| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-12-25 |
| タイトル |
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タイトル |
Quantitative Evaluation of Liver Function with Use of Gadoxetate Disodium-enhanced MR Imaging |
| 言語 |
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言語 |
eng |
| DOI |
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関連識別子 |
https://doi.org/10.1148/radiol.11100586 |
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関連名称 |
10.1148/radiol.11100586 |
| 資源タイプ |
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資源 |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 著者 |
Yamada, Akira
Hara, Takeshi
Li, Feng
Fujinaga, Yasunari
Ueda, Kazuhiko
Kadoya, Masumi
Doi, Kunio
|
| 信州大学研究者総覧へのリンク |
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氏名 |
Yamada, Akira |
|
URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.jVnVgUkh.html |
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Fujinaga, Yasunari |
|
URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.WFyeHVkh.html |
| 出版者 |
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出版者 |
RADIOLOGICAL SOC NORTH AMERICA |
| 引用 |
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内容記述 |
RADIOLOGY. 260(3):727-733 (2011) |
| 書誌情報 |
RADIOLOGY
巻 260,
号 3,
p. 727-733,
発行日 2011-09
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| 抄録 |
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内容記述 |
Purpose: To determine whether liver function correlating with indocyanine green (ICG) clearance could be estimated quantitatively from gadoxetate disodium-enhanced magnetic resonance (MR) images. Materials and Methods: This retrospective study was approved by the institutional review board, and the requirement for informed consent was waived. Twenty-three consecutive patients who underwent an ICG clearance test and gadoxetate disodium-enhanced MR imaging with the same parameters as were used for a preoperative examination were chosen. The hepatocellular uptake index (HUI) from liver volume (V(L)) and mean signal intensity of the liver on contrastenhanced T1-weighted images with fat suppression (L(20)) and mean signal intensity of the spleen on contrastenhanced T1-weighted images with fat suppression (S(20)) on 3D gradient-echo T1-weighted images with fat suppression obtained at 20 minutes after gadoxetate disodium (0.025 mmol per kilogram of body weight) administration was determined with the following equation: V(L)[(L(20)/S(20)) 2 1]. The correlation of the plasma disappearance rate of ICG (ICG-PDR) and various factors derived from MR imaging, including HUI, iron and fat deposition in the liver and spleen, and spleen volume (V(S)), were evaluated with stepwise multiple regression analysis. The difference between the ratio of the remnant HUI to the HUI of the total liver (rHUI/HUI) and ratio of the liver remnant V(L) to the total V(L)(rV(L)/V(L)) was evaluated in four patients who had segmental heterogeneity of liver function. Results: HUI and V(S) were the factors significantly correlated with ICG-PDR (R = 0.87). The mean value and its 95% confidence interval were 0.18 and 0.01 to 0.34, respectively, for the following calculation: (rHUI/HUI) 2 (rV(L)/V(L)). Conclusion: The liver function correlating with ICG-PDR can be estimated quantitatively from the signal intensities and the volumes of the liver and spleen on gadoxetate disodium-enhanced MR images, which may improve the estimation of segmental liver function. (C) RSNA, 2011 |
| 資源タイプ（コンテンツの種類） |
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| ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0033-8419 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00800818 |
| PubMed |
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|
識別子タイプ |
PMID |
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関連識別子 |
https://pubmed.ncbi.nlm.nih.gov/21712472 |
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関連名称 |
21712472 |
| 権利 |
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|
権利情報 |
© RSNA, 2011 |
| 出版タイプ |
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出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| WoS |
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|
URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000293944700014 |
Quantitative_evaluation_of_liver_function_by_use_of_gadoxetate_disodium.pdf (520.9 kB)
