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  1. 050 医学部, 大学院医学系研究科 (Faculty&Graduate School of Medicine)
  2. 0501 学術論文 (Journal Articles)

Association analysis of toll-like receptor 4 polymorphisms in Japanese primary biliary cirrhosis

http://hdl.handle.net/10091/00019820
362f969e-5314-4ca9-96f5-9505e751270a
プレビュー
名前 / ファイル ライセンス Actions
Association_analysis_toll-like_receptor_4_polymorphisms.pdf Association_analysis_toll-like_receptor_4_polymorphisms.pdf (228.2 kB)
© 2013. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
item type 学術雑誌論文 / Journal Article(1)
公開日 2017-09-20
タイトル
タイトル Association analysis of toll-like receptor 4 polymorphisms in Japanese primary biliary cirrhosis
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Morita, Susumu

× Morita, Susumu

WEKO 103932

Morita, Susumu

Search repository
Joshita, Satoru

× Joshita, Satoru

WEKO 103933

Joshita, Satoru

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Umemura, Takeji

× Umemura, Takeji

WEKO 103934

Umemura, Takeji

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Katsuyama, Yoshihiko

× Katsuyama, Yoshihiko

WEKO 103935

Katsuyama, Yoshihiko

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Kimura, Takefumi

× Kimura, Takefumi

WEKO 103936

Kimura, Takefumi

Search repository
Komatsu, Michiharu

× Komatsu, Michiharu

WEKO 103937

Komatsu, Michiharu

Search repository
Matsumoto, Akihiro

× Matsumoto, Akihiro

WEKO 103938

Matsumoto, Akihiro

Search repository
Yoshizawa, Kaname

× Yoshizawa, Kaname

WEKO 103939

Yoshizawa, Kaname

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Kamijo, Atsushi

× Kamijo, Atsushi

WEKO 103940

Kamijo, Atsushi

Search repository
Yamamura, Nobuyoshi

× Yamamura, Nobuyoshi

WEKO 103941

Yamamura, Nobuyoshi

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Tanaka, Eiji

× Tanaka, Eiji

WEKO 103942

Tanaka, Eiji

Search repository
Ota, Masao

× Ota, Masao

WEKO 103943

Ota, Masao

Search repository
信州大学研究者総覧へのリンク
Joshita, Satoru
http://soar-rd.shinshu-u.ac.jp/profile/ja.PeLNbVym.html
信州大学研究者総覧へのリンク
Umemura, Takeji
http://soar-rd.shinshu-u.ac.jp/profile/ja.ymSpgpkh.html
信州大学研究者総覧へのリンク
Kimura, Takefumi
http://soar-rd.shinshu-u.ac.jp/profile/ja.uNymWUkh.html
信州大学研究者総覧へのリンク
Matsumoto, Akihiro
http://soar-rd.shinshu-u.ac.jp/profile/ja.jhSCPUym.html
信州大学研究者総覧へのリンク
Tanaka, Eiji
http://soar-rd.shinshu-u.ac.jp/profile/ja.HFDCHekh.html
信州大学研究者総覧へのリンク
Ota, Masao
http://soar-rd.shinshu-u.ac.jp/profile/ja.ZefVOFkh.html
出版者
出版者 ELSEVIER SCIENCE INC
引用
内容記述タイプ Other
内容記述 HUMAN IMMUNOLOGY. 74(2):219-222 (2013)
書誌情報 HUMAN IMMUNOLOGY

巻 74, 号 2, p. 219-222, 発行日 2013-02
抄録
内容記述タイプ Abstract
内容記述 Primary biliary cirrhosis (PBC) is characterized by portal inflammation and immune-mediated destruction of intrahepatic bile ducts that often result in liver failure. Toll-like receptor (TLR) 4 recognizes lipopolysaccharides of Gram-negative bacteria. Infectious agents have been suspected to play a crucial role in PBC pathogenesis since TLR4 expression was found in bile duct epithelial cells and periportal hepatocytes in liver tissues of PBC. To assess the potential contribution of TLR4 SNPs to the development of this disease, we genotyped five SNPs in TLR4 in 261 PBC patients and 359 controls using a TaqMan assay. No significant positive associations with either PBC susceptibility or progression were uncovered. These results indicate that TLR4 polymorphisms do not play a prominent role in the development of PBC in Japanese patients. (C) 2012 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ ISSN
収録物識別子 0198-8859
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00214087
PubMed
関連識別子
識別子タイプ PMID
関連識別子 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=23142582
関連名称
関連名称 23142582
DOI
関連識別子
識別子タイプ DOI
関連識別子 http://doi.org/10.1016/j.humimm.2012.10.022
関連名称
関連名称 10.1016/j.humimm.2012.10.022
権利
権利情報 © 2013. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
著者版フラグ
値 author
WoS
Web of Science
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000317874000014
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