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Importance of cystatin C and uric acid levels in the association of cardiometabolic risk factors in Japanese junior high school students(日本人中学生の心血管代謝危険因子との関連におけるシスタチンCおよび血清尿酸値の重要性). 信州大学, 2016, 博士論文.", "subitem_description_type": "Other"}]}, "item_14_dissertation_number_7": {"attribute_name": "学位授与番号", "attribute_value_mlt": [{"subitem_dissertationnumber": "13601甲第1076号"}]}, "item_14_link_74": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000394195800034"}]}, "item_14_publisher_4": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "信州大学"}]}, "item_14_relation_54": {"attribute_name": "PubMed", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "27138369"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://pubmed.ncbi.nlm.nih.gov/27138369/", "subitem_relation_type_select": "PMID"}}]}, "item_14_relation_55": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1016/j.jjcc.2016.03.013"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1016/j.jjcc.2016.03.013", "subitem_relation_type_select": "DOI"}}]}, "item_14_rights_69": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/"}]}, "item_14_select_71": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "ETD"}]}, "item_14_text_11": {"attribute_name": "学位の区分", "attribute_value_mlt": [{"subitem_text_value": "doctoral"}]}, "item_14_text_12": {"attribute_name": "学位の分野", "attribute_value_mlt": [{"subitem_text_value": "医学"}]}, "item_14_text_13": {"attribute_name": "学位の報告番号", "attribute_value_mlt": [{"subitem_text_value": "甲第1076号"}]}, "item_14_text_76": {"attribute_name": "wosonly authkey", "attribute_value_mlt": [{"subitem_text_value": "Serum uric acid; Cystatin C; Adolescent; Cardiovascular risk"}]}, "item_14_text_77": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "CHRONIC KIDNEY-DISEASE; CORONARY-HEART-DISEASE; METABOLIC SYNDROME; CARDIOVASCULAR-DISEASE; CHOLESTEROL RATIO; CAROTID ATHEROSCLEROSIS; HDL CHOLESTEROL; OBESE CHILDREN; YOUNG-ADULTS; EVENTS"}]}, "item_14_textarea_75": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "Background: Serum cystatin C (CysC), a novel marker of renal function, is associated with the components of metabolic syndrome in adults. Little is known about the utility of CysC and its association with cardiometabolic risks in young subjects. Methods and results: In a cohort of 454 Japanese junior high school students, the distribution of serum CysC levels and associated variables were analyzed. CysC levels were significantly higher in boys than in girls (0.92 +/- 0.10 mg/L vs. 0.77 +/- 0.08 mg/L, p \u003c 0.001). CysC was significantly correlated with serum creatinine (r = 0.473, p \u003c 0.001), and serum uric acid (SUA) (r = 0.546, p \u003c 0.001). Multivariable regression analysis revealed significant associations between CysC and SUA in all subjects (beta = 0.241, p \u003c 0.001), and in boys and girls separately (beta = 0.264 and 0.240, respectively, both p \u003c 0.001). Importantly, subjects with elevation of both serum CysC and SUA levels had the highest ratio of triglyceride to high-density lipoprotein cholesterol. Conclusions: CysC had significant associations with both creatinine and SUA in Japanese junior high school students. The concomitant elevation of serum CysC and SUA levels was associated with subclinical lipid metabolism dysregulation, and suggested the presence of cardiometabolic risk accumulation. (C) 2016 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved."}]}, "item_1627890986942": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_be7fb7dd8ff6fe43", "subitem_version_type": "NA"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "原田, 美貴子", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "103710", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-06-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "12MH021A_shinsa.pdf", "filesize": [{"value": "128.6 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 128600.0, "url": {"label": "内容の要旨", "url": "https://soar-ir.repo.nii.ac.jp/record/18976/files/12MH021A_shinsa.pdf"}, "version_id": "a7c62c60-f9be-4531-8140-1f27fd28b8cb"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-06-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 1, "filename": "12MH021A_yoshi.pdf", "filesize": [{"value": "162.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 162900.0, "url": {"label": "審査結果の要旨", "url": "https://soar-ir.repo.nii.ac.jp/record/18976/files/12MH021A_yoshi.pdf"}, "version_id": "dfa82bea-a904-438e-a907-cc95193ac319"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-01-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 2, "filename": "12MH021A_ronbun.pdf", "filesize": [{"value": "213.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "© 2017. 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Importance of cystatin C and uric acid levels in the association of cardiometabolic risk factors in Japanese junior high school students(日本人中学生の心血管代謝危険因子との関連におけるシスタチンCおよび血清尿酸値の重要性)
http://hdl.handle.net/10091/00019738
http://hdl.handle.net/10091/00019738845b5c9c-2281-4e2f-a9a3-3c603537e4aa
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審査結果の要旨 (162.9 kB)
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博士論文の全文 (213.9 kB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2017-06-06 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Importance of cystatin C and uric acid levels in the association of cardiometabolic risk factors in Japanese junior high school students(日本人中学生の心血管代謝危険因子との関連におけるシスタチンCおよび血清尿酸値の重要性) | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_db06 | |||||
タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
原田, 美貴子
× 原田, 美貴子 |
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出版者 | ||||||
出版者 | 信州大学 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 原田 美貴子. Importance of cystatin C and uric acid levels in the association of cardiometabolic risk factors in Japanese junior high school students(日本人中学生の心血管代謝危険因子との関連におけるシスタチンCおよび血清尿酸値の重要性). 信州大学, 2016, 博士論文. | |||||
書誌情報 |
発行日 2016-03-31 |
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学位授与番号 | ||||||
学位授与番号 | 13601甲第1076号 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2016-03-31 | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 13601 | |||||
学位授与機関名 | 信州大学(Shinshu university) | |||||
学位の区分 | ||||||
doctoral | ||||||
学位の分野 | ||||||
医学 | ||||||
学位の報告番号 | ||||||
甲第1076号 | ||||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 雑誌に発表。JOURNAL OF CARDIOLOGY. 69(1):222-227 (2017); doi:10.1016/j.jjcc.2016.03.013. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Thesis | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | https://pubmed.ncbi.nlm.nih.gov/27138369/ | |||||
関連名称 | 27138369 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.jjcc.2016.03.013 | |||||
関連名称 | 10.1016/j.jjcc.2016.03.013 | |||||
権利 | ||||||
権利情報 | © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
出版タイプ | ||||||
出版タイプ | NA | |||||
出版タイプResource | http://purl.org/coar/version/c_be7fb7dd8ff6fe43 | |||||
WoS | ||||||
Web of Science | ||||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000394195800034 |