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His chest CT showed only mild radiation pneumonitis in the apex of his lung. After the initial treatment using antibiotics he showed diffuse ground glass opacity on his chest CT. He was finally diagnosed with pneumocystis pneumonia (PCP) by bronchoalveolar lavage. After oral administration of sulfamethoxazole-trimethoprim his clinical symptoms were immediately cured. Cetuximab is a recombinant human/mouse chimeric epidermal growth factor receptor (EGFR) monoclonal antibody, which was approved for head and neck cancer in Japan in 2012. Pneumocystis pneumonia during BRT with cetuximab for head and neck cancer is extremely rare. We investigated 7 patients, including the present patient, treated by BRT with cetuximab in our hospital and found that all of the patients\u2019 lymphocytes during BRT were under 500/\u03bcl, which could be a risk factor for PCP. It should be recognized that the depletion of lymphocytes in BRT can result in PCP. 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