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However, physiological and immunological mechanisms in support of this practice are unknown. Therefore, we conducted rat and rabbit in vivo experiments to investigate the effects of intragastric administration of distilled water on the jejunal-originated lymph flow and the concentrations and total flux of cells, albumin, long-chain fatty acids, and innate lymphoid cell 3 (ILC-3)-secreted interleukin-22 (IL-22) through mesenteric lymph vessels. The distribution and activity of ILC-3 in rat small intestine by water intake were evaluated using flow cytometry and RT-PCR. The intragastric administration of distilled water caused significant increases in rat mesenteric lymph flow and in the total flux of cells, albumin, long-chain fatty acids, and IL-22 through the lymph vessels. Intravenously injected Evans blue dye was rapidly transported into rabbit mesenteric lymph vessel and cisterna chyli. 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  1. 050 医学部, 大学院医学系研究科
  2. 0507 学位論文
  3. 博士(医学)

Water intake increases mesenteric lymph flow and the total flux of albumin,long-chain fatty acids, and IL-22 in rats: New concept of absorption in jejunum(水の摂取によりラットの腸管膜リンパ流量とアルブミン,長鎖脂肪酸,IL-22の総量が増加する;空腸における吸収の生理機能の新概念)

http://hdl.handle.net/10091/00021499
4959f412-7e84-4086-8175-edb5493480ca
名前 / ファイル ライセンス アクション
16MH024A_yoshi.pdf 内容の要旨 (139.1 kB)
16MH024A_shinsa.pdf 審査結果の要旨 (104.4 kB)
16MH024A_ronbun.pdf 博士論文の全文 (3.2 MB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2019-06-14
タイトル
言語 en
タイトル Water intake increases mesenteric lymph flow and the total flux of albumin,long-chain fatty acids, and IL-22 in rats: New concept of absorption in jejunum(水の摂取によりラットの腸管膜リンパ流量とアルブミン,長鎖脂肪酸,IL-22の総量が増加する;空腸における吸収の生理機能の新概念)
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_db06
タイプ doctoral thesis
著者 長汐, 沙千穂

× 長汐, 沙千穂

WEKO 108077

長汐, 沙千穂

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出版者
出版者 信州大学
引用
内容記述タイプ Other
内容記述 長汐 沙千穂. Water intake increases mesenteric lymph flow and the total flux of albumin,long-chain fatty acids, and IL-22 in rats: New concept of absorption in jejunum(水の摂取によりラットの腸管膜リンパ流量とアルブミン,長鎖脂肪酸,IL-22の総量が増加する;空腸における吸収の生理機能の新概念). 信州大学, 2019, 博士論文.
書誌情報
発行日 2019-03-31
学位授与番号
学位授与番号 13601甲第1158号
学位授与年月日
学位授与年月日 2019-03-31
学位名
学位名 博士(医学)
学位授与機関
学位授与機関名
学位授与機関名 信州大学(Shinshu university)
学位の区分
Doctoral
学位の分野
医学
学位の報告番号
甲第1158号
内容記述
内容記述タイプ Other
内容記述 雑誌に発表。AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY. 316(1):G155-G165 (2019); doi:10.1152/ajpgi.00325.2018.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Thesis
PubMed
関連識別子
識別子タイプ PMID
関連識別子 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=30431330
関連名称
関連名称 30431330
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1152/ajpgi.00325.2018
関連名称
関連名称 10.1152/ajpgi.00325.2018
権利
権利情報 © 2019 the American Physiological Society
出版タイプ
出版タイプ NA
出版タイプResource http://purl.org/coar/version/c_be7fb7dd8ff6fe43
WoS
Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000455670700009
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