Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2022-11-14 |
タイトル |
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タイトル |
Detection of Acinetobacter pittii ST220 co-producing NDM-1 and OXA-820 carbapenemases from a hospital sink in a non-endemic country of NDM |
言語 |
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言語 |
eng |
DOI |
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関連タイプ |
isIdenticalTo |
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関連識別子 |
https://doi.org/10.1016/j.jgar.2019.11.013 |
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関連名称 |
10.1016/j.jgar.2019.11.013 |
キーワード |
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主題 |
Acinetobacter pittii, bla(NDM-1), bla(OXA-820), Hospital sink, ST220, Biofilm-associated genes |
資源タイプ |
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資源 |
http://purl.org/coar/resource_type/c_6501 |
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タイプ |
journal article |
著者 |
Iimura, Masaki
Hayashi, Wataru
Arai, Eriko
Natori, Tatsuya
Horiuchi, Kazuki
Matsumoto, Go
Tanaka, Hayato
Soga, Eiji
Nagano, Yukiko
Nagano, Noriyuki
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信州大学研究者総覧へのリンク |
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氏名 |
松本, 剛 |
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URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.ZNnePUym.html |
信州大学研究者総覧へのリンク |
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氏名 |
長野, 由紀子 |
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URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.OUAeumyC.html |
信州大学研究者総覧へのリンク |
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氏名 |
長野, 則之 |
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URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.HULFumkh.html |
出版者 |
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出版者 |
Elsevier |
引用 |
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内容記述 |
Journal of Global Antimicrobial Resistance 21 : 353-356(2020) |
書誌情報 |
Journal of Global Antimicrobial Resistance
巻 21,
p. 353-356,
発行日 2020-06
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抄録 |
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内容記述 |
Objectives: NDM-1 is by far one of the most commonly prevalent carbapenemases in Enterobacteriaceae and Acinetobacter baumannii. This study presented an Acinetobacter pittii (A. pittii) isolate co-harboring blaNDM-1 and blaOXA-820 from a university hospital sink, where New Delhi metallo-β-lactamase (NDM) producers have not been found in either patients or their environments.<br> Methods: Whole-genome sequencing was performed on the HiSeq 4000 platform, and the reads were de novo assembled using the A5-miSeq Assembly pipeline. Annotation of the resulting scaffolds were performed by using the DDBJ Fast Annotation and Submission Tool (DFAST). The blaNDM-1-carrying plasmid was determined. Results:<br> The A. pittii ST220 strain SU1805 detected from a sink strainer in the treatment room was resistant to imipenem and meropenem. Antimicrobial resistance genes blaNDM-1, blaOXA-820, blaADC-43, and aphA6 were found in this strain. The blaNDM-1 was found to be located downstream of an ISAba125 element on a plasmid pSU1805NDM with a size of 41,022 bp, and GC content of 38.3% harbouring 48 protein-coding genes. The aphA6 gene was also located upstream of the ISAba125 on the same plasmid. The A. pittii intrinsic blaOXA-213-like gene blaOXA-820 was located between fxsA and yncA genes in the chromosome. The strain also harboured biofilm-associated genes such as ompA, the csu operon and their regulating genes bfmRS. Conclusion:<br> This study described the first isolation of NDM-1-producing A. pittii in Japan, and highlighted the importance of proper implementation of measures against AMR for sink drainage systems, since NDM producers may have already been hidden in such environments in a non-endemic country of NDM. |
資源タイプ(コンテンツの種類) |
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内容記述 |
Article |
ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
2213-7165 |
PubMed |
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関連識別子 |
https://pubmed.ncbi.nlm.nih.gov/31783194/ |
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関連名称 |
31783194 |
権利 |
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権利情報 |
© 2020 The Authors. Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy. This is an open access article under the CC BY-NC-ND license (http://creativecommons. org/licenses/by-nc-nd/4.0/). |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |