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Methods Imaging and histologic finding of the bile duct were assessed for 73 patients with autoimmune pancreatitis to clarify whether IgG4-related biliary inflammation or pancreatic head swelling is associated with lower bile duct stricture. Results Lower bile duct stricture was found in 59 (81%) patients. Pancreatic head swelling was significantly more frequent among patients with lower bile duct stricture than those patients without lower bile duct stricture (53 [90%] vs 4 [29%]; P \u003c 0.01). Intraductal ultrasonography findings revealed lower bile duct wall thickening in 21 (95%) of the 22 patients with lower bile duct stricture, and the lower bile duct wall of the patients with pancreatic head swelling was significantly thicker than those patients without pancreatic head swelling (P = 0.028). Among the 38 patients with lower bile duct biopsies, 14 (37%) exhibited abundant IgG4-bearing plasma cell infiltration. 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  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

Mechanisms of Lower Bile Duct Stricture in Autoimmune Pancreatitis

http://hdl.handle.net/10091/17845
ca4a5588-5d98-4cf3-a6da-1e812b2702e6
名前 / ファイル ライセンス アクション
Mechanisms_Lower_Bile_Duct_Stricture.pdf Mechanisms_Lower_Bile_Duct_Stricture.pdf (419.0 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-09-05
タイトル
言語 en
タイトル Mechanisms of Lower Bile Duct Stricture in Autoimmune Pancreatitis
言語
言語 eng
キーワード
主題Scheme Other
主題 autoimmune pancreatitis
キーワード
主題Scheme Other
主題 IgG4
キーワード
主題Scheme Other
主題 IgG4-related sclerosing cholangitis
キーワード
主題Scheme Other
主題 IgG4-related disease
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Watanabe, Takayuki

× Watanabe, Takayuki

WEKO 6239

en Watanabe, Takayuki

Search repository
Maruyama, Masahiro

× Maruyama, Masahiro

WEKO 6240

en Maruyama, Masahiro

Search repository
Ito, Tetsuya

× Ito, Tetsuya

WEKO 6241

en Ito, Tetsuya

Search repository
Maruyama, Masafumi

× Maruyama, Masafumi

WEKO 6242

en Maruyama, Masafumi

Search repository
Muraki, Takashi

× Muraki, Takashi

WEKO 6243

en Muraki, Takashi

Search repository
Hamano, Hideaki

× Hamano, Hideaki

WEKO 6244

en Hamano, Hideaki

Search repository
Arakura, Norikazu

× Arakura, Norikazu

WEKO 6245

en Arakura, Norikazu

Search repository
Hasebe, Osamu

× Hasebe, Osamu

WEKO 6246

en Hasebe, Osamu

Search repository
Kawa, Shigeyuki

× Kawa, Shigeyuki

WEKO 6247

en Kawa, Shigeyuki

Search repository
信州大学研究者総覧へのリンク
氏名 Kawa, Shigeyuki
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.jakeOVkh.html
出版者
出版者 LIPPINCOTT WILLIAMS & WILKINS
引用
内容記述タイプ Other
内容記述 PANCREAS. 43(2):255-260 (2014)
書誌情報 PANCREAS

巻 43, 号 2, p. 255-260, 発行日 2014-03
抄録
内容記述タイプ Abstract
内容記述 Objectives We attempted to clarify the mechanism underlying lower bile duct stricture in autoimmune pancreatitis. Methods Imaging and histologic finding of the bile duct were assessed for 73 patients with autoimmune pancreatitis to clarify whether IgG4-related biliary inflammation or pancreatic head swelling is associated with lower bile duct stricture. Results Lower bile duct stricture was found in 59 (81%) patients. Pancreatic head swelling was significantly more frequent among patients with lower bile duct stricture than those patients without lower bile duct stricture (53 [90%] vs 4 [29%]; P < 0.01). Intraductal ultrasonography findings revealed lower bile duct wall thickening in 21 (95%) of the 22 patients with lower bile duct stricture, and the lower bile duct wall of the patients with pancreatic head swelling was significantly thicker than those patients without pancreatic head swelling (P = 0.028). Among the 38 patients with lower bile duct biopsies, 14 (37%) exhibited abundant IgG4-bearing plasma cell infiltration. Among the patients with lower bile duct stricture, an IgG4-related inflammation seemed to exert a dominant effect under limited conditions, including concomitant middle bile duct stricture and neither pancreatic swelling nor pancreatic duct stricture in the head region. Conclusions Both pancreatic head swelling and IgG4-related biliary inflammation affect lower bile duct stricture, which may be included in IgG4-related sclerosing cholangitis. Pancreatic head swelling affects IgG4-related biliary wall thickening.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 0885-3177
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA10674276
PubMed
関連識別子
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/24518505
関連名称
関連名称 24518505
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1097/01.mpa.0000437323.52598.20
関連名称
関連名称 10.1097/01.mpa.0000437323.52598.20
権利
権利情報 Copyright© 2014 Lippincott Williams and Wilkins / This is a non-final version of an article published in final form in PANCREAS. 43(2):255-260 (2014)
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000331556300013
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