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METHODS The authors first confirmed that a common peroneal nerve injury caused more aggravating effects on lower limb motor function than tibial nerve injury, as assessed by the static sciatic index (SSI). Thereafter, rats were subjected to varying degrees of crush injury to the common peroneal nerve. At 48 hours after the injury, motor function was assessed using the SSI and slope-walking ability (with slope angles of 30 degrees and 45 degrees). The tibialis anterior muscle, a main muscle innervated by the common peroneal nerve, was removed. Muscle sections were co-labeled with neuronal class III beta-tubulin polyclopal antibody to identify the presence of axons and Alexa Fluor 488-conjugated alpha-bungarotoxin to identify the presence of motor endplates. RESULTS The evaluation of neuromuscular innervation showed a correlation between SSI scores and ratios of residual axons (r(s) = 0.68, p \u003c 0.01), and there was a statistically significant difference between slope-walking ability and ratios of residual axons (p \u003c 0.01). Moreover, the ratios of residual axons in the nerve-crushed rats with normal motor function (SSI above 20) ranged from 36.5% to 88.7%, and those ratios in the success group with slope-walking angles of 30 degrees and 45 degrees ranged from 14.7% to 88.7% and from 39.8% to 88.7%, respectively. CONCLUSIONS In this study of rodents, less than half of the motor axons were sufficient to maintain normal motor function of the lower limb."}]}, "item_1627890986942": {"attribute_name": "\u51fa\u7248\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_be7fb7dd8ff6fe43", "subitem_version_type": "NA"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u5510\u6fa4, \u672a\u4f73"}], "nameIdentifiers": [{"nameIdentifier": "103688", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-06-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "14MH015D_shinsa.pdf", "filesize": [{"value": "92.2 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 92200.0, "url": {"label": "\u5185\u5bb9\u306e\u8981\u65e8", "url": "https://soar-ir.repo.nii.ac.jp/record/18954/files/14MH015D_shinsa.pdf"}, "version_id": "4d7ec6bf-ce2d-49c4-a42d-d06d79e19255"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-06-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 1, "filename": "14MH015D_yoshi.pdf", "filesize": [{"value": "126.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 126700.0, "url": {"label": "\u5be9\u67fb\u7d50\u679c\u306e\u8981\u65e8", "url": "https://soar-ir.repo.nii.ac.jp/record/18954/files/14MH015D_yoshi.pdf"}, "version_id": "67f977da-db74-43e4-b341-848caa9a9277"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-06-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 2, "filename": "14MH015D_ronbun.pdf", "filesize": [{"value": "532.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "\u00a9 2017 the American Association of Neurological Surgeons.", "licensetype": "license_note", "mimetype": "application/pdf", "size": 532300.0, "url": {"label": "\u535a\u58eb\u8ad6\u6587\u306e\u5168\u6587", "url": "https://soar-ir.repo.nii.ac.jp/record/18954/files/14MH015D_ronbun.pdf"}, "version_id": "3e04b294-ac4c-4f69-b3b4-e73ab3a62f00"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "doctoral thesis", "resourceuri": "http://purl.org/coar/resource_type/c_db06"}]}, "item_title": "Effect of graded nerve pressure injuries on motor function\uff08\u5727\u8feb\u306b\u3088\u308b\u795e\u7d4c\u640d\u50b7\u306e\u7a0b\u5ea6\u3068\u904b\u52d5\u6a5f\u80fd\u306e\u95a2\u4fc2\uff09", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Effect of graded nerve pressure injuries on motor function\uff08\u5727\u8feb\u306b\u3088\u308b\u795e\u7d4c\u640d\u50b7\u306e\u7a0b\u5ea6\u3068\u904b\u52d5\u6a5f\u80fd\u306e\u95a2\u4fc2\uff09", "subitem_title_language": "en"}]}, "item_type_id": "14", "owner": "1", "path": ["461/848/849"], "permalink_uri": "http://hdl.handle.net/10091/00019716", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2017-06-06"}, "publish_date": "2017-06-06", "publish_status": "0", "recid": "18954", "relation": {}, "relation_version_is_last": true, "title": ["Effect of graded nerve pressure injuries on motor function\uff08\u5727\u8feb\u306b\u3088\u308b\u795e\u7d4c\u640d\u50b7\u306e\u7a0b\u5ea6\u3068\u904b\u52d5\u6a5f\u80fd\u306e\u95a2\u4fc2\uff09"], "weko_shared_id": -1}
  1. 050 医学部, 大学院医学系研究科
  2. 0507 学位論文
  3. 博士(医学)

Effect of graded nerve pressure injuries on motor function(圧迫による神経損傷の程度と運動機能の関係)

http://hdl.handle.net/10091/00019716
61df6bd1-675f-4249-b2ed-931e5ee369ca
名前 / ファイル ライセンス アクション
14MH015D_shinsa.pdf 内容の要旨 (92.2 kB)
14MH015D_yoshi.pdf 審査結果の要旨 (126.7 kB)
14MH015D_ronbun.pdf 博士論文の全文 (532.3 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2017-06-06
タイトル
言語 en
タイトル Effect of graded nerve pressure injuries on motor function(圧迫による神経損傷の程度と運動機能の関係)
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_db06
タイプ doctoral thesis
著者 唐澤, 未佳

× 唐澤, 未佳

WEKO 103688

唐澤, 未佳

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出版者
出版者 信州大学
引用
内容記述タイプ Other
内容記述 唐澤 未佳. Effect of graded nerve pressure injuries on motor function(圧迫による神経損傷の程度と運動機能の関係). 信州大学, 2017, 博士論文.
書誌情報
発行日 2017-03-31
学位授与番号
学位授与番号 13601甲第1057号
学位授与年月日
学位授与年月日 2017-03-31
学位名
学位名 博士(医学)
学位授与機関
学位授与機関名
学位授与機関名 信州大学(Shinshu university)
学位の区分
Doctoral
学位の分野
医学
学位の報告番号
甲第1057号
内容記述
内容記述タイプ Other
内容記述 雑誌に発表。JOURNAL OF NEUROSURGERY. 122(6):1438-1443 (2015); doi:10.3171/2014.9.JNS141451.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Thesis
PubMed
関連識別子
識別子タイプ PMID
関連識別子 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=25748301
関連名称
関連名称 25748301
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.3171/2014.9.JNS141451
関連名称
関連名称 10.3171/2014.9.JNS141451
権利
権利情報 © 2017 the American Association of Neurological Surgeons.
出版タイプ
出版タイプ NA
出版タイプResource http://purl.org/coar/version/c_be7fb7dd8ff6fe43
WoS
Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000355031400027
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