Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2011-11-14 |
タイトル |
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タイトル |
Toxicoproteomic evaluation of carbon nanomaterials in vitro |
言語 |
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言語 |
eng |
DOI |
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関連識別子 |
https://doi.org/10.1016/j.jprot.2011.03.004 |
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関連名称 |
10.1016/j.jprot.2011.03.004 |
キーワード |
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主題 |
Toxicoproteomics, Chronic toxicity, Carbon nanotubes, Nanomaterials, in vitro |
資源タイプ |
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資源 |
http://purl.org/coar/resource_type/c_6501 |
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タイプ |
journal article |
著者 |
Haniu, Hisao
Matsuda, Yoshikazu
Usui, Yuki
Aoki, Kaoru
Shimizu, Masayuki
Ogihara, Nobuhide
Hara, Kazuo
Okamoto, Masanori
Takanashi, Seiji
Ishigaki, Norio
Nakamura, Koichi
Kato, Hiroyuki
Saito, Naoto
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信州大学研究者総覧へのリンク |
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氏名 |
Haniu, Hisao |
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URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.jakpPmSa.html |
信州大学研究者総覧へのリンク |
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氏名 |
Kato, Hiroyuki |
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URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.WVkCbaSp.html |
信州大学研究者総覧へのリンク |
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氏名 |
Saito, Naoto |
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URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.WpkhuUkh.html |
出版者 |
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出版者 |
Elsevier B.V. |
引用 |
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内容記述 |
Journal of Proteomics. 74(12):2703-2712 (2011) |
書誌情報 |
Journal of Proteomics
巻 18,
号 12,
p. 2703-2712,
発行日 2011-11-18
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抄録 |
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内容記述 |
Carbon nanotubes (CNTs) have already been successfully implemented in various fields, and they are anticipated to have innovative applications in medical science. However, CNTs have asbestos-like properties, such as their nanoscale size and high aspect ratio (> 100). Moreover, CNTs may persist in the body for a long time. These properties are thought to cause malignant mesothelioma and lung cancer. However, based on conventional toxicity assessment systems, the carcinogenicity of asbestos and CNTs is unclear. The reason for late countermeasures against asbestos is that reliable, long-term safety assessments have not yet been developed by toxicologists. Therefore, a new type of long-term safety assessment, different from the existing methods, is needed for carbon nanomaterials. Recently, we applied a proteomic approach to the safety assessment of carbon nanomaterials. In this review, we discuss the basic concept of our approach, the results, the problems, and the possibility of a long-term safety assessment for carbon nanomaterials using the toxicoproteomic approach. |
資源タイプ(コンテンツの種類) |
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内容記述 |
Article |
ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
1874-3919 |
書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA11685085 |
PubMed |
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関連識別子 |
https://pubmed.ncbi.nlm.nih.gov/21406258/ |
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関連名称 |
21406258 |
権利 |
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権利情報 |
Copyright © 2011 Elsevier B.V. |
出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
WoS |
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URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000298305900012 |