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This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/. This is a non-final version of an article published in final form in Int. J. 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Previous reports indicated that negative D-dimer patients have shorter dissection length. However, whether patients with negative D-dimer results have a good prognosis is unknown. This study aimed to elucidate the clinical characteristics and implications of a negative D-dimer result on AAD diagnosis. Methods: The study group comprised 126 patients (71 males, 55 females; mean age, 69 +/- 11 years) with AAD admitted to our hospital between April 2009 and March 2015. Blood samples on presentation were used fur D-dimer measurement. Clinical characteristics and outcomes were assessed. Results: Nine (7.1%) and 117 (92.9%) exhibited negative and positive D-dimer results, respectively. The negative group showed a significantly lower extension score and a higher platelet count than the positive group. Multivariate analysis demonstrated that platelet count (odds ratio, 1.31 (1.09-1.58), p = 0.003) and extension score (odds ratio, 0.56 (0.33-0.96), p = 0.03) were significantly related to a negative result. Notably, 44% of patients in the negative group had type A dissection and 33% underwent an emergency operation due to cardiac tamponade. Conclusion: We found that high platelet count and low extension score were independent factors related to a negative D-dimer result. Even if the length of the dissection is short, an emergency operation is necessary in some patients with a negative D-dimer result. Physicians should recognize that a negative D-dimer result alone cannot exclude patients with fatal AAD conditions. (C) 2017 Elsevier B.V. All rights reserved."}]}, "item_1627890986942": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_be7fb7dd8ff6fe43", "subitem_version_type": "NA"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "新田, 憲市", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "108098", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-06-13"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "18MR0002_yoshi.pdf", "filesize": [{"value": "155.2 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 155200.0, "url": {"label": "内容の要旨", "url": "https://soar-ir.repo.nii.ac.jp/record/20762/files/18MR0002_yoshi.pdf"}, "version_id": "56ef5ed4-c3d5-422e-b6eb-6f13ed4a1cf4"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-06-13"}], "displaytype": "detail", "download_preview_message": "", "file_order": 1, "filename": "18MR0002_shinsa.pdf", "filesize": [{"value": "92.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 92800.0, "url": {"label": "審査結果の要旨", "url": "https://soar-ir.repo.nii.ac.jp/record/20762/files/18MR0002_shinsa.pdf"}, "version_id": "777dc44a-2a6c-4667-9b60-f8181345631a"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-06-13"}], "displaytype": "detail", "download_preview_message": "", "file_order": 2, "filename": "18MR0002_ronbun.pdf", "filesize": [{"value": "107.0 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_11", "mimetype": "application/pdf", "size": 107000.0, "url": {"label": "博士論文の全文", "objectType": "fulltext", "url": "https://soar-ir.repo.nii.ac.jp/record/20762/files/18MR0002_ronbun.pdf"}, "version_id": "91991ba9-2b15-4305-809b-1873295ce23f"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "doctoral thesis", "resourceuri": "http://purl.org/coar/resource_type/c_db06"}]}, "item_title": "Impact of a negative D-dimer result on the initial assessment of acute aortic dissection(急性大動脈解離の初期評価におけるD-dimer陰性の影響)", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Impact of a negative D-dimer result on the initial assessment of acute aortic dissection(急性大動脈解離の初期評価におけるD-dimer陰性の影響)", "subitem_title_language": "en"}]}, "item_type_id": "14", "owner": "1", "path": ["849"], "permalink_uri": "http://hdl.handle.net/10091/00021520", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2019-06-14"}, "publish_date": "2019-06-14", "publish_status": "0", "recid": "20762", "relation": {}, "relation_version_is_last": true, "title": ["Impact of a negative D-dimer result on the initial assessment of acute aortic dissection(急性大動脈解離の初期評価におけるD-dimer陰性の影響)"], "weko_shared_id": -1}
Impact of a negative D-dimer result on the initial assessment of acute aortic dissection(急性大動脈解離の初期評価におけるD-dimer陰性の影響)
http://hdl.handle.net/10091/00021520
http://hdl.handle.net/10091/000215208799e5eb-ff48-4172-ab05-e5fe5b98d296
名前 / ファイル | ライセンス | アクション |
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2019-06-14 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Impact of a negative D-dimer result on the initial assessment of acute aortic dissection(急性大動脈解離の初期評価におけるD-dimer陰性の影響) | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_db06 | |||||
タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
新田, 憲市
× 新田, 憲市 |
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出版者 | ||||||
出版者 | 信州大学 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 新田 憲市. Impact of a negative D-dimer result on the initial assessment of acute aortic dissection(急性大動脈解離の初期評価におけるD-dimer陰性の影響). 信州大学, 2018, 博士論文. | |||||
書誌情報 |
発行日 2018-07-11 |
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学位授与番号 | ||||||
学位授与番号 | 13601乙第1218号 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2018-07-11 | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 13601 | |||||
学位授与機関名 | 信州大学(Shinshu university) | |||||
学位の区分 | ||||||
doctoral | ||||||
学位の分野 | ||||||
医学 | ||||||
学位の報告番号 | ||||||
乙第1218号 | ||||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 雑誌に発表。INTERNATIONAL JOURNAL OF CARDIOLOGY. 258:232-236 (2018); doi:10.1016/j.ijcard.2018.01.104. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Thesis | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | https://pubmed.ncbi.nlm.nih.gov/29422267/ | |||||
関連名称 | 29422267 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.ijcard.2018.01.104 | |||||
関連名称 | 10.1016/j.ijcard.2018.01.104 | |||||
権利 | ||||||
権利情報 | © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/. This is a non-final version of an article published in final form in Int. J. Cardiol., 258: 232-236. | |||||
出版タイプ | ||||||
出版タイプ | NA | |||||
出版タイプResource | http://purl.org/coar/version/c_be7fb7dd8ff6fe43 | |||||
WoS | ||||||
Web of Science | ||||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000427605700051 |