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Myogenetic oligodeoxynucleotide complexed with berberine promotes differentiation of chicken myoblasts
http://hdl.handle.net/10091/0002000344
http://hdl.handle.net/10091/0002000344b6f7be5f-371e-4ebb-824e-6653f45e778b
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||
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公開日 | 2021-07-27 | |||||||||||||||||||
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タイトル | Myogenetic oligodeoxynucleotide complexed with berberine promotes differentiation of chicken myoblasts | |||||||||||||||||||
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言語 | eng | |||||||||||||||||||
DOI | ||||||||||||||||||||
関連タイプ | isVersionOf | |||||||||||||||||||
関連識別子 | 10.1111/asj.13597 | |||||||||||||||||||
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資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||
タイプ | journal article | |||||||||||||||||||
著者 |
Nihashi, Yuma
× Nihashi, Yuma
× Shinji, Sayaka
× Umezawa, Koji
× Shimosato, Takeshi
× Ono, Tamao
× Kagami, Hiroshi
× Takaya, Tomohide
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信州大学研究者総覧へのリンク | ||||||||||||||||||||
氏名 | 梅澤, 公二 | |||||||||||||||||||
URL | https://soar-rd.shinshu-u.ac.jp/profile/ja.yVcFPhkh.html | |||||||||||||||||||
信州大学研究者総覧へのリンク | ||||||||||||||||||||
氏名 | 下里, 剛士 | |||||||||||||||||||
URL | https://soar-rd.shinshu-u.ac.jp/profile/ja.ONLCjFkV.html | |||||||||||||||||||
信州大学研究者総覧へのリンク | ||||||||||||||||||||
氏名 | 小野, 珠乙 | |||||||||||||||||||
URL | https://soar-rd.shinshu-u.ac.jp/profile/ja.WFfCPpkh.html | |||||||||||||||||||
信州大学研究者総覧へのリンク | ||||||||||||||||||||
氏名 | 鏡味, 裕 | |||||||||||||||||||
URL | https://soar-rd.shinshu-u.ac.jp/profile/ja.OeyUPUkh.html | |||||||||||||||||||
信州大学研究者総覧へのリンク | ||||||||||||||||||||
氏名 | 高谷, 智英 | |||||||||||||||||||
URL | https://soar-rd.shinshu-u.ac.jp/profile/ja.yUcePUkh.html | |||||||||||||||||||
出版者 | ||||||||||||||||||||
出版者 | 公益社団法人日本畜産学会 | |||||||||||||||||||
出版者 | ||||||||||||||||||||
出版者 | Wiley | |||||||||||||||||||
引用 | ||||||||||||||||||||
内容記述 | Animal Science Journal. 92(1) : e13597 (2021) | |||||||||||||||||||
書誌情報 |
ja : Animal Science Journal 巻 92, 号 1, p. e13597-e13597, 発行日 2021-07-26 |
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抄録 | ||||||||||||||||||||
内容記述 | Myoblasts are myogenic precursors that develop into myotubes during muscle formation. Improving efficiency of myoblast differentiation is important for advancing meat production by domestic animals. We recently identified novel oligodeoxynucleotides (ODNs) termed myogenetic ODNs (myoDNs) that promote the differentiation of mammalian myoblasts. An isoquinoline alkaloid, berberine, forms a complex with one of the myoDNs, iSN04, and enhances its activities. This study investigated the effects of myoDNs on chicken myoblasts to elucidate their species-specific actions. Seven myoDNs (iSN01-iSN07) were found to facilitate the differentiation of chicken myoblasts into myosin heavy chain (MHC)-positive myotubes. The iSN04-berberine complex exhibited a higher myogenetic activity than iSN04 alone, which was shown to enhance the differentiation of myoblasts into myotubes and the upregulated of myogenic gene expression (MyoD, myogenin, MHC, and myomaker). These data indicate that myoDNs promoting chicken myoblast differentiation may be used as potential feed additives in broiler diets. | |||||||||||||||||||
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収録物識別子タイプ | EISSN | |||||||||||||||||||
収録物識別子 | 1344-3941 | |||||||||||||||||||
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収録物識別子タイプ | NCID | |||||||||||||||||||
収録物識別子 | AA11677214 | |||||||||||||||||||
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出版タイプ | AM | |||||||||||||||||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |
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Nihashi, Yuma, Shinji, Sayaka, Umezawa, Koji, Shimosato, Takeshi, Ono, Tamao, Kagami, Hiroshi, Takaya, Tomohide, 2021, Myogenetic oligodeoxynucleotide complexed with berberine promotes differentiation of chicken myoblasts: Wiley, e13597–e13597 p.
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