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  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

Superficial siderosis associated with aceruloplasminemia. Case report

http://hdl.handle.net/10091/17832
http://hdl.handle.net/10091/17832
7636be17-382f-4d7c-bb6d-83e0fe53d93c
名前 / ファイル ライセンス アクション
Superficial_siderosis_associated_aceruloplasminemia.pdf Superficial_siderosis_associated_aceruloplasminemia.pdf (423.6 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-09-05
タイトル
言語 en
タイトル Superficial siderosis associated with aceruloplasminemia. Case report
言語
言語 eng
キーワード
主題Scheme Other
主題 Aceruloplasminemia
キーワード
主題Scheme Other
主題 Superficial siderosis
キーワード
主題Scheme Other
主題 Blood-cerebrospinal fluid (CSF) barrier
キーワード
主題Scheme Other
主題 CSF-brain barrier
キーワード
主題Scheme Other
主題 Ceruloplasmin
キーワード
主題Scheme Other
主題 Macrophage
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Matsushima, Akira

× Matsushima, Akira

WEKO 6251

en Matsushima, Akira

Search repository
Yoshida, Toshikazu

× Yoshida, Toshikazu

WEKO 6252

en Yoshida, Toshikazu

Search repository
Yoshida, Kunihiro

× Yoshida, Kunihiro

WEKO 6253

en Yoshida, Kunihiro

Search repository
Ohara, Shinji

× Ohara, Shinji

WEKO 6254

en Ohara, Shinji

Search repository
Toyoshima, Yasuko

× Toyoshima, Yasuko

WEKO 6255

en Toyoshima, Yasuko

Search repository
Kakita, Akiyoshi

× Kakita, Akiyoshi

WEKO 6256

en Kakita, Akiyoshi

Search repository
Ikeda, Shu-ichi

× Ikeda, Shu-ichi

WEKO 6257

en Ikeda, Shu-ichi

Search repository
信州大学研究者総覧へのリンク
氏名 Yoshida, Kunihiro
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.yhfNHFkh.html
出版者
出版者 ELSEVIER SCIENCE BV
引用
内容記述タイプ Other
内容記述 JOURNAL OF THE NEUROLOGICAL SCIENCES. 339(41641):231-234 (2014)
書誌情報 JOURNAL OF THE NEUROLOGICAL SCIENCES

巻 339, 号 41641, p. 231-234, 発行日 2014-04-15
抄録
内容記述タイプ Abstract
内容記述 A 63-year-old woman with a past history of right subdural hematoma (SDH) at the age of 61 years was referred to our hospital under a suspicion of aceruloplasminemia (ACP). A neurological examination revealed very mild cognitive impairment and cerebellar ataxia. Blood chemistry data showed deficient ceruloplasmin (Cp), decreased copper, and increased ferritin. A nonsense mutation (c.2630G > A, p.Trp858Ter) was detected in the Cp gene. Brain magnetic resonance imaging (MRI) showed marked hypointensity at the surface of the cerebrum, cerebellum, and brainstem bilaterally, in addition to the bilateral basal ganglia, thalamus, and dentate nucleus, suggesting the coexistence of ACP and superficial siderosis (SS). The characteristics of SS in ACP have not been examined neuroradiologically or neuropathologically in great detail, while SDH and its curative surgery are known to cause SS. The distribution of the hypointensity areas on MRI was expanded bilaterally to the subtentorial areas of this patient, which was much more widespread than observed in typical SS after SDH. We speculate that the underlying ACP may expand the SS induced by SDH. Cp would accelerate iron export from the brain via the blood-cerebrospinal fluid (CSF) barrier, or CSF-brain barrier when excessive iron is loaded into the subarachnoid space.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 0022-510X
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00703265
PubMed
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/24607334
関連名称 24607334
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.jns.2014.02.014
関連名称 10.1016/j.jns.2014.02.014
権利
権利情報 Copyright© 2014 Elsevier B.V.
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000335123500046
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