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Different cortical metabolic activation by visual stimuli possibly due to different time courses of hearing loss in patients with GJB2 and SLC26A4 mutations
http://hdl.handle.net/10091/17785
http://hdl.handle.net/10091/177855a6ece30-f143-4792-9421-a8480faf0d4e
| 名前 / ファイル | ライセンス | アクション |
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Different_cortical_metabolic_activation.pdf (315.2 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||||
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| 公開日 | 2014-07-25 | |||||||||||||||||||||
| タイトル | ||||||||||||||||||||||
| タイトル | Different cortical metabolic activation by visual stimuli possibly due to different time courses of hearing loss in patients with GJB2 and SLC26A4 mutations | |||||||||||||||||||||
| 言語 | ||||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||||
| DOI | ||||||||||||||||||||||
| 関連識別子 | https://doi.org/10.3109/00016489.2011.593719 | |||||||||||||||||||||
| 関連名称 | 10.3109/00016489.2011.593719 | |||||||||||||||||||||
| キーワード | ||||||||||||||||||||||
| 主題 | FDG-PET, visual language task, functional brain imaging | |||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||
| タイプ | journal article | |||||||||||||||||||||
| 著者 |
Moteki, Hideaki
× Moteki, Hideaki
× Naito, Yasushi
× Fujiwara, Keizo
× Kitoh, Ryosuke
× Nishio, Shin-ya
× Oguchi, Kazuhiro
× Takumi, Yutaka
× Usami, Shin-ichi
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| 信州大学研究者総覧へのリンク | ||||||||||||||||||||||
| 氏名 | Moteki, Hideaki | |||||||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.HNcauNkh.html | |||||||||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||||||||
| 氏名 | Kitoh, Ryosuke | |||||||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.uakCgpkh.html | |||||||||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||||||||
| 氏名 | Nishio, Shin-ya | |||||||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.uCSmPpym.html | |||||||||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||||||||
| 氏名 | Takumi, Yutaka | |||||||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.HNnNHhSC.html | |||||||||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||||||||
| 氏名 | Usami, Shin-ichi | |||||||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.ZmAUHUSC.html | |||||||||||||||||||||
| 出版者 | ||||||||||||||||||||||
| 出版者 | INFORMA HEALTHCARE | |||||||||||||||||||||
| 引用 | ||||||||||||||||||||||
| 内容記述 | ACTA OTO-LARYNGOLOGICA. 131(11):1232-1236 (2011) | |||||||||||||||||||||
| 書誌情報 |
ACTA OTO-LARYNGOLOGICA 巻 131, 号 11, p. 1232-1236, 発行日 2011-11 |
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| 抄録 | ||||||||||||||||||||||
| 内容記述 | Conclusion. We have demonstrated differences in cortical activation with language-related visual stimuli in patients who were profoundly deafened due to genetic mutations in GJB2 and SLC26A4. The differences in cortical processing patterns between these two cases may have been influenced by the differing clinical courses and pathogenesis of hearing loss due to genetic mutations. Our results suggest the importance of hearing during early childhood for the development of a normal cortical language network. Objectives. To investigate the cortical activation with language-related visual stimuli in patients who were profoundly deafened due to genetic mutations in GJB2 and SLC26A4. Methods: The cortical activity of two adult patients with known genetic mutations (GJB2, SLC26A4) was evaluated with fluorodeoxyglucose-positron emission tomography (FDG-PET) with a visual language task and compared with that of normal-hearing controls. Results: A patient with a GJB2 mutation showed activation in the right auditory association area [BA21, BA22], and the left auditory association area [BA42] even with visual language task; in contrast, a patient with an SLC26A4 mutation showed no significant activation in the corresponding area. | |||||||||||||||||||||
| 資源タイプ（コンテンツの種類） | ||||||||||||||||||||||
| ISSN | ||||||||||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||||||||||
| 収録物識別子 | 0001-6489 | |||||||||||||||||||||
| 書誌レコードID | ||||||||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||||||||
| 収録物識別子 | AA0050923X | |||||||||||||||||||||
| PubMed | ||||||||||||||||||||||
| 識別子タイプ | PMID | |||||||||||||||||||||
| 関連識別子 | https://pubmed.ncbi.nlm.nih.gov/21728752 | |||||||||||||||||||||
| 関連名称 | 21728752 | |||||||||||||||||||||
| 権利 | ||||||||||||||||||||||
| 権利情報 | Copyright© 2011 Informa Healthcare | |||||||||||||||||||||
| 出版タイプ | ||||||||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||
| WoS | ||||||||||||||||||||||
| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000295581800017 | |||||||||||||||||||||
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Cite as
Moteki, Hideaki, Naito, Yasushi, Fujiwara, Keizo, Kitoh, Ryosuke, Nishio, Shin-ya, Oguchi, Kazuhiro, Takumi, Yutaka, Usami, Shin-ichi, 2011, Different cortical metabolic activation by visual stimuli possibly due to different time courses of hearing loss in patients with GJB2 and SLC26A4 mutations: INFORMA HEALTHCARE, 1232–1236 p.
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