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More severe impairment of manual dexterity in bipolar disorder compared to unipolar major depression
http://hdl.handle.net/10091/17720
http://hdl.handle.net/10091/177201b5a3ca3-5401-4143-b744-50367119701b
| 名前 / ファイル | ライセンス | アクション |
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More_severe_impairment_manual_dexterity.pdf (240.7 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2014-07-23 | |||||
| タイトル | ||||||
| タイトル | More severe impairment of manual dexterity in bipolar disorder compared to unipolar major depression | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| DOI | ||||||
| 関連名称 | 10.1016/j.jad.2011.11.031 | |||||
| キーワード | ||||||
| 主題 | Unipolar depression, Bipolar disorder, Dexterity, Lithium, Antipsychotics | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Sasayama, Daimei
× Sasayama, Daimei× Hori, Hiroaki× Teraishi, Toshiya× Hattori, Kotaro× Ota, Miho× Matsuo, Junko× Kawamoto, Yumiko× Kinoshita, Yukiko× Hashikura, Miyako× Amano, Naoji× Higuchi, Teruhiko× Kunugi, Hiroshi |
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| 信州大学研究者総覧へのリンク | ||||||
| 表示名 | Sasayama, Daimei | |||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.uNkegpkh.html | |||||
| 出版者 | ||||||
| 出版者 | ELSEVIER SCIENCE BV | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | JOURNAL OF AFFECTIVE DISORDERS. 136(3):1047-1052 (2012) | |||||
| 書誌情報 |
JOURNAL OF AFFECTIVE DISORDERS 巻 136, 号 3, p. 1047-1052, 発行日 2012-02 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background: Mood disorders are associated with various neurocognitive deficits. However, few studies have reported the impairment of motor dexterity in unipolar depression and bipolar disorder. In the present study, manual dexterity was compared between unipolar major depression, bipolar disorder, and healthy controls. Methods: Manual dexterity was assessed by the Purdue pegboard test in 98 patients with unipolar major depression, 48 euthymic or depressed patients with bipolar disorder, and 158 healthy controls, matched for age and gender. Results: Compared to healthy controls, sum of the scores of right, left, and both hands subtests (R + L+ B) was significantly lower in both patients with unipolar depression and bipolar disorder (P= 0.0034 and P<0.0001, respectively). Furthermore, R + L + B was significantly lower in bipolar disorder compared to unipolar depression (P=0.0016). Lithium dose and chlorpromazine equivalent dose of antipsychotics were significantly negatively correlated with some of the subtest scores. On the other hand, depression severity did not significantly correlate with any of the subtest scores. Difference in R + L+ B between unipolar depression and bipolar disorder remained statistically significant even after controlling for gender, age, lithium dose, and chlorpromazine equivalent dose (P = 0.0028). Limitations Bipolar patients during manic episode were not included in the study. Conclusions: Gross movement dexterity was impaired in both patients with unipolar depression and bipolar disorder. The severity of impairment was significantly greater in patients with bipolar disorder. The functional difference between unipolar and bipolar patients may suggest different pathological conditions between the two depressive disorders. | |||||
| 資源タイプ（コンテンツの種類） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Article | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0165-0327 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00256633 | |||||
| PubMed | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | https://pubmed.ncbi.nlm.nih.gov/22169250 | |||||
| 関連名称 | 22169250 | |||||
| 権利 | ||||||
| 権利情報 | Copyright© 2011 Elsevier | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| WoS | ||||||
| 表示名 | Web of Science | |||||
| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000301996000114 | |||||
