. At 48 hours after the injury, motor function was assessed using the SSI and slope-walking ability (with slope angles of 30 degrees and 45 degrees). The tibialis anterior muscle, a main muscle innervated by the common peroneal nerve, was removed. Muscle sections were co-labeled with neuronal class III beta-tubulin polyclopal antibody to identify the presence of axons and Alexa Fluor 488-conjugated alpha-bungarotoxin to identify the presence of motor endplates. RESULTS The evaluation of neuromuscular innervation showed a correlation between SSI scores and ratios of residual axons (r(s) = 0.68, p \u003c 0.01), and there was a statistically significant difference between slope-walking ability and ratios of residual axons (p \u003c 0.01). Moreover, the ratios of residual axons in the nerve-crushed rats with normal motor function (SSI above 20) ranged from 36.5% to 88.7%, and those ratios in the success group with slope-walking angles of 30 degrees and 45 degrees ranged from 14.7% to 88.7% and from 39.8% to 88.7%, respectively. CONCLUSIONS In this study of rodents, less than half of the motor axons were sufficient to maintain normal motor function of the lower limb."}]}, "item_1627890986942": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_be7fb7dd8ff6fe43", "subitem_version_type": "NA"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "唐澤, 未佳", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "103688", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-06-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "14MH015D_shinsa.pdf", "filesize": [{"value": "92.2 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 92200.0, "url": {"label": "内容の要旨", "url": "https://soar-ir.repo.nii.ac.jp/record/18954/files/14MH015D_shinsa.pdf"}, "version_id": "4d7ec6bf-ce2d-49c4-a42d-d06d79e19255"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-06-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 1, "filename": "14MH015D_yoshi.pdf", "filesize": [{"value": "126.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 126700.0, "url": {"label": "審査結果の要旨", "url": "https://soar-ir.repo.nii.ac.jp/record/18954/files/14MH015D_yoshi.pdf"}, "version_id": "67f977da-db74-43e4-b341-848caa9a9277"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-06-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 2, "filename": "14MH015D_ronbun.pdf", "filesize": [{"value": "532.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "© 2017 the American Association of Neurological Surgeons.", "licensetype": "license_note", "mimetype": "application/pdf", "size": 532300.0, "url": {"label": "博士論文の全文", "objectType": "fulltext", "url": "https://soar-ir.repo.nii.ac.jp/record/18954/files/14MH015D_ronbun.pdf"}, "version_id": "3e04b294-ac4c-4f69-b3b4-e73ab3a62f00"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "doctoral thesis", "resourceuri": "http://purl.org/coar/resource_type/c_db06"}]}, "item_title": "Effect of graded nerve pressure injuries on motor function(圧迫による神経損傷の程度と運動機能の関係)", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Effect of graded nerve pressure injuries on motor function(圧迫による神経損傷の程度と運動機能の関係)", "subitem_title_language": "en"}]}, "item_type_id": "14", "owner": "1", "path": ["849"], "permalink_uri": "http://hdl.handle.net/10091/00019716", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2017-06-06"}, "publish_date": "2017-06-06", "publish_status": "0", "recid": "18954", "relation": {}, "relation_version_is_last": true, "title": ["Effect of graded nerve pressure injuries on motor function(圧迫による神経損傷の程度と運動機能の関係)"], "weko_shared_id": -1}
Effect of graded nerve pressure injuries on motor function(圧迫による神経損傷の程度と運動機能の関係)
http://hdl.handle.net/10091/00019716
http://hdl.handle.net/10091/0001971661df6bd1-675f-4249-b2ed-931e5ee369ca
名前 / ファイル | ライセンス | アクション |
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2017-06-06 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Effect of graded nerve pressure injuries on motor function(圧迫による神経損傷の程度と運動機能の関係) | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_db06 | |||||
タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
唐澤, 未佳
× 唐澤, 未佳 |
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出版者 | ||||||
出版者 | 信州大学 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 唐澤 未佳. Effect of graded nerve pressure injuries on motor function(圧迫による神経損傷の程度と運動機能の関係). 信州大学, 2017, 博士論文. | |||||
書誌情報 |
発行日 2017-03-31 |
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学位授与番号 | ||||||
学位授与番号 | 13601甲第1057号 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2017-03-31 | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 13601 | |||||
学位授与機関名 | 信州大学(Shinshu university) | |||||
学位の区分 | ||||||
doctoral | ||||||
学位の分野 | ||||||
医学 | ||||||
学位の報告番号 | ||||||
甲第1057号 | ||||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 雑誌に発表。JOURNAL OF NEUROSURGERY. 122(6):1438-1443 (2015); doi:10.3171/2014.9.JNS141451. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Thesis | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | https://pubmed.ncbi.nlm.nih.gov/25748301/ | |||||
関連名称 | 25748301 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.3171/2014.9.JNS141451 | |||||
関連名称 | 10.3171/2014.9.JNS141451 | |||||
権利 | ||||||
権利情報 | © 2017 the American Association of Neurological Surgeons. | |||||
出版タイプ | ||||||
出版タイプ | NA | |||||
出版タイプResource | http://purl.org/coar/version/c_be7fb7dd8ff6fe43 | |||||
WoS | ||||||
Web of Science | ||||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000355031400027 |