WEKO3
-
RootNode
アイテム
Cellular Responses of Human Lymphatic Endothelial Cells to Carbon Nanomaterials
http://hdl.handle.net/10091/00022489
http://hdl.handle.net/10091/000224893bd0c145-9322-4bcc-af4f-808148e04bfd
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
nanomaterials-10-01374.pdf (9.9 MB)
|
|
| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2021-02-04 | |||||||||||||||||||||||||||
| タイトル | ||||||||||||||||||||||||||||
| タイトル | Cellular Responses of Human Lymphatic Endothelial Cells to Carbon Nanomaterials | |||||||||||||||||||||||||||
| 言語 | ||||||||||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||||||||||
| DOI | ||||||||||||||||||||||||||||
| 関連識別子 | https://doi.org/10.3390/nano10071374 | |||||||||||||||||||||||||||
| 関連名称 | 10.3390/nano10071374 | |||||||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||||||
| 主題 | carbon nanohorn, carbon black, multi-walled carbon nanotube, lymphatic endothelial cells, cytotoxicity, cellular response | |||||||||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||||||||
| タイプ | journal article | |||||||||||||||||||||||||||
| 著者 |
Sano, Mahoko
× Sano, Mahoko
× Izumiya, Makoto
× Haniu, Hisao
× Ueda, Katsuya
× Konishi, Kosuke
× Ishida, Haruka
× Kuroda, Chika
× Uemura, Takeshi
× Aoki, Kaoru
× Matsuda, Yoshikazu
× Saito, Naoto
|
|||||||||||||||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||||||||||||||
| 氏名 | Haniu, Hisao | |||||||||||||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.jakpPmSa.html | |||||||||||||||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||||||||||||||
| 氏名 | Uemura, Takeshi | |||||||||||||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.HmANWayV.html | |||||||||||||||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||||||||||||||
| 氏名 | Aoki, Kaoru | |||||||||||||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.WeDpbhym.html | |||||||||||||||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||||||||||||||
| 氏名 | Saito, Naoto | |||||||||||||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.WpkhuUkh.html | |||||||||||||||||||||||||||
| 出版者 | ||||||||||||||||||||||||||||
| 出版者 | MDPI | |||||||||||||||||||||||||||
| 引用 | ||||||||||||||||||||||||||||
| 内容記述 | NANOMATERIALS. 10(7):1374 (2020) | |||||||||||||||||||||||||||
| 書誌情報 |
NANOMATERIALS 巻 10, 号 7, p. 1374, 発行日 2020-07 |
|||||||||||||||||||||||||||
| 抄録 | ||||||||||||||||||||||||||||
| 内容記述 | One of the greatest challenges to overcome in the pursuit of the medical application of carbon nanomaterials (CNMs) is safety. Particularly, when considering the use of CNMs in drug delivery systems (DDSs), evaluation of safety at the accumulation site is an essential step. In this study, we evaluated the toxicity of carbon nanohorns (CNHs), which are potential DDSs, using human lymph node endothelial cells that have been reported to accumulate CNMs, as a comparison to fibrous, multi-walled carbon nanotubes (MWCNTs) and particulate carbon black (CB). The effect of different surface characteristics was also evaluated using two types of CNHs (untreated and oxidized). In the fibrous MWCNT, cell growth suppression, as well as expression of inflammatory cytokine genes was observed, as in previous reports. In contrast, no significant toxicity was observed for particulate CB and CNHs, which was different from the report of CB cytotoxicity in vascular endothelial cells. These results show that (1) lymph endothelial cells need to be tested separately from other endothelial cells for safety evaluation of nanomaterials, and (2) the potential of CNHs as DDSs. | |||||||||||||||||||||||||||
| 資源タイプ（コンテンツの種類） | ||||||||||||||||||||||||||||
| ISSN | ||||||||||||||||||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||||||||||||||||||
| 収録物識別子 | 2079-4991 | |||||||||||||||||||||||||||
| PubMed | ||||||||||||||||||||||||||||
| 識別子タイプ | PMID | |||||||||||||||||||||||||||
| 関連識別子 | https://pubmed.ncbi.nlm.nih.gov/32674394 | |||||||||||||||||||||||||||
| 関連名称 | 32674394 | |||||||||||||||||||||||||||
| 権利 | ||||||||||||||||||||||||||||
| 権利情報 | © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | |||||||||||||||||||||||||||
| 出版タイプ | ||||||||||||||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||||||||
| WoS | ||||||||||||||||||||||||||||
| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000557531400001 | |||||||||||||||||||||||||||
Share
Cite as
Sano, Mahoko, Izumiya, Makoto, Haniu, Hisao, Ueda, Katsuya, Konishi, Kosuke, Ishida, Haruka, Kuroda, Chika, Uemura, Takeshi, Aoki, Kaoru, Matsuda, Yoshikazu, Saito, Naoto, 2020, Cellular Responses of Human Lymphatic Endothelial Cells to Carbon Nanomaterials: MDPI, 1374– p.
Loading...
