ログイン
言語:

WEKO3

  • トップ
  • コミュニティ
  • ランキング
AND
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "3f251e80-ca03-49c2-9b80-3e3de975339a"}, "_deposit": {"id": "21362", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "21362"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00021362", "sets": []}, "author_link": ["109453"], "item_14_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2019-03-31", "bibliographicIssueDateType": "Issued"}}]}, "item_14_date_granted_8": {"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u5e74\u6708\u65e5", "attribute_value_mlt": [{"subitem_dategranted": "2019-03-31"}]}, "item_14_degree_grantor_10": {"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u6a5f\u95a2", "attribute_value_mlt": [{"subitem_degreegrantor": [{"subitem_degreegrantor_name": "\u4fe1\u5dde\u5927\u5b66(Shinshu university)"}]}]}, "item_14_degree_name_9": {"attribute_name": "\u5b66\u4f4d\u540d", "attribute_value_mlt": [{"subitem_degreename": "\u535a\u58eb\uff08\u4fdd\u5065\u5b66\uff09"}]}, "item_14_description_26": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u96d1\u8a8c\u306b\u767a\u8868\u3002ANNALS OF CLINICAL BIOCHEMISTRY. 56(5):574-582 (2019); doi:10.1177/0004563219849077.", "subitem_description_type": "Other"}]}, "item_14_description_37": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7\uff08\u30b3\u30f3\u30c6\u30f3\u30c4\u306e\u7a2e\u985e\uff09", "attribute_value_mlt": [{"subitem_description": "Thesis", "subitem_description_type": "Other"}]}, "item_14_description_5": {"attribute_name": "\u5f15\u7528", "attribute_value_mlt": [{"subitem_description": "\u5800\u3000\u6566\u8a5e. Characterization of galactosyl and lactosyl sulfatide species in human serum by MALDI-TOF mass spectrometry \uff08\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u652f\u63f4\u30ec\u30fc\u30b6\u30fc\u8131\u96e2\u30a4\u30aa\u30f3\u5316\u98db\u884c\u6642\u9593\u578b\uff08MALDI-TOF\uff09\u8cea\u91cf\u5206\u6790\u306b\u3088\u308b\u30d2\u30c8\u8840\u6e05\u4e2d\u30ac\u30e9\u30af\u30c8\u30b7\u30eb\u30b9\u30eb\u30d5\u30a1\u30c1\u30c9\u5206\u5b50\u7a2e\u3068\u30e9\u30af\u30c8\u30b7\u30eb\u30b9\u30eb\u30d5\u30a1\u30c1\u30c9\u5206\u5b50\u7a2e\u306e\u7279\u5fb4\u4ed8\u3051\uff09. \u4fe1\u5dde\u5927\u5b66, 2019, \u535a\u58eb\u8ad6\u6587.", "subitem_description_type": "Other"}]}, "item_14_dissertation_number_7": {"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u756a\u53f7", "attribute_value_mlt": [{"subitem_dissertationnumber": "13601\u7532\u7b2c32\u53f7"}]}, "item_14_link_74": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000479257000007"}]}, "item_14_publisher_4": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u4fe1\u5dde\u5927\u5b66"}]}, "item_14_relation_54": {"attribute_name": "PubMed", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "31037952"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search\u0026DB=pubmed\u0026term=31037952", "subitem_relation_type_select": "PMID"}}]}, "item_14_relation_55": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1177/0004563219849077"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1177/0004563219849077", "subitem_relation_type_select": "DOI"}}]}, "item_14_rights_69": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "Hori A, Yamaura M, Morita S, Uehara T, Honda T, Hidaka H, Characterization of galactosyl and lactosyl sulfatide species in human serum by MALDI-TOF mass spectrometry, Ann Clin Biochem. 56(5):574\u2010582. Copyright \u00a9 The Author(s) 2019. DOI: 10.1177/0004563219849077."}]}, "item_14_select_71": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "ETD"}]}, "item_14_text_11": {"attribute_name": "\u5b66\u4f4d\u306e\u533a\u5206", "attribute_value_mlt": [{"subitem_text_value": "Doctoral"}]}, "item_14_text_12": {"attribute_name": "\u5b66\u4f4d\u306e\u5206\u91ce", "attribute_value_mlt": [{"subitem_text_value": "\u4fdd\u5065\u5b66"}]}, "item_14_text_13": {"attribute_name": "\u5b66\u4f4d\u306e\u5831\u544a\u756a\u53f7", "attribute_value_mlt": [{"subitem_text_value": "\u7532\u7b2c32\u53f7"}]}, "item_14_text_76": {"attribute_name": "wosonly authkey", "attribute_value_mlt": [{"subitem_text_value": "Mass spectrometry; sphingolipid; sulfatide; hydroxy fatty acid; serum lipids; sphingoid molecule; galactosyl sulfatide; lactosyl sulfatide; very long chain fatty acid; hydroxy fatty acid"}]}, "item_14_text_77": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "CELLS; GLYCOSPHINGOLIPIDS; CANCER; BRAIN"}]}, "item_14_textarea_75": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "Background Sulfatides are found in a variety of tissues and serum lipoproteins. Sulfatide is a molecular species composed of various sphingoid bases, fatty acids and sugar chains; therefore, rapid analysis of the qualitative structure is important in clinical assessment. Methods In this study, sulfatide-rich fractions were isolated from serum lipids, and the sulfatide species were analysed by negative ion mode using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). Results Sulfatide species identified in human serum included two different sugar chains, eight sphingoid molecules and various fatty acid side chains including hydroxy fatty acids. In total, 64 galactosyl sulfatides (SM4s) and 49 lactosyl sulfatides (SM3) were identified. Quantitatively, the amount of SM3 was less than 1% of the amount of SM4s. The fatty acids of SM4s of healthy serum (n = 8) were predominantly C16:0 and a hydroxylation C16:0 (C16:0h), followed by very long chain fatty acids (VLCFAs) predominant species, and SM3 was a major component of VLCFAs. Conclusion This present study described a simple method of human serum sulfatide analysis using MALDI-TOF MS. This method is suitable for clinical laboratories and is likely to increase the understanding of the roles of sulfatide species in both physiological and disease states."}]}, "item_1627890986942": {"attribute_name": "\u51fa\u7248\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_be7fb7dd8ff6fe43", "subitem_version_type": "NA"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u5800, \u6566\u8a5e"}], "nameIdentifiers": [{"nameIdentifier": "109453", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-06-03"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "16MK003A_yoshi.pdf", "filesize": [{"value": "184.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 184300.0, "url": {"label": "\u5185\u5bb9\u306e\u8981\u65e8", "url": "https://soar-ir.repo.nii.ac.jp/record/21362/files/16MK003A_yoshi.pdf"}, "version_id": "6c299c49-a0d7-4173-9d1c-c50cb99aeb0a"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-06-03"}], "displaytype": "detail", "download_preview_message": "", "file_order": 1, "filename": "16MK003A_shinsa.pdf", "filesize": [{"value": "141.1 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 141100.0, "url": {"label": "\u5be9\u67fb\u7d50\u679c\u306e\u8981\u65e8", "url": "https://soar-ir.repo.nii.ac.jp/record/21362/files/16MK003A_shinsa.pdf"}, "version_id": "926940e7-21d3-4699-9564-153962590a34"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-06-25"}], "displaytype": "detail", "download_preview_message": "", "file_order": 2, "filename": "16MK003A_ronbun2.pdf", "filesize": [{"value": "774.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "Hori A, Yamaura M, Morita S, Uehara T, Honda T, Hidaka H, Characterization of galactosyl and lactosyl sulfatide species in human serum by MALDI-TOF mass spectrometry, Ann Clin Biochem. 56(5):574\u2010582. Copyright \u00a9 The Author(s) 2019. DOI: 10.1177/0004563219849077.\u003cbr/\u003e", "licensetype": "license_note", "mimetype": "application/pdf", "size": 774300.0, "url": {"label": "\u535a\u58eb\u8ad6\u6587\u306e\u5168\u6587", "url": "https://soar-ir.repo.nii.ac.jp/record/21362/files/16MK003A_ronbun2.pdf"}, "version_id": "77a43b4c-5729-4f61-8fe6-b840ff3f571d"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "doctoral thesis", "resourceuri": "http://purl.org/coar/resource_type/c_db06"}]}, "item_title": "Characterization of galactosyl and lactosyl sulfatide species in human serum by MALDI-TOF mass spectrometry \uff08\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u652f\u63f4\u30ec\u30fc\u30b6\u30fc\u8131\u96e2\u30a4\u30aa\u30f3\u5316\u98db\u884c\u6642\u9593\u578b\uff08MALDI-TOF\uff09\u8cea\u91cf\u5206\u6790\u306b\u3088\u308b\u30d2\u30c8\u8840\u6e05\u4e2d\u30ac\u30e9\u30af\u30c8\u30b7\u30eb\u30b9\u30eb\u30d5\u30a1\u30c1\u30c9\u5206\u5b50\u7a2e\u3068\u30e9\u30af\u30c8\u30b7\u30eb\u30b9\u30eb\u30d5\u30a1\u30c1\u30c9\u5206\u5b50\u7a2e\u306e\u7279\u5fb4\u4ed8\u3051\uff09", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Characterization of galactosyl and lactosyl sulfatide species in human serum by MALDI-TOF mass spectrometry \uff08\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u652f\u63f4\u30ec\u30fc\u30b6\u30fc\u8131\u96e2\u30a4\u30aa\u30f3\u5316\u98db\u884c\u6642\u9593\u578b\uff08MALDI-TOF\uff09\u8cea\u91cf\u5206\u6790\u306b\u3088\u308b\u30d2\u30c8\u8840\u6e05\u4e2d\u30ac\u30e9\u30af\u30c8\u30b7\u30eb\u30b9\u30eb\u30d5\u30a1\u30c1\u30c9\u5206\u5b50\u7a2e\u3068\u30e9\u30af\u30c8\u30b7\u30eb\u30b9\u30eb\u30d5\u30a1\u30c1\u30c9\u5206\u5b50\u7a2e\u306e\u7279\u5fb4\u4ed8\u3051\uff09", "subitem_title_language": "en"}]}, "item_type_id": "14", "owner": "1", "path": ["461/848/850"], "permalink_uri": "http://hdl.handle.net/10091/00022119", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2020-06-03"}, "publish_date": "2020-06-03", "publish_status": "0", "recid": "21362", "relation": {}, "relation_version_is_last": true, "title": ["Characterization of galactosyl and lactosyl sulfatide species in human serum by MALDI-TOF mass spectrometry \uff08\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u652f\u63f4\u30ec\u30fc\u30b6\u30fc\u8131\u96e2\u30a4\u30aa\u30f3\u5316\u98db\u884c\u6642\u9593\u578b\uff08MALDI-TOF\uff09\u8cea\u91cf\u5206\u6790\u306b\u3088\u308b\u30d2\u30c8\u8840\u6e05\u4e2d\u30ac\u30e9\u30af\u30c8\u30b7\u30eb\u30b9\u30eb\u30d5\u30a1\u30c1\u30c9\u5206\u5b50\u7a2e\u3068\u30e9\u30af\u30c8\u30b7\u30eb\u30b9\u30eb\u30d5\u30a1\u30c1\u30c9\u5206\u5b50\u7a2e\u306e\u7279\u5fb4\u4ed8\u3051\uff09"], "weko_shared_id": -1}
  1. 050 医学部, 大学院医学系研究科
  2. 0507 学位論文
  3. 博士(保健学)

Characterization of galactosyl and lactosyl sulfatide species in human serum by MALDI-TOF mass spectrometry (マトリックス支援レーザー脱離イオン化飛行時間型(MALDI-TOF)質量分析によるヒト血清中ガラクトシルスルファチド分子種とラクトシルスルファチド分子種の特徴付け)

http://hdl.handle.net/10091/00022119
efd4c015-000f-4ee2-8848-ab6ef9ad63ae
名前 / ファイル ライセンス アクション
16MK003A_yoshi.pdf 内容の要旨 (184.3 kB)
16MK003A_shinsa.pdf 審査結果の要旨 (141.1 kB)
16MK003A_ronbun2.pdf 博士論文の全文 (774.3 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2020-06-03
タイトル
言語 en
タイトル Characterization of galactosyl and lactosyl sulfatide species in human serum by MALDI-TOF mass spectrometry (マトリックス支援レーザー脱離イオン化飛行時間型(MALDI-TOF)質量分析によるヒト血清中ガラクトシルスルファチド分子種とラクトシルスルファチド分子種の特徴付け)
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_db06
タイプ doctoral thesis
著者 堀, 敦詞

× 堀, 敦詞

WEKO 109453

堀, 敦詞

Search repository
出版者
出版者 信州大学
引用
内容記述タイプ Other
内容記述 堀 敦詞. Characterization of galactosyl and lactosyl sulfatide species in human serum by MALDI-TOF mass spectrometry (マトリックス支援レーザー脱離イオン化飛行時間型(MALDI-TOF)質量分析によるヒト血清中ガラクトシルスルファチド分子種とラクトシルスルファチド分子種の特徴付け). 信州大学, 2019, 博士論文.
書誌情報
発行日 2019-03-31
学位授与番号
学位授与番号 13601甲第32号
学位授与年月日
学位授与年月日 2019-03-31
学位名
学位名 博士(保健学)
学位授与機関
学位授与機関名
学位授与機関名 信州大学(Shinshu university)
学位の区分
Doctoral
学位の分野
保健学
学位の報告番号
甲第32号
内容記述
内容記述タイプ Other
内容記述 雑誌に発表。ANNALS OF CLINICAL BIOCHEMISTRY. 56(5):574-582 (2019); doi:10.1177/0004563219849077.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Thesis
PubMed
関連識別子
識別子タイプ PMID
関連識別子 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=31037952
関連名称
関連名称 31037952
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1177/0004563219849077
関連名称
関連名称 10.1177/0004563219849077
権利
権利情報 Hori A, Yamaura M, Morita S, Uehara T, Honda T, Hidaka H, Characterization of galactosyl and lactosyl sulfatide species in human serum by MALDI-TOF mass spectrometry, Ann Clin Biochem. 56(5):574‐582. Copyright © The Author(s) 2019. DOI: 10.1177/0004563219849077.
出版タイプ
出版タイプ NA
出版タイプResource http://purl.org/coar/version/c_be7fb7dd8ff6fe43
WoS
Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000479257000007
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 07:31:11.256448
Show All versions

Share

Mendeley CiteULike Twitter Facebook Print Addthis

Cite as

Export

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by CERN Data Centre & Invenio


Powered by CERN Data Centre & Invenio