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To strive for minimal hemolysis during Dihead CPB, we compared the hemolysis caused by three different suction systems and performed a clinical study with the newly applied suction system. Materials \u0026 Methods: We evaluated the hemolysis caused by roller-pump suction, the SmartSuction((R)) Harmony((R)) and wall suction systems with respect to suction speed and compared the systems by means of in vitro studies. A clinical study was also performed on 15 volunteers to assess hemolysis and the adequacy of the newly applied suction system with Dihead CPB. Results: Pressure inside the suction cannula was -22.5 +/- 0.1 mmHg at a maximum flow of 1.5 L/min for roller-pump suction and -43.4 +/- 0.1 mmHg at -150 mmHg of the set vacuum pressure of wall suction. With the SmartSuction, the pressure inside the cannula varied from -76.3 +/- 1.0 to -130.3 +/- 1.5 mmHg, depending on suctioning conditions. Suction speed (to suction 50 ml of blood) was fastest with the SmartSuction (69.7 +/- 3.58 s) whereas, with roller suction, it was 117.3 +/- 8.47 s and with wall suction 96.9 +/- 7.10 s. The SmartSuction had the highest hemolysis rate (2.00 +/- 0.33%) vs. 0.61 +/- 0.10% for roller suction and 0.41 +/- 0.11% for wall suction (p\u003c0.001). The clinical study with wall suction showed no significant increase in plasma free hemoglobin during or after CPB compared with before surgery. 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  1. 050 医学部, 大学院医学系研究科
  2. 0507 学位論文
  3. 博士(医学)

Hemolytic Characteristics of Three Suctioning Systems for Use with a Newly Developed Cardiopulmonary Bypass System(新しく開発した人工心肺システムで使用する3つの吸引システムの溶血特性に関する研究)

http://hdl.handle.net/10091/00021486
8666d210-b3a8-45e9-b263-96ca46edf37b
名前 / ファイル ライセンス アクション
12MH040H_yoshi.pdf 内容の要旨 (127.8 kB)
12MH040H_shinsa.pdf 審査結果の要旨 (88.8 kB)
12MH040H_ronbun.pdf 博士論文の全文 (433.3 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2019-06-14
タイトル
言語 en
タイトル Hemolytic Characteristics of Three Suctioning Systems for Use with a Newly Developed Cardiopulmonary Bypass System(新しく開発した人工心肺システムで使用する3つの吸引システムの溶血特性に関する研究)
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_db06
タイプ doctoral thesis
著者 道永, 祐希

× 道永, 祐希

WEKO 108064

道永, 祐希

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出版者
出版者 信州大学
引用
内容記述タイプ Other
内容記述 道永 祐希. Hemolytic Characteristics of Three Suctioning Systems for Use with a Newly Developed Cardiopulmonary Bypass System(新しく開発した人工心肺システムで使用する3つの吸引システムの溶血特性に関する研究). 信州大学, 2018, 博士論文.
書誌情報
発行日 2018-09-30
学位授与番号
学位授与番号 13601甲第1145号
学位授与年月日
学位授与年月日 2018-09-30
学位名
学位名 博士(医学)
学位授与機関
学位授与機関名
学位授与機関名 信州大学(Shinshu university)
学位の区分
Doctoral
学位の分野
医学
学位の報告番号
甲第1145号
内容記述
内容記述タイプ Other
内容記述 雑誌に発表。PERFUSION-UK. 34(2):136-142 (2019); doi:10.1177/0267659118793559.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Thesis
PubMed
関連識別子
識別子タイプ PMID
関連識別子 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=30124127
関連名称
関連名称 30124127
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1177/0267659118793559
関連名称
関連名称 10.1177/0267659118793559
権利
権利情報 © 2019, SAGE Publications / The final, definitive version of this paper has been published in PERFUSION, 34/2, 2018 by SAGE Publications Ltd, All rights reserved.
出版タイプ
出版タイプ NA
出版タイプResource http://purl.org/coar/version/c_be7fb7dd8ff6fe43
WoS
Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000458887400007
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