Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2021-02-22 |
タイトル |
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タイトル |
Electron Microscopy Observation of Human Pulmonary Ultrastructure in Two Patients with High-Altitude Pulmonary Edema |
言語 |
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言語 |
eng |
DOI |
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関連識別子 |
https://doi.org/10.1089/ham.2016.0163 |
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関連名称 |
10.1089/ham.2016.0163 |
キーワード |
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主題 |
electron microscopy, high-altitude pulmonary edema, pulmonary alveolar-capillary barrier |
資源タイプ |
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資源 |
http://purl.org/coar/resource_type/c_6501 |
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タイプ |
journal article |
著者 |
Droma, Yunden
Kato, Akane
Ichiyama, Takashi
Kobayashi, Nobumitsu
Honda, Takayuki
Uehara, Takeshi
Hanaoka, Masayuki
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信州大学研究者総覧へのリンク |
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氏名 |
Kato, Akane |
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URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.WmfCyUDm.html |
信州大学研究者総覧へのリンク |
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氏名 |
Ichiyama, Takashi |
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URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.yaDebVym.html |
信州大学研究者総覧へのリンク |
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氏名 |
Honda, Takayuki |
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URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.WeDUHFkh.html |
信州大学研究者総覧へのリンク |
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氏名 |
Uehara, Takeshi |
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URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.jNyegpkh.html |
信州大学研究者総覧へのリンク |
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氏名 |
Hanaoka, Masayuki |
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URL |
https://soar-rd.shinshu-u.ac.jp/profile/ja.yCLmHVkh.html |
出版者 |
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出版者 |
MARY ANN LIEBERT, INC |
引用 |
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内容記述 |
HIGH ALTITUDE MEDICINE & BIOLOGY.18(3):288-291(2017) |
書誌情報 |
HIGH ALTITUDE MEDICINE & BIOLOGY
巻 18,
号 3,
p. 288-291,
発行日 2017-09-01
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抄録 |
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内容記述 |
We examined the pulmonary ultrastructure in tissue from two patients with high-altitude pulmonary edema (HAPE) by electron microscopy. In one case, we found that neutrophils were trapped in pulmonary capillary lumen of alveolar-capillary wall and part of the cytoplasm of a neutrophil protruded and adhered to the capillary endothelium. There were several degranulated vacuoles in the cytoplasm of the neutrophil. The pulmonary capillary wall was deformed, thickened, and swollen and there was evidence of degeneration. In another case, infiltration of neutrophils and macrophages, proliferation of type II pneumocytes, and numerous red blood cells were also observed in alveolar air space. These electron microscopic ultrastructural observations illustrate for the first time damage to the pulmonary alveolar-capillary barrier in lung tissue of humans with advanced HAPE. |
資源タイプ(コンテンツの種類) |
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内容記述 |
Article |
ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
1527-0297 |
書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA11647643 |
PubMed |
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関連識別子 |
https://www.ncbi.nlm.nih.gov/pubmed/28876136 |
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関連名称 |
28876136 |
権利 |
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権利情報 |
This is the accepted version of the following article: Electron Microscopy Observation of Human Pulmonary Ultrastructure in Two Patients with High-Altitude Pulmonary Edema. Yunden Droma, Akane Kato, Takashi Ichiyama, Nobumitsu Kobayashi, Takayuki Honda, Takeshi Uehara, and Masayuki Hanaoka. High Altitude Medicine & Biology 2017 18:3, 288-291, which has now been formally published in final form at High Altitude Medicine & Biology at https://doi.org/10.1089/ham.2016.0163. This original submission version of the article may be used for non-commercial purposes in accordance with the Mary Ann Liebert, Inc., publishers’ self-archiving terms and conditions. |
出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
WoS |
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URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000410924100013 |