ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "5b9181b8-de94-4a41-ad06-c918f40c7963"}, "_deposit": {"id": "20217", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "20217"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00020217", "sets": ["462"]}, "author_link": ["106573", "106574", "106575", "106576", "106577", "106578", "106579", "106580", "106581", "106582", "106583", "106584", "106585"], "item_1628147817048": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_6_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2017-02-24", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageStart": "e0172601", "bibliographicVolumeNumber": "12", "bibliographic_titles": [{"bibliographic_title": "PLOS ONE"}]}]}, "item_6_description_20": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Many recent studies have been conducted to assess the ability of composite materials containing carbon nanotubes (CNTs) with high bone affinity to serve as scaffolds in bone regenerative medicine. These studies have demonstrated that CNTs can effectively induce bone formation. However, no studies have investigated the usefulness of scaffolds consisting exclusively of CNTs in bone regenerative medicine. We built a three-dimensional block entity with maximized mechanical strength from multi-walled CNTs (MWCNT blocks) and evaluated their efficacy as scaffold material for bone repair. When MWCNT blocks containing recombinant human bone morphogenetic protein-2 (rhBMP-2) were implanted in mouse muscle, ectopic bone was formed in direct contact with the blocks. Their bone marrow densities were comparable to those of PET-reinforced collagen sheets with rhBMP-2. On day 1 and day 3, MC3T3-E1 preosteoblasts were attached to the scaffold surface of MWCNT blocks than that of PET-reinforced collagen sheets. They also showed a maximum compression strength comparable to that of cortical bone. Our MWCNT blocks are expected to serve as bone defect filler and scaffold material for bone regeneration.", "subitem_description_type": "Abstract"}]}, "item_6_description_30": {"attribute_name": "資源タイプ(コンテンツの種類)", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "PLOS ONE.12(2):e0172601(2017)", "subitem_description_type": "Other"}]}, "item_6_link_3": {"attribute_name": "信州大学研究者総覧へのリンク", "attribute_value_mlt": [{"subitem_link_text": "Haniu, Hisao", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.jakpPmSa.html"}, {"subitem_link_text": "Okamoto, Masanori", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.uafabVym.html"}, {"subitem_link_text": "Aoki, Kaoru", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.WeDpbhym.html"}, {"subitem_link_text": "Kato, Hiroyuki", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.WVkCbaSp.html"}, {"subitem_link_text": "Saito, Naoto", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.WpkhuUkh.html"}]}, "item_6_link_67": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000394688200098"}]}, "item_6_publisher_4": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "PUBLIC LIBRARY SCIENCE"}]}, "item_6_relation_47": {"attribute_name": "PubMed", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "28235026"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://www.ncbi.nlm.nih.gov/pubmed/28235026", "subitem_relation_type_select": "PMID"}}]}, "item_6_relation_48": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1371/journal.pone.0172601"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1371/journal.pone.0172601", "subitem_relation_type_select": "DOI"}}]}, "item_6_rights_62": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2017 Tanaka et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited"}]}, "item_6_select_64": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_6_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1932-6203", "subitem_source_identifier_type": "PISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1932-6203", "subitem_source_identifier_type": "PISSN"}]}, "item_6_text_70": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "OSTEOBLAST-LIKE CELLS; IN-VITRO; MORPHOGENETIC PROTEIN; MECHANICAL-PROPERTIES; TISSUE; COMPOSITE; DELIVERY; CALCIFICATION; STERILIZATION; BIOMATERIALS"}]}, "item_6_textarea_68": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "Many recent studies have been conducted to assess the ability of composite materials containing carbon nanotubes (CNTs) with high bone affinity to serve as scaffolds in bone regenerative medicine. These studies have demonstrated that CNTs can effectively induce bone formation. However, no studies have investigated the usefulness of scaffolds consisting exclusively of CNTs in bone regenerative medicine. We built a three-dimensional block entity with maximized mechanical strength from multi-walled CNTs (MWCNT blocks) and evaluated their efficacy as scaffold material for bone repair. When MWCNT blocks containing recombinant human bone morphogenetic protein-2 (rhBMP-2) were implanted in mouse muscle, ectopic bone was formed in direct contact with the blocks. Their bone marrow densities were comparable to those of PET-reinforced collagen sheets with rhBMP-2. On day 1 and day 3, MC3T3-E1 preosteoblasts were attached to the scaffold surface of MWCNT blocks than that of PET-reinforced collagen sheets. They also showed a maximum compression strength comparable to that of cortical bone. Our MWCNT blocks are expected to serve as bone defect filler and scaffold material for bone regeneration."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Tanaka, Manabu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "106573", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sato, Yoshinori", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "106574", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Haniu, Hisao", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "106575", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nomura, Hiroki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "106576", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kobayashi, Shinsuke", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "106577", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takanashi, Seiji", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "106578", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okamoto, Masanori", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "106579", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takizawa, Takashi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "106580", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Aoki, Kaoru", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "106581", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Usui, Yuki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "106582", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Oishi, Ayumu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "106583", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kato, Hiroyuki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "106584", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Saito, Naoto", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "106585", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-10-31"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "journal.pone.0172601.pdf", "filesize": [{"value": "3.1 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "© 2017 Tanaka et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited", "licensetype": "license_note", "mimetype": "application/pdf", "size": 3100000.0, "url": {"label": "journal.pone.0172601.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/20217/files/journal.pone.0172601.pdf"}, "version_id": "d64b859c-e3d4-4ea6-af6c-d952997cef07"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "A three-dimensional block structure consisting exclusively of carbon nanotubes serving as bone regeneration scaffold and as bone defect filler", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "A three-dimensional block structure consisting exclusively of carbon nanotubes serving as bone regeneration scaffold and as bone defect filler", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["462"], "permalink_uri": "http://hdl.handle.net/10091/00020975", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2018-10-31"}, "publish_date": "2018-10-31", "publish_status": "0", "recid": "20217", "relation": {}, "relation_version_is_last": true, "title": ["A three-dimensional block structure consisting exclusively of carbon nanotubes serving as bone regeneration scaffold and as bone defect filler"], "weko_shared_id": -1}
  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

A three-dimensional block structure consisting exclusively of carbon nanotubes serving as bone regeneration scaffold and as bone defect filler

http://hdl.handle.net/10091/00020975
http://hdl.handle.net/10091/00020975
d7b3e066-3e47-44b3-a4e7-61c486e00096
名前 / ファイル ライセンス アクション
journal.pone.0172601.pdf journal.pone.0172601.pdf (3.1 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-10-31
タイトル
言語 en
タイトル A three-dimensional block structure consisting exclusively of carbon nanotubes serving as bone regeneration scaffold and as bone defect filler
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Tanaka, Manabu

× Tanaka, Manabu

WEKO 106573

en Tanaka, Manabu

Search repository
Sato, Yoshinori

× Sato, Yoshinori

WEKO 106574

en Sato, Yoshinori

Search repository
Haniu, Hisao

× Haniu, Hisao

WEKO 106575

en Haniu, Hisao

Search repository
Nomura, Hiroki

× Nomura, Hiroki

WEKO 106576

en Nomura, Hiroki

Search repository
Kobayashi, Shinsuke

× Kobayashi, Shinsuke

WEKO 106577

en Kobayashi, Shinsuke

Search repository
Takanashi, Seiji

× Takanashi, Seiji

WEKO 106578

en Takanashi, Seiji

Search repository
Okamoto, Masanori

× Okamoto, Masanori

WEKO 106579

en Okamoto, Masanori

Search repository
Takizawa, Takashi

× Takizawa, Takashi

WEKO 106580

en Takizawa, Takashi

Search repository
Aoki, Kaoru

× Aoki, Kaoru

WEKO 106581

en Aoki, Kaoru

Search repository
Usui, Yuki

× Usui, Yuki

WEKO 106582

en Usui, Yuki

Search repository
Oishi, Ayumu

× Oishi, Ayumu

WEKO 106583

en Oishi, Ayumu

Search repository
Kato, Hiroyuki

× Kato, Hiroyuki

WEKO 106584

en Kato, Hiroyuki

Search repository
Saito, Naoto

× Saito, Naoto

WEKO 106585

en Saito, Naoto

Search repository
信州大学研究者総覧へのリンク
氏名 Haniu, Hisao
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.jakpPmSa.html
信州大学研究者総覧へのリンク
氏名 Okamoto, Masanori
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.uafabVym.html
信州大学研究者総覧へのリンク
氏名 Aoki, Kaoru
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.WeDpbhym.html
信州大学研究者総覧へのリンク
氏名 Kato, Hiroyuki
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.WVkCbaSp.html
信州大学研究者総覧へのリンク
氏名 Saito, Naoto
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.WpkhuUkh.html
出版者
出版者 PUBLIC LIBRARY SCIENCE
引用
内容記述タイプ Other
内容記述 PLOS ONE.12(2):e0172601(2017)
書誌情報 PLOS ONE

巻 12, 号 2, p. e0172601, 発行日 2017-02-24
抄録
内容記述タイプ Abstract
内容記述 Many recent studies have been conducted to assess the ability of composite materials containing carbon nanotubes (CNTs) with high bone affinity to serve as scaffolds in bone regenerative medicine. These studies have demonstrated that CNTs can effectively induce bone formation. However, no studies have investigated the usefulness of scaffolds consisting exclusively of CNTs in bone regenerative medicine. We built a three-dimensional block entity with maximized mechanical strength from multi-walled CNTs (MWCNT blocks) and evaluated their efficacy as scaffold material for bone repair. When MWCNT blocks containing recombinant human bone morphogenetic protein-2 (rhBMP-2) were implanted in mouse muscle, ectopic bone was formed in direct contact with the blocks. Their bone marrow densities were comparable to those of PET-reinforced collagen sheets with rhBMP-2. On day 1 and day 3, MC3T3-E1 preosteoblasts were attached to the scaffold surface of MWCNT blocks than that of PET-reinforced collagen sheets. They also showed a maximum compression strength comparable to that of cortical bone. Our MWCNT blocks are expected to serve as bone defect filler and scaffold material for bone regeneration.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 1932-6203
PubMed
識別子タイプ PMID
関連識別子 https://www.ncbi.nlm.nih.gov/pubmed/28235026
関連名称 28235026
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1371/journal.pone.0172601
関連名称 10.1371/journal.pone.0172601
権利
権利情報 © 2017 Tanaka et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000394688200098
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 07:23:51.518609
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3