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Watertight Robust Osteoconductive Barrier For Complex Skull Base Reconstruction: An Expanded-Endoscopic Endonasal Experimental Study.(WROバリヤー:広範頭蓋底腫瘍に対する経鼻内視鏡手術における新たな頭蓋底再建法). 信州大学, 2019, 博士論文.", "subitem_description_type": "Other"}]}, "item_14_dissertation_number_7": {"attribute_name": "学位授与番号", "attribute_value_mlt": [{"subitem_dissertationnumber": "13601甲第1161号"}]}, "item_14_link_74": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000462817600002"}]}, "item_14_publisher_4": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "信州大学"}]}, "item_14_relation_54": {"attribute_name": "PubMed", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "30787233"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://pubmed.ncbi.nlm.nih.gov/30787233/", "subitem_relation_type_select": "PMID"}}]}, "item_14_relation_55": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.2176/nmc.oa.2018-0262"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.2176/nmc.oa.2018-0262", "subitem_relation_type_select": "DOI"}}]}, "item_14_rights_69": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2019 by The Japan Neurosurgical Society / This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives International License."}]}, "item_14_select_71": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "ETD"}]}, "item_14_text_11": {"attribute_name": "学位の区分", "attribute_value_mlt": [{"subitem_text_value": "doctoral"}]}, "item_14_text_12": {"attribute_name": "学位の分野", "attribute_value_mlt": [{"subitem_text_value": "医学"}]}, "item_14_text_13": {"attribute_name": "学位の報告番号", "attribute_value_mlt": [{"subitem_text_value": "甲第1161号"}]}, "item_14_text_76": {"attribute_name": "wosonly authkey", "attribute_value_mlt": [{"subitem_text_value": "skull base reconstruction; endoscopic endonasal approach; CSF leak; transsphenoidal surgery; watertight"}]}, "item_14_text_77": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "CEREBROSPINAL-FLUID LEAK; BONE-CEMENT; FIBRIN GLUE; SELLAR REPAIR; RISK-FACTORS; FLAP; OUTCOMES; DEFECTS; SURGERY; PEDICLE"}]}, "item_14_textarea_75": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "Endoscopic skull base reconstruction (ESBR) following expanded-endoscopic endonasal approaches (EEA) in high-risk non-ideal endoscopic reconstructive candidates remains extremely challenging, and further innovations are still necessary. Here, the aim is to study the reconstructive knowledge gap following expanded-EEA and to introduce the watertight robust osteoconductive (WRO)-barrier as an alternative durable option. Distinctively, we focused on 10 clinical circumstances. A 3D-skull base-water system model was innovated to investigate the ESBR under realistic conditions. A large-irregular defect (31 x 89 mm) extending from the crista galli to the mid-clivus was achieved. Then, WRO-barrier was fashioned and its tolerance was evaluated under stressful settings, including an exceedingly high (55 cmH(2)O) pressure, with radiological assessment. Next, the whole WRO-barrier was drilled to examine its practical-safe removal (simulating redo-EEA) and the whole experiment was repeated. Finally, WRO-barrier was kept into place to value its 18-month long-term high-tolerance. Results in all experiments of WRO-barriers were satisfactorily fashioned to conform the geometry of the created defect under realistic circumstances via EEA, tolerated an exceedingly high pressure without evidence of leak even under stressful settings, resisted sudden-elevated pressure, and remained in its position to maintain long-term watertight seal (18 months), efficiently evaluated with neuroimaging and simply removed-and-reconstructed when redo-EEA is needed. In conclusion, WRO-barrier as an osteoconductive watertight robust design for cranial base reconstruction possesses several distinct qualities that might be beneficial for patients with complex skull base tumours."}]}, "item_1627890986942": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_be7fb7dd8ff6fe43", "subitem_version_type": "NA"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "NAGM, ALHUSAIN", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "108080", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-06-13"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "15MH030A_yoshi.pdf", "filesize": [{"value": "132.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 132800.0, "url": {"label": "内容の要旨", "url": "https://soar-ir.repo.nii.ac.jp/record/20744/files/15MH030A_yoshi.pdf"}, "version_id": "59d9547a-b382-4356-8791-47dbb9a406de"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-06-13"}], "displaytype": "detail", "download_preview_message": "", "file_order": 1, "filename": "15MH030A_shinsa.pdf", "filesize": [{"value": "108.6 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 108600.0, "url": {"label": "審査結果の要旨", "url": "https://soar-ir.repo.nii.ac.jp/record/20744/files/15MH030A_shinsa.pdf"}, "version_id": "f096f312-e1bf-4d36-b130-426986878d69"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-06-13"}], "displaytype": "detail", "download_preview_message": "", "file_order": 2, "filename": "15MH030A_ronbun.pdf", "filesize": [{"value": "2.7 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_11", "mimetype": "application/pdf", "size": 2700000.0, "url": {"label": "博士論文の全文", "objectType": "fulltext", "url": "https://soar-ir.repo.nii.ac.jp/record/20744/files/15MH030A_ronbun.pdf"}, "version_id": "218a41b5-454d-4946-b893-82baaef9db30"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "doctoral thesis", "resourceuri": "http://purl.org/coar/resource_type/c_db06"}]}, "item_title": "Watertight Robust Osteoconductive Barrier For Complex Skull Base Reconstruction: An Expanded-Endoscopic Endonasal Experimental Study.(WROバリヤー:広範頭蓋底腫瘍に対する経鼻内視鏡手術における新たな頭蓋底再建法)", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Watertight Robust Osteoconductive Barrier For Complex Skull Base Reconstruction: An Expanded-Endoscopic Endonasal Experimental Study.(WROバリヤー:広範頭蓋底腫瘍に対する経鼻内視鏡手術における新たな頭蓋底再建法)", "subitem_title_language": "en"}]}, "item_type_id": "14", "owner": "1", "path": ["849"], "permalink_uri": "http://hdl.handle.net/10091/00021502", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2019-06-14"}, "publish_date": "2019-06-14", "publish_status": "0", "recid": "20744", "relation": {}, "relation_version_is_last": true, "title": ["Watertight Robust Osteoconductive Barrier For Complex Skull Base Reconstruction: An Expanded-Endoscopic Endonasal Experimental Study.(WROバリヤー:広範頭蓋底腫瘍に対する経鼻内視鏡手術における新たな頭蓋底再建法)"], "weko_shared_id": -1}
Watertight Robust Osteoconductive Barrier For Complex Skull Base Reconstruction: An Expanded-Endoscopic Endonasal Experimental Study.(WROバリヤー:広範頭蓋底腫瘍に対する経鼻内視鏡手術における新たな頭蓋底再建法)
http://hdl.handle.net/10091/00021502
http://hdl.handle.net/10091/0002150231fe1b24-5b0c-454c-8e2c-cef5fa5cdf00
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内容の要旨 (132.8 kB)
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審査結果の要旨 (108.6 kB)
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博士論文の全文 (2.7 MB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2019-06-14 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Watertight Robust Osteoconductive Barrier For Complex Skull Base Reconstruction: An Expanded-Endoscopic Endonasal Experimental Study.(WROバリヤー:広範頭蓋底腫瘍に対する経鼻内視鏡手術における新たな頭蓋底再建法) | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_db06 | |||||
タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
NAGM, ALHUSAIN
× NAGM, ALHUSAIN |
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出版者 | ||||||
出版者 | 信州大学 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | NAGM ALHUSAIN. Watertight Robust Osteoconductive Barrier For Complex Skull Base Reconstruction: An Expanded-Endoscopic Endonasal Experimental Study.(WROバリヤー:広範頭蓋底腫瘍に対する経鼻内視鏡手術における新たな頭蓋底再建法). 信州大学, 2019, 博士論文. | |||||
書誌情報 |
発行日 2019-03-31 |
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学位授与番号 | ||||||
学位授与番号 | 13601甲第1161号 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2019-03-31 | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 13601 | |||||
学位授与機関名 | 信州大学(Shinshu university) | |||||
学位の区分 | ||||||
doctoral | ||||||
学位の分野 | ||||||
医学 | ||||||
学位の報告番号 | ||||||
甲第1161号 | ||||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 雑誌に発表。NEUROLOGIA MEDICO-CHIRURGICA. 59(3):79-88 (2019); doi:10.2176/nmc.oa.2018-0262. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Thesis | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | https://pubmed.ncbi.nlm.nih.gov/30787233/ | |||||
関連名称 | 30787233 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.2176/nmc.oa.2018-0262 | |||||
関連名称 | 10.2176/nmc.oa.2018-0262 | |||||
権利 | ||||||
権利情報 | © 2019 by The Japan Neurosurgical Society / This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives International License. | |||||
出版タイプ | ||||||
出版タイプ | NA | |||||
出版タイプResource | http://purl.org/coar/version/c_be7fb7dd8ff6fe43 | |||||
WoS | ||||||
Web of Science | ||||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000462817600002 |