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Diversity of respiratory impedance based on quantitative computed tomography in patients with COPD(定量CTに基づくCOPD患者における呼吸インピーダンスの多様性). 信州大学, 2019, 博士論文.", "subitem_description_type": "Other"}]}, "item_14_dissertation_number_7": {"attribute_name": "学位授与番号", "attribute_value_mlt": [{"subitem_dissertationnumber": "13601甲第1144号"}]}, "item_14_link_74": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000434032900001"}]}, "item_14_publisher_4": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "信州大学"}]}, "item_14_relation_54": {"attribute_name": "PubMed", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "29892193"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://pubmed.ncbi.nlm.nih.gov/29892193/", "subitem_relation_type_select": "PMID"}}]}, "item_14_relation_55": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.2147/COPD.S163129"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.2147/COPD.S163129", "subitem_relation_type_select": "DOI"}}]}, "item_14_rights_69": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2018 Wada et al. 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Patients and methods: Medical records of 174 stable COPD patients were retrospectively reviewed to obtain the patients\u0027 clinical data, including the pulmonary function and imaging data. According to the software-based quantification of the degree of emphysema and airway wall thickness, the patients were classified into the \"normal by CT\" phenotype, the airway-dominant phenotype, the emphysema-dominant phenotype, and the mixed phenotype. The pulmonary function, including the respiratory impedance evaluated by using the forced oscillation technique (FOT) and the reversibility of airway obstruction in response to inhaled short-acting beta(2)-agonists, was then compared among the four phenotypes. Results: The respiratory system resistance at 5 and 20 Hz (R5 and R20) was significantly higher, and the respiratory system reactance at 5 Hz (X5) was significantly more negative in the airway-dominant and mixed phenotypes than in the other phenotypes. The within-breath changes of X5 (Delta X5) were significantly greater in the mixed phenotype than in the \"normal by CT\" and emphysema-dominant phenotypes. The FOT parameters (R5, R20, and X5) were significantly correlated with indices of the degree of airway wall thickness and significantly but weakly correlated with the reversibility of airway obstruction. There was no significant correlation between the FOT parameters (R5, R20, and X5) and the degree of emphysema. Conclusion: There is a diversity of respiratory physiology, including the respiratory impedance and reversibility of airway obstruction, based on quantitative CT in patients with COPD. 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  1. 050 医学部, 大学院医学系研究科
  2. 0507 学位論文
  3. 博士(医学)

Diversity of respiratory impedance based on quantitative computed tomography in patients with COPD(定量CTに基づくCOPD患者における呼吸インピーダンスの多様性)

http://hdl.handle.net/10091/00021485
http://hdl.handle.net/10091/00021485
617922bf-3668-4068-ac0d-5e6842b72ab2
名前 / ファイル ライセンス アクション
15MH044A_yoshi.pdf 内容の要旨 (146.8 kB)
15MH044A_shinsa.pdf 審査結果の要旨 (111.1 kB)
15MH044A_ronbun.pdf 博士論文の全文 (199.4 kB)
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Item type 学位論文 / Thesis or Dissertation(1)
公開日 2019-06-14
タイトル
言語 en
タイトル Diversity of respiratory impedance based on quantitative computed tomography in patients with COPD(定量CTに基づくCOPD患者における呼吸インピーダンスの多様性)
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_db06
タイプ doctoral thesis
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
著者 和田, 洋典

× 和田, 洋典

WEKO 108063

ja 和田, 洋典

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出版者
出版者 信州大学
引用
内容記述タイプ Other
内容記述 和田 洋典. Diversity of respiratory impedance based on quantitative computed tomography in patients with COPD(定量CTに基づくCOPD患者における呼吸インピーダンスの多様性). 信州大学, 2019, 博士論文.
書誌情報
発行日 2019-03-31
学位授与番号
学位授与番号 13601甲第1144号
学位授与年月日
学位授与年月日 2019-03-31
学位名
学位名 博士(医学)
学位授与機関
学位授与機関識別子Scheme kakenhi
学位授与機関識別子 13601
学位授与機関名 信州大学(Shinshu university)
学位の区分
doctoral
学位の分野
医学
学位の報告番号
甲第1144号
内容記述
内容記述タイプ Other
内容記述 雑誌に発表。INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 13:1841-1849 (2018); doi:10.2147/COPD.S163129.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Thesis
PubMed
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/29892193/
関連名称 29892193
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.2147/COPD.S163129
関連名称 10.2147/COPD.S163129
権利
権利情報 © 2018 Wada et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
出版タイプ
出版タイプ NA
出版タイプResource http://purl.org/coar/version/c_be7fb7dd8ff6fe43
WoS
Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000434032900001
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