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Male lower urinary tract symptoms and a1D-adrenoceptors
http://hdl.handle.net/10091/17335
http://hdl.handle.net/10091/173353e6a39b0-dfbc-4efa-8c52-d61908fb8025
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Male_lower_urinary_tract_symptoms.pdf (224.2 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||
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| 公開日 | 2014-01-21 | |||||||||||||||
| タイトル | ||||||||||||||||
| タイトル | Male lower urinary tract symptoms and a1D-adrenoceptors | |||||||||||||||
| 言語 | ||||||||||||||||
| 言語 | eng | |||||||||||||||
| DOI | ||||||||||||||||
| 関連識別子 | https://doi.org/10.1111/j.1442-2042.2012.03223.x | |||||||||||||||
| 関連名称 | 10.1111/j.1442-2042.2012.03223.x | |||||||||||||||
| キーワード | ||||||||||||||||
| 主題 | a1-adrenoceptor subtypes, bladder, storage symptoms, voiding dysfunction, voiding symptoms | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||
| タイプ | journal article | |||||||||||||||
| 著者 |
Ishizuka, Osamu
× Ishizuka, Osamu
× Imamura, Tetsuya
× Kurizaki, Yoshiki
× Nishizawa, Osamu
× Andersson, Karl-Erik
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| 信州大学研究者総覧へのリンク | ||||||||||||||||
| 氏名 | Ishizuka, Osamu | |||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.gmfaHekh.html | |||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||
| 氏名 | Imamura, Tetsuya | |||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.ypACOmyC.html | |||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||
| 氏名 | Nishizawa, Osamu | |||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.WeyeWmyU.html | |||||||||||||||
| 出版者 | ||||||||||||||||
| 出版者 | WILEY-BLACKWELL | |||||||||||||||
| 引用 | ||||||||||||||||
| 内容記述 | INTERNATIONAL JOURNAL OF UROLOGY. 20(1):73-78 (2013) | |||||||||||||||
| 書誌情報 |
INTERNATIONAL JOURNAL OF UROLOGY 巻 20, 号 1, p. 73-78, 発行日 2013-01 |
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| 抄録 | ||||||||||||||||
| 内容記述 | Historically, a1-adrenoceptors have been classified into three subtypes (a1A, a1B and a1D) that are widely distributed in various organs. Research on the a1D-adrenoceptors in the bladder, urethra and prostate has focused on the relationship between expression levels and symptoms of bladder outlet obstruction, and the implications and functional roles of a1D-adrenoceptors subtypes in these organs. The a1D-adrenoceptor messenger ribonucleic acid and protein seem to be increased in obstructed bladders or small capacity bladders. In contrast, a1D-adrenoceptor subtype knock-out mice have been found to have a prolonged voiding interval. Interestingly, an a1D-adrenoceptor antagonist was found to inhibit the facilitation of afferent nerve activity for the micturition reflex induced by intravesical infusion of acetic acid. Clinically, patients who felt urgency at low filling volumes and had a small bladder capacity were found to have more a1D-adrenoceptor messenger ribonucleic acid in their bladder mucosa than patients who felt urgency at high filling volumes and had a large bladder capacity. An a1D-adrenoceptor antagonist was found to increase the first desired volume and the maximum desired volume while decreasing detrusor overactivity in pressure flow studies. Thus, a1D-adrenoceptors in the lower urinary tract might play an important role in the pathophysiology of lower urinary tract disorders. | |||||||||||||||
| 資源タイプ（コンテンツの種類） | ||||||||||||||||
| ISSN | ||||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||||
| 収録物識別子 | 0919-8172 | |||||||||||||||
| 書誌レコードID | ||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||
| 収録物識別子 | AA11042471 | |||||||||||||||
| PubMed | ||||||||||||||||
| 識別子タイプ | PMID | |||||||||||||||
| 関連識別子 | https://pubmed.ncbi.nlm.nih.gov/23205498 | |||||||||||||||
| 関連名称 | 23205498 | |||||||||||||||
| 権利 | ||||||||||||||||
| 権利情報 | Copyright© 2012 The Japanese Urological Association | |||||||||||||||
| 出版タイプ | ||||||||||||||||
| 出版タイプ | AM | |||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||||
| WoS | ||||||||||||||||
| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000312989400010 | |||||||||||||||
