Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2014-06-17 |
タイトル |
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タイトル |
Transmission of Systemic AA Amyloidosis in Animals |
言語 |
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言語 |
eng |
DOI |
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関連識別子 |
https://doi.org/10.1177/0300985813511128 |
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関連名称 |
10.1177/0300985813511128 |
キーワード |
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主題 |
prion-like transmission, cheetah, amyloid-enhancing factor, serum amyloid A, mouse, AA amyloidosis, bird, cattle |
資源タイプ |
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資源 |
http://purl.org/coar/resource_type/c_6501 |
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タイプ |
journal article |
著者 |
Murakami, T
Ishiguro, N
Higuchi, K
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信州大学研究者総覧へのリンク |
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氏名 |
Higuchi, K |
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URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.gCfUPmAh.html |
出版者 |
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出版者 |
SAGE PUBLICATIONS INC |
引用 |
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内容記述 |
VETERINARY PATHOLOGY. 51(2):363-371 (2014) |
書誌情報 |
VETERINARY PATHOLOGY
巻 51,
号 2,
p. 363-371,
発行日 2014-03
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抄録 |
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内容記述 |
Amyloidoses are a group of protein-misfolding disorders that are characterized by the deposition of amyloid fibrils in organs and/or tissues. In reactive amyloid A (AA) amyloidosis, serum AA (SAA) protein forms deposits in mice, domestic and wild animals, and humans that experience chronic inflammation. AA amyloid fibrils are abnormal beta-sheet-rich forms of the serum precursor SAA, with conformational changes that promote fibril formation. Extracellular deposition of amyloid fibrils causes disease in affected animals. Recent findings suggest that AA amyloidosis could be transmissible. Similar to the pathogenesis of transmissible prion diseases, amyloid fibrils induce a seeding-nucleation process that may lead to development of AA amyloidosis. We review studies of possible transmission in bovine, avian, mouse, and cheetah AA amyloidosis. |
資源タイプ(コンテンツの種類) |
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内容記述 |
Article |
ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0300-9858 |
書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA00883666 |
PubMed |
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関連識別子 |
https://pubmed.ncbi.nlm.nih.gov/24280941 |
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関連名称 |
24280941 |
権利 |
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権利情報 |
The final, definitive version of this paper has been published in Veterinary Pathology, vol. 51 no. 2, March 2014 by SAGE Publications Ltd, All rights reserved. Copyright© 2014 American College of Veterinary Pathologists |
出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
WoS |
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URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000332610500006 |