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  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

Platinum and anthracycline therapy for advanced cutaneous squamous cell carcinoma

http://hdl.handle.net/10091/17337
http://hdl.handle.net/10091/17337
99cbc4e4-f56c-4b82-8b79-e330fdc97069
名前 / ファイル ライセンス アクション
Platinum_anthracycline_therapy_advanced_cutaneous_squamous.pdf Platinum_anthracycline_therapy_advanced_cutaneous_squamous.pdf (177.4 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-01-21
タイトル
タイトル Platinum and anthracycline therapy for advanced cutaneous squamous cell carcinoma
言語
言語 eng
DOI
関連識別子 https://doi.org/10.1007/s10147-012-0411-y
関連名称 10.1007/s10147-012-0411-y
キーワード
主題 Chemotherapy, Cutaneous squamous cell carcinoma, Skin cancer, Platinum, Anthracycline
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Nakamura, Kenta

× Nakamura, Kenta

en Nakamura, Kenta

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Okuyama, Ryuhei

× Okuyama, Ryuhei

en Okuyama, Ryuhei

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Saida, Toshiaki

× Saida, Toshiaki

en Saida, Toshiaki

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Uhara, Hisashi

× Uhara, Hisashi

en Uhara, Hisashi

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信州大学研究者総覧へのリンク
氏名 Okuyama, Ryuhei
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.ZpfNHFSF.html
出版者
出版者 SPRINGER JAPAN KK
引用
内容記述 INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY. 18(3):506-509 (2013)
書誌情報 INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY

巻 18, 号 3, p. 506-509, 発行日 2013-06
抄録
内容記述 Because metastatic cutaneous squamous cell carcinoma (CSCC) is rare, standard chemotherapy has not been fully established. In Japan, combination platinum and anthracycline chemotherapy has been used for elderly patients with advanced CSCC because of its low toxicity. However, the clinical benefit of this therapy has not been fully examined. We retrospectively examined the response rate of combination platinum and anthracycline chemotherapy for metastatic CSCC. Eight patients received combination chemotherapy for metastatic lesions; there were lymph node lesions in 6 patients and skin and lung lesions in one patient each. The combination regimens were as follows: cisplatin (CDDP) (60-90 mg/m(2)/day, day 1) and adriamycin (ADM) (20-40 mg/m(2)/day, day 1 or 2) was administered in 5 patients; CDDP (10-15 mg/m(2)/day, days 1-5) and epirubicin (epi-ADM) (10-15 mg/m(2)/day, days 1-5) was administered in 2 patients; and carboplatin (CBDCA) (200-400 mg/m(2)/day, day 1) and ADM (20-40 mg/m(2)/day, day 1 or 2) was administered in one patient. The responses were as follows: complete response in 2 patients (CDDP + ADM for lung metastasis, CDDP + epi-ADM for lymph node metastasis), partial response in 1 (CDDP + ADM for lymph node metastasis), stable disease in 2, and progressive disease in 3. A durable response was observed in 2 patients showing complete responses (58 and 112 months). The clinical effect of the combination of platinum and anthracycline for metastatic CSCC was limited despite the findings of two patients showing durable complete responses.
資源タイプ(コンテンツの種類)
ISSN
収録物識別子タイプ PISSN
収録物識別子 1341-9625
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA11086579
PubMed
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/22534799
関連名称 22534799
権利
権利情報 The original publication is available at www.springerlink.com
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000320456500022
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Cite as

Nakamura, Kenta, Okuyama, Ryuhei, Saida, Toshiaki, Uhara, Hisashi, 2013, Platinum and anthracycline therapy for advanced cutaneous squamous cell carcinoma: SPRINGER JAPAN KK, 506–509 p.

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