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  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

Male lower urinary tract symptoms and a1D-adrenoceptors

http://hdl.handle.net/10091/17335
http://hdl.handle.net/10091/17335
3e6a39b0-dfbc-4efa-8c52-d61908fb8025
名前 / ファイル ライセンス アクション
Male_lower_urinary_tract_symptoms.pdf Male_lower_urinary_tract_symptoms.pdf (224.2 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-01-21
タイトル
言語 en
タイトル Male lower urinary tract symptoms and a1D-adrenoceptors
言語
言語 eng
キーワード
主題Scheme Other
主題 a1-adrenoceptor subtypes
キーワード
主題Scheme Other
主題 bladder
キーワード
主題Scheme Other
主題 storage symptoms
キーワード
主題Scheme Other
主題 voiding dysfunction
キーワード
主題Scheme Other
主題 voiding symptoms
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Ishizuka, Osamu

× Ishizuka, Osamu

WEKO 6928

en Ishizuka, Osamu

Search repository
Imamura, Tetsuya

× Imamura, Tetsuya

WEKO 6929

en Imamura, Tetsuya

Search repository
Kurizaki, Yoshiki

× Kurizaki, Yoshiki

WEKO 6930

en Kurizaki, Yoshiki

Search repository
Nishizawa, Osamu

× Nishizawa, Osamu

WEKO 6931

en Nishizawa, Osamu

Search repository
Andersson, Karl-Erik

× Andersson, Karl-Erik

WEKO 6932

en Andersson, Karl-Erik

Search repository
信州大学研究者総覧へのリンク
氏名 Ishizuka, Osamu
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.gmfaHekh.html
信州大学研究者総覧へのリンク
氏名 Imamura, Tetsuya
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.ypACOmyC.html
信州大学研究者総覧へのリンク
氏名 Nishizawa, Osamu
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.WeyeWmyU.html
出版者
出版者 WILEY-BLACKWELL
引用
内容記述タイプ Other
内容記述 INTERNATIONAL JOURNAL OF UROLOGY. 20(1):73-78 (2013)
書誌情報 INTERNATIONAL JOURNAL OF UROLOGY

巻 20, 号 1, p. 73-78, 発行日 2013-01
抄録
内容記述タイプ Abstract
内容記述 Historically, a1-adrenoceptors have been classified into three subtypes (a1A, a1B and a1D) that are widely distributed in various organs. Research on the a1D-adrenoceptors in the bladder, urethra and prostate has focused on the relationship between expression levels and symptoms of bladder outlet obstruction, and the implications and functional roles of a1D-adrenoceptors subtypes in these organs. The a1D-adrenoceptor messenger ribonucleic acid and protein seem to be increased in obstructed bladders or small capacity bladders. In contrast, a1D-adrenoceptor subtype knock-out mice have been found to have a prolonged voiding interval. Interestingly, an a1D-adrenoceptor antagonist was found to inhibit the facilitation of afferent nerve activity for the micturition reflex induced by intravesical infusion of acetic acid. Clinically, patients who felt urgency at low filling volumes and had a small bladder capacity were found to have more a1D-adrenoceptor messenger ribonucleic acid in their bladder mucosa than patients who felt urgency at high filling volumes and had a large bladder capacity. An a1D-adrenoceptor antagonist was found to increase the first desired volume and the maximum desired volume while decreasing detrusor overactivity in pressure flow studies. Thus, a1D-adrenoceptors in the lower urinary tract might play an important role in the pathophysiology of lower urinary tract disorders.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ PISSN
収録物識別子 0919-8172
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA11042471
PubMed
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/23205498
関連名称 23205498
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1111/j.1442-2042.2012.03223.x
関連名称 10.1111/j.1442-2042.2012.03223.x
権利
権利情報 Copyright© 2012 The Japanese Urological Association
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
表示名 Web of Science
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000312989400010
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