Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2014-06-05 |
タイトル |
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タイトル |
Myocardial Performance Index in Subjects Susceptible to High-Altitude Pulmonary Edema |
言語 |
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言語 |
eng |
DOI |
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関連識別子 |
https://doi.org/10.2169/internalmedicine.50.5942 |
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関連名称 |
10.2169/internalmedicine.50.5942 |
キーワード |
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主題 |
Doppler examination, hypoxia, myocardial performance, pulmonary hypertension, Tei index |
資源タイプ |
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資源 |
http://purl.org/coar/resource_type/c_6501 |
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タイプ |
journal article |
著者 |
Hanaoka, Masayuki
Kogashi, Kaoru
Droma, Yunden
Urushihata, Kazuhisa
Kubo, Keishi
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信州大学研究者総覧へのリンク |
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氏名 |
Hanaoka, Masayuki |
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URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.yCLmHVkh.html |
信州大学研究者総覧へのリンク |
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氏名 |
Urushihata, Kazuhisa |
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URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.jakhHVkh.html |
出版者 |
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出版者 |
JAPAN SOC INTERNAL MEDICINE |
引用 |
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内容記述 |
INTERNAL MEDICINE. 50(24):2967-2973 (2011) |
書誌情報 |
INTERNAL MEDICINE
巻 50,
号 24,
p. 2967-2973,
発行日 2011
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抄録 |
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内容記述 |
Objective A recent study concerning high-altitude pulmonary edema (HAPE), a non-cardiogenic pulmonary edema, suggested that it is initially a hydrostatic-type pulmonary edema. We suspect that some extent of cardiac insufficiency may likely relate to the mechanism of the development of this disease. Methods By Doppler echocardiography, the Tei index (a new quantitative index proposed for the evaluation of global myocardial performance) and the systolic pulmonary artery pressure (sPAP) were measured before and after 30 minutes of hypoxic breathing. Patients Eleven HAPE-susceptible subjects (HAPE-s) and nine HAPE-resistant subjects (HAPE-r). Results The results of Tei index indicated an enhanced left myocardial performance but an impaired right performance in HAPE-s during hypoxic breathing. The sPAP of HAPE-s was significantly increased after hypoxic breathing, which was not correlated with the heart functions such as right ventricular (RV) Tei index, cardiac index (CI), percent ejection fraction (EF%) and percent fractional shortening (FS%) under hypoxic condition. Comparatively, the HAPE-r subjects did not show such significant changes of Tei index after hypoxic breathing. The results suggested that a paradoxical myocardial performance, in a format of an augmented left ventricular (LV) in contrast to an attenuated RV, was observed in the HAPE-s exposed to acute hypoxia. Conclusion The responses of the left and right myocardial performances to hypoxia may be involved in the pathogenesis of HAPE. |
資源タイプ(コンテンツの種類) |
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内容記述 |
Article |
ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0918-2918 |
書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA10827774 |
PubMed |
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関連識別子 |
https://pubmed.ncbi.nlm.nih.gov/22185987 |
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関連名称 |
22185987 |
権利 |
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権利情報 |
Copyright© 2011 The Japanese Society of Internal Medicine |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
WoS |
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URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000299379200007 |