Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2018-09-18 |
タイトル |
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タイトル |
Highly purified, multi-wall carbon nanotubes induce light-chain 3B expression in human lung cells |
言語 |
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言語 |
eng |
DOI |
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関連識別子 |
https://doi.org/10.1016/j.bbrc.2013.09.089 |
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関連名称 |
10.1016/j.bbrc.2013.09.089 |
キーワード |
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主題 |
Bronchial epithelial cells, Carbon nanotube, Autophagy, LC3B |
資源タイプ |
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資源 |
http://purl.org/coar/resource_type/c_6501 |
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タイプ |
journal article |
著者 |
Tsukahara, Tamotsu
Matsuda, Yoshikazu
Usui, Yuki
Haniu, Hisao
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信州大学研究者総覧へのリンク |
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氏名 |
Haniu, Hisao |
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URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.jakpPmSa.html |
出版者 |
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出版者 |
ACADEMIC PRESS INC ELSEVIER SCIENCE |
引用 |
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内容記述 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.440(2):348-353(2013) |
書誌情報 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
巻 440,
号 2,
p. 348-353,
発行日 2013-10-18
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抄録 |
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内容記述 |
Bronchial epithelial cells are targets of inhalation and play a critical role in the maintenance of mucosal integrity as mechanical barriers against various particles. Our previous result suggest that vapor-grown carbon fiber, HTT2800, which is one of the most highly purified multi-wall carbon nanotubes (MWCNT) showed cellular uptake of the carbon nanotube, increased cell death, enhanced DNA damage, and induced cytokine release. Increasing evidence suggests that autophagy may critically influence vital cellular processes such as apoptosis, cell proliferation and inflammation and thereby may play a critical role in pulmonary diseases. Autophagy was recently recognized as a critical cell death pathway, and autophagosome accumulation has been found to be associated with the exposure of various nanoparticles. In this study, the authors focus on the autophagic responses of HTT2800 exposure. The HTT2800-exposed cells induced LC3B expression and induced cell growth inhibition. |
資源タイプ(コンテンツの種類) |
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内容記述 |
Article |
ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0006-291X |
書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA00564395 |
PubMed |
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関連識別子 |
https://www.ncbi.nlm.nih.gov/pubmed/24076389 |
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関連名称 |
24076389 |
出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
WoS |
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URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000326137700026 |