{"_buckets": {"deposit": "7b1ced2e-3cbf-4dcd-a74c-ff6b65193996"}, "_deposit": {"id": "20709", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "20709"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00020709", "sets": []}, "author_link": ["108011"], "item_14_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2019-03-20", "bibliographicIssueDateType": "Issued"}}]}, "item_14_date_granted_8": {"attribute_name": "学位授与年月日", "attribute_value_mlt": [{"subitem_dategranted": "2019-03-20"}]}, "item_14_degree_grantor_10": {"attribute_name": "学位授与機関", "attribute_value_mlt": [{"subitem_degreegrantor": [{"subitem_degreegrantor_name": "信州大学(Shinshu university)"}], "subitem_degreegrantor_identifier": [{"subitem_degreegrantor_identifier_name": "13601", "subitem_degreegrantor_identifier_scheme": "kakenhi"}]}]}, "item_14_degree_name_9": {"attribute_name": "学位名", "attribute_value_mlt": [{"subitem_degreename": "博士（保健学）"}]}, "item_14_description_26": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "雑誌に発表。VETERINARY MICROBIOLOGY. 216:183-189 (2018); doi:10.1016/j.vetmic.2018.02.020.", "subitem_description_type": "Other"}]}, "item_14_description_37": {"attribute_name": "資源タイプ（コンテンツの種類）", "attribute_value_mlt": [{"subitem_description": "Thesis", "subitem_description_type": "Other"}]}, "item_14_description_5": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "前山　佳彦. Prevalence of ESBL/AmpC genes and specific clones among the third-generation cephalosporin-resistant Enterobacteriaceae from canine and feline clinical specimens  in Japan（国内のイヌ及びネコの臨床材料から分離された第三世代セファロスポリン耐性EnterobacteriaceaeにおけるESBL/AmpC遺伝子及び特定クローンの分布）. 信州大学, 2019, 博士論文.", "subitem_description_type": "Other"}]}, "item_14_dissertation_number_7": {"attribute_name": "学位授与番号", "attribute_value_mlt": [{"subitem_dissertationnumber": "13601甲第30号"}]}, "item_14_link_74": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000428487800026"}]}, "item_14_publisher_4": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "信州大学"}]}, "item_14_relation_54": {"attribute_name": "PubMed", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "29519514"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://pubmed.ncbi.nlm.nih.gov/29519514/", "subitem_relation_type_select": "PMID"}}]}, "item_14_relation_55": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1016/j.vetmic.2018.02.020"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1016/j.vetmic.2018.02.020", "subitem_relation_type_select": "DOI"}}]}, "item_14_rights_69": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2018 Elsevier B.V."}]}, "item_14_select_71": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "ETD"}]}, "item_14_text_11": {"attribute_name": "学位の区分", "attribute_value_mlt": [{"subitem_text_value": "doctoral"}]}, "item_14_text_12": {"attribute_name": "学位の分野", "attribute_value_mlt": [{"subitem_text_value": "保健学"}]}, "item_14_text_13": {"attribute_name": "学位の報告番号", "attribute_value_mlt": [{"subitem_text_value": "甲第30号"}]}, "item_14_text_76": {"attribute_name": "wosonly authkey", "attribute_value_mlt": [{"subitem_text_value": "bla(CTX-M-27); ESBL; B2-O25-ST131-H30R; E. coil; K. pneumoniae; Companion animals"}]}, "item_14_text_77": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "PATHOGENIC ESCHERICHIA-COLI; BETA-LACTAMASE GENES; SEQUENCE TYPE 11; COMPANION ANIMALS; EMERGENCE; PLASMIDS; HUMANS; SPREAD; DOGS; CTX-M-15"}]}, "item_14_textarea_75": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "In recent years, besides the widespread occurrence of extended-spectrum beta-lactamase (ESBL)- and/or plasmid-mediated AmpC (pAmpC)-producing Enterobacteriaceae in both healthcare and community settings of humans, the third-generation cephalosporin (3GC)-resistant microbes have also been reported from companion animals worldwide. Here, we characterized ESBL- and/or pAmpC-producing Enterobacteriaceae clinical isolates from companion animals. Among the 487 clinical isolates mainly from urine of dogs and cats between May and September 2016, 104 non-repetitive isolates were resistant to the 3GC, and they consisted of 81 of 381 (21.3%) Escherichia coil, 21 of 50 (42.0%) Klebsiella pneumoniae, and 2 of 56 (3.6%) Proteus mirabilis isolates. In the 81 E. coil, the predominant bla genes were bla(CTX-M-27) and bla(CMY-2) (n = 15 each), followed by bla(CTX-M-15) (n = 14), bla(CTX-M-14) (n = 10), and bla(CTX-M-55) (n = 5). In 21 K. pneumoniae, 10 bIa gene types including bla(CTX-M-15) (n = 4), bla(CTX-M-2) (n = 4), and bla(CTX-M-14) (n = 3) were found. The bla(CTX-M-2) was identified in 2 P. mirabilis. Twenty-four of the 42 E. coil belonging to phylogroup B2 were O25b-ST131 clone, mostly associated with uropathogenic E. coil pathotype, and 22 isolates of this clone were identified as specific H30R subclone. High prevalence of the bla(CTX-M-27)-harboring isolates were noted among the H30R/non-Rx lineage (13/19, 68.4%) (p \u003c 0.05). The genetic environment of bla(CTX-M-27) of most isolates of this lineage was identical to that of human isolates, but unique flanking genetic structures were also identified. Newly emerging virulent lineage B2-non-O25b-ST1193 was also confirmed in 5 isolates. The fosA3 and/or armA genes were detected in E. colt and K. pneumoniae isolates. These data suggest that companion animals serve as a potential reservoir of antimicrobial resistant E. colt and K. pneumoniae. This also has considerable veterinary importance, since urinary tract infections are an important disease causing therapeutic challenges worldwide."}]}, "item_1627890986942": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_be7fb7dd8ff6fe43", "subitem_version_type": "NA"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "前山, 佳彦", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "108011", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-05-22"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "16MK004J_yoshi.pdf", "filesize": [{"value": "163.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 163900.0, "url": {"label": "内容の要旨", "url": "https://soar-ir.repo.nii.ac.jp/record/20709/files/16MK004J_yoshi.pdf"}, "version_id": "5cba65a5-2688-40a6-a581-eb1a57445064"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-05-22"}], "displaytype": "detail", "download_preview_message": "", "file_order": 1, "filename": "16MK004J_shinsa.pdf", "filesize": [{"value": "167.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 167400.0, "url": {"label": "審査結果の要旨", "url": "https://soar-ir.repo.nii.ac.jp/record/20709/files/16MK004J_shinsa.pdf"}, "version_id": "256c04c1-dece-448c-a185-1697860ff21f"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-05-22"}], "displaytype": "detail", "download_preview_message": "", "file_order": 2, "filename": "16MK004J_ronbun.pdf", "filesize": [{"value": "696.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "© 2018 Elsevier B.V.", "licensetype": "license_note", "mimetype": "application/pdf", "size": 696800.0, "url": {"label": "博士論文の全文", "objectType": "fulltext", "url": "https://soar-ir.repo.nii.ac.jp/record/20709/files/16MK004J_ronbun.pdf"}, "version_id": "2b7f2140-a8e7-4bb9-bd0c-dd24b2dc2261"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "doctoral thesis", "resourceuri": "http://purl.org/coar/resource_type/c_db06"}]}, "item_title": "Prevalence of ESBL/AmpC genes and specific clones among the third-generation cephalosporin-resistant Enterobacteriaceae from canine and feline clinical specimens  in Japan（国内のイヌ及びネコの臨床材料から分離された第三世代セファロスポリン耐性EnterobacteriaceaeにおけるESBL/AmpC遺伝子及び特定クローンの分布）", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Prevalence of ESBL/AmpC genes and specific clones among the third-generation cephalosporin-resistant Enterobacteriaceae from canine and feline clinical specimens  in Japan（国内のイヌ及びネコの臨床材料から分離された第三世代セファロスポリン耐性EnterobacteriaceaeにおけるESBL/AmpC遺伝子及び特定クローンの分布）", "subitem_title_language": "en"}]}, "item_type_id": "14", "owner": "1", "path": ["850"], "permalink_uri": "http://hdl.handle.net/10091/00021467", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2019-05-21"}, "publish_date": "2019-05-21", "publish_status": "0", "recid": "20709", "relation": {}, "relation_version_is_last": true, "title": ["Prevalence of ESBL/AmpC genes and specific clones among the third-generation cephalosporin-resistant Enterobacteriaceae from canine and feline clinical specimens  in Japan（国内のイヌ及びネコの臨床材料から分離された第三世代セファロスポリン耐性EnterobacteriaceaeにおけるESBL/AmpC遺伝子及び特定クローンの分布）"], "weko_shared_id": -1}