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  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

Clinical effects of stereotactic radiation surgery in patients with metastatic melanoma

http://hdl.handle.net/10091/17338
516da756-448f-4228-877e-c84addcb1e1d
名前 / ファイル ライセンス アクション
Clinical_effects_stereotactic_radiation_surgery.pdf Clinical_effects_stereotactic_radiation_surgery.pdf (228.8 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-01-21
タイトル
言語 en
タイトル Clinical effects of stereotactic radiation surgery in patients with metastatic melanoma
言語
言語 eng
キーワード
主題Scheme Other
主題 disease-free survival
キーワード
主題Scheme Other
主題 gamma knife
キーワード
主題Scheme Other
主題 melanoma
キーワード
主題Scheme Other
主題 overall survival
キーワード
主題Scheme Other
主題 stereotactic radiation surgery
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Mikoshiba, Asuka

× Mikoshiba, Asuka

WEKO 6917

en Mikoshiba, Asuka

Search repository
Uhara, Hisashi

× Uhara, Hisashi

WEKO 6918

en Uhara, Hisashi

Search repository
Murata, Hiroshi

× Murata, Hiroshi

WEKO 6919

en Murata, Hiroshi

Search repository
Okuyama, Ryuhei

× Okuyama, Ryuhei

WEKO 6920

en Okuyama, Ryuhei

Search repository
信州大学研究者総覧へのリンク
氏名 Okuyama, Ryuhei
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.ZpfNHFSF.html
出版者
出版者 WILEY-BLACKWELL
引用
内容記述タイプ Other
内容記述 JOURNAL OF DERMATOLOGY. 40(8):626-628 (2013)
書誌情報 JOURNAL OF DERMATOLOGY

巻 40, 号 8, p. 626-628, 発行日 2013-08
抄録
内容記述タイプ Abstract
内容記述 We examined the effectiveness of stereotactic radiation surgery (SRS) in 14 patients with brain metastasis in our hospital. The age of the patients ranged 45-85 years old (mean, 65). Brain metastasis was detected by neurological symptoms in seven patients and by regular imaging examination in the remaining patients. The number of metastatic lesions in the brain before SRS ranged 1-11 (median, 2). The treatment number of SRS was 1-4 times (median, 2). Six of 14 patients had neurological symptoms before SRS. Overall survival (OS) after SRS was 1.721.2 months (median, 8.2). The progression-free survival (PFS) after SRS was 0.9-10.5 months (median, 2.2). The result of univariate analysis showed that the application of two or more courses of SRS was significantly related to OS (P = 0.005). Single metastatic lesion (P = 0.051) and no extracranial lesion (P = 0.055) showed a slight tendency to be related to disease-free survival (DFS). Neither lactate dehydrogenase nor neurological symptoms were significantly related to OS or DFS. Although OS and DFS after SRS were not very long, the treatment of brain metastases has the potential to prevent neurological events. Repeating SRS may be accepted as a local therapy in the multimodal approach including new molecular targeting drugs for metastatic melanoma.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 0385-2407
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00696658
PubMed
関連識別子
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/23682870
関連名称
関連名称 23682870
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1111/1346-8138.12179
関連名称
関連名称 10.1111/1346-8138.12179
権利
権利情報 Copyright© 2013 Japanese Dermatological Association
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000326243600005
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