{"_buckets": {"deposit": "27826b39-dedf-4d43-8568-5b174806a5dc"}, "_deposit": {"id": "3677", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "3677"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00003677", "sets": ["462"]}, "author_link": ["6251", "6252", "6253", "6254", "6255", "6256", "6257"], "item_1628147817048": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_6_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2014-04-15", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "41641", "bibliographicPageEnd": "234", "bibliographicPageStart": "231", "bibliographicVolumeNumber": "339", "bibliographic_titles": [{"bibliographic_title": "JOURNAL OF THE NEUROLOGICAL SCIENCES"}]}]}, "item_6_description_20": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "A 63-year-old woman with a past history of right subdural hematoma (SDH) at the age of 61 years was referred to our hospital under a suspicion of aceruloplasminemia (ACP). A neurological examination revealed very mild cognitive impairment and cerebellar ataxia. Blood chemistry data showed deficient ceruloplasmin (Cp), decreased copper, and increased ferritin. A nonsense mutation (c.2630G \u003e A, p.Trp858Ter) was detected in the Cp gene. Brain magnetic resonance imaging (MRI) showed marked hypointensity at the surface of the cerebrum, cerebellum, and brainstem bilaterally, in addition to the bilateral basal ganglia, thalamus, and dentate nucleus, suggesting the coexistence of ACP and superficial siderosis (SS). The characteristics of SS in ACP have not been examined neuroradiologically or neuropathologically in great detail, while SDH and its curative surgery are known to cause SS. The distribution of the hypointensity areas on MRI was expanded bilaterally to the subtentorial areas of this patient, which was much more widespread than observed in typical SS after SDH. We speculate that the underlying ACP may expand the SS induced by SDH. Cp would accelerate iron export from the brain via the blood-cerebrospinal fluid (CSF) barrier, or CSF-brain barrier when excessive iron is loaded into the subarachnoid space.", "subitem_description_type": "Abstract"}]}, "item_6_description_30": {"attribute_name": "資源タイプ（コンテンツの種類）", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "JOURNAL OF THE NEUROLOGICAL SCIENCES. 339(41641):231-234 (2014)", "subitem_description_type": "Other"}]}, "item_6_link_3": {"attribute_name": "信州大学研究者総覧へのリンク", "attribute_value_mlt": [{"subitem_link_text": "Yoshida, Kunihiro", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.yhfNHFkh.html"}]}, "item_6_link_67": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000335123500046"}]}, "item_6_publisher_4": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "ELSEVIER SCIENCE BV"}]}, "item_6_relation_47": {"attribute_name": "PubMed", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "24607334"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://pubmed.ncbi.nlm.nih.gov/24607334", "subitem_relation_type_select": "PMID"}}]}, "item_6_relation_48": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1016/j.jns.2014.02.014"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1016/j.jns.2014.02.014", "subitem_relation_type_select": "DOI"}}]}, "item_6_rights_62": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright© 2014 Elsevier B.V."}]}, "item_6_select_64": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_6_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0022-510X", "subitem_source_identifier_type": "PISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0022-510X", "subitem_source_identifier_type": "PISSN"}]}, "item_6_source_id_40": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00703265", "subitem_source_identifier_type": "NCID"}]}, "item_6_text_69": {"attribute_name": "wosonly authkey", "attribute_value_mlt": [{"subitem_text_value": "Aceruloplasminemia; Superficial siderosis; Blood-cerebrospinal fluid (CSF) barrier; CSF-brain barrier; Ceruloplasmin; Macrophage"}]}, "item_6_text_70": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "CENTRAL-NERVOUS-SYSTEM; CERULOPLASMIN GENE; BRAIN IRON; EXPRESSION; PATHOLOGY; COPPER"}]}, "item_6_textarea_68": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "A 63-year-old woman with a past history of right subdural hematoma (SDH) at the age of 61 years was referred to our hospital under a suspicion of aceruloplasminemia (ACP). A neurological examination revealed very mild cognitive impairment and cerebellar ataxia. Blood chemistry data showed deficient ceruloplasmin (Cp), decreased copper, and increased ferritin. A nonsense mutation (c.2630G \u003e A, p.Trp858Ter) was detected in the Cp gene. Brain magnetic resonance imaging (MRI) showed marked hypointensity at the surface of the cerebrum, cerebellum, and brainstem bilaterally, in addition to the bilateral basal ganglia, thalamus, and dentate nucleus, suggesting the coexistence of ACP and superficial siderosis (SS). The characteristics of SS in ACP have not been examined neuroradiologically or neuropathologically in great detail, while SDH and its curative surgery are known to cause SS. The distribution of the hypointensity areas on MRI was expanded bilaterally to the subtentorial areas of this patient, which was much more widespread than observed in typical SS after SDH. We speculate that the underlying ACP may expand the SS induced by SDH. Cp would accelerate iron export from the brain via the blood-cerebrospinal fluid (CSF) barrier, or CSF-brain barrier when excessive iron is loaded into the subarachnoid space. ? 2014 Elsevier B.V. All rights reserved."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Matsushima,  Akira", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6251", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshida,  Toshikazu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6252", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshida,  Kunihiro", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6253", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ohara,  Shinji", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6254", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Toyoshima,  Yasuko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6255", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kakita,  Akiyoshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6256", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ikeda,  Shu-ichi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6257", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Superficial_siderosis_associated_aceruloplasminemia.pdf", "filesize": [{"value": "423.6 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 423600.0, "url": {"label": "Superficial_siderosis_associated_aceruloplasminemia.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/3677/files/Superficial_siderosis_associated_aceruloplasminemia.pdf"}, "version_id": "f5c1182c-f3e3-4d33-871c-ab9b2fcbf0fb"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Aceruloplasminemia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Superficial siderosis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Blood-cerebrospinal fluid (CSF) barrier", "subitem_subject_scheme": "Other"}, {"subitem_subject": "CSF-brain barrier", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Ceruloplasmin", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Macrophage", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Superficial siderosis associated with aceruloplasminemia. 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