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Presepsin as a predictor of positive blood culture among newborns suspected sepsis(プレセプシンによる新生児敗血症疑診例における血培陽性症例の予測). 信州大学, 2018, 博士論文.", "subitem_description_type": "Other"}]}, "item_14_dissertation_number_7": {"attribute_name": "学位授与番号", "attribute_value_mlt": [{"subitem_dissertationnumber": "13601乙第1215号"}]}, "item_14_link_74": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000426076600010"}]}, "item_14_publisher_4": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "信州大学"}]}, "item_14_relation_54": {"attribute_name": "PubMed", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "29205640"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://pubmed.ncbi.nlm.nih.gov/29205640/", "subitem_relation_type_select": "PMID"}}]}, "item_14_relation_55": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1111/ped.13469"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1111/ped.13469", "subitem_relation_type_select": "DOI"}}]}, "item_14_rights_69": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2017 Japan Pediatric Society / This is the accepted version of the following article: Miyosawa, Y. , Akazawa, Y. , Kamiya, M. , Nakamura, C. , Takeuchi, Y. , Kusakari, M. and Nakamura, T. (2018), Presepsin as a predictor of positive blood culture in suspected neonatal sepsis. Pediatrics International, 60: 157-161. doi:10.1111/ped.13469, which has been published in final form at https://doi.org/10.1111/ped.13469 ."}]}, "item_14_select_71": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "ETD"}]}, "item_14_text_11": {"attribute_name": "学位の区分", "attribute_value_mlt": [{"subitem_text_value": "doctoral"}]}, "item_14_text_12": {"attribute_name": "学位の分野", "attribute_value_mlt": [{"subitem_text_value": "医学"}]}, "item_14_text_13": {"attribute_name": "学位の報告番号", "attribute_value_mlt": [{"subitem_text_value": "乙第1215号"}]}, "item_14_text_76": {"attribute_name": "wosonly authkey", "attribute_value_mlt": [{"subitem_text_value": "newborn; presepsin; sepsis"}]}, "item_14_text_77": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "C-REACTIVE PROTEIN; EARLY-ONSET SEPSIS; PRETERM NEWBORNS; PROCALCITONIN CONCENTRATIONS; DIAGNOSIS; CD14; RELIABILITY; INFECTION; INSIGHTS; RISK"}]}, "item_14_textarea_75": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "BackgroundAlthough the incidence of neonatal sepsis is decreasing, neonatal sepsis remains a severe life-threatening disease. No current biochemical marker can provide perfect diagnostic accuracy for neonatal sepsis. The aim of this study was therefore to evaluate the accuracy of presepsin (P-SEP) as a novel biomarker of bacterial infection for neonatal sepsis diagnosis. MethodsWe prospectively studied newborns with sepsis (sepsis group; n = 13) during the first 30days after birth and compared them with control preterm newborns (control group; n = 18). In addition, we evaluated term newborns with some clinical signs of early onset sepsis (non-sepsis term group; n = 35). ResultsP-SEP in the sepsis group was significantly higher than in the control group (P \u003c 0.001) The area under the curve for P-SEP was 0.868 (95%CI: 0.71-1.00). A P-SEP cut-off of 795pg/mL was established, with 85% sensitivity and 89% specificity. The positive and negative predictive values were 85% and 89%, respectively. In the non-sepsis term group, P-SEP had better stability than white blood cells and C-reactive protein for 3days after birth. ConclusionsP-SEP can better discriminate between infections and non-infectious inflammatory conditions than the currently used biomarkers."}]}, "item_1627890986942": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_be7fb7dd8ff6fe43", "subitem_version_type": "NA"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "三代澤, 幸秀", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "105939", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-06-28"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "17MR0009_yoshi.pdf", "filesize": [{"value": "129.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 129800.00000000001, "url": {"label": "内容の要旨", "url": "https://soar-ir.repo.nii.ac.jp/record/19986/files/17MR0009_yoshi.pdf"}, "version_id": "a9598a00-aebc-4fb2-9701-4fced5902238"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-06-28"}], "displaytype": "detail", "download_preview_message": "", "file_order": 1, "filename": "17MR0009_shinsa.pdf", "filesize": [{"value": "83.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 83700.0, "url": {"label": "審査結果の要旨", "url": "https://soar-ir.repo.nii.ac.jp/record/19986/files/17MR0009_shinsa.pdf"}, "version_id": "b0f7d296-3a51-4920-8a82-5d26f7d31037"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-02-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 2, "filename": "17MR0009_ronbun.pdf", "filesize": [{"value": "259.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "© 2017 Japan Pediatric Society / This is the accepted version of the following article: Miyosawa, Y. , Akazawa, Y. , Kamiya, M. , Nakamura, C. , Takeuchi, Y. , Kusakari, M. and Nakamura, T. 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Presepsin as a predictor of positive blood culture among newborns suspected sepsis(プレセプシンによる新生児敗血症疑診例における血培陽性症例の予測)
http://hdl.handle.net/10091/00020747
http://hdl.handle.net/10091/000207470b160505-3cc7-43b8-b5fb-170b132e0b2b
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内容の要旨 (129.8 kB)
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審査結果の要旨 (83.7 kB)
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博士論文の全文 (259.9 kB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2018-06-28 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Presepsin as a predictor of positive blood culture among newborns suspected sepsis(プレセプシンによる新生児敗血症疑診例における血培陽性症例の予測) | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_db06 | |||||
タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
三代澤, 幸秀
× 三代澤, 幸秀 |
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出版者 | ||||||
出版者 | 信州大学 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 三代澤 幸秀. Presepsin as a predictor of positive blood culture among newborns suspected sepsis(プレセプシンによる新生児敗血症疑診例における血培陽性症例の予測). 信州大学, 2018, 博士論文. | |||||
書誌情報 |
発行日 2018-02-28 |
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学位授与番号 | ||||||
学位授与番号 | 13601乙第1215号 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2018-02-28 | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 13601 | |||||
学位授与機関名 | 信州大学(Shinshu university) | |||||
学位の区分 | ||||||
doctoral | ||||||
学位の分野 | ||||||
医学 | ||||||
学位の報告番号 | ||||||
乙第1215号 | ||||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 雑誌に発表。PEDIATRICS INTERNATIONAL. 60(2):157-161 (2018); doi:10.1111/ped.13469. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Thesis | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | https://pubmed.ncbi.nlm.nih.gov/29205640/ | |||||
関連名称 | 29205640 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1111/ped.13469 | |||||
関連名称 | 10.1111/ped.13469 | |||||
権利 | ||||||
権利情報 | © 2017 Japan Pediatric Society / This is the accepted version of the following article: Miyosawa, Y. , Akazawa, Y. , Kamiya, M. , Nakamura, C. , Takeuchi, Y. , Kusakari, M. and Nakamura, T. (2018), Presepsin as a predictor of positive blood culture in suspected neonatal sepsis. Pediatrics International, 60: 157-161. doi:10.1111/ped.13469, which has been published in final form at https://doi.org/10.1111/ped.13469 . | |||||
出版タイプ | ||||||
出版タイプ | NA | |||||
出版タイプResource | http://purl.org/coar/version/c_be7fb7dd8ff6fe43 | |||||
WoS | ||||||
Web of Science | ||||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000426076600010 |